Prenatal Stress, Prematurity, and Asthma.
Pittsburgh, United States. In Obstet Gynecol Surv, Dec 2015
Prenatal stress may cause not only abnormalities in the HPA axis but also epigenetic changes in the fetal glucocorticoid receptor gene (NR3C1), leading to impaired glucocorticoid metabolism.
The Treatment of Cushing's Disease.
Napoli, Italy. In Endocr Rev, Aug 2015
The adrenal-directed drug ketoconazole is the most commonly used drug, mainly because of its rapid action, whereas the glucocorticoid receptor antagonist, mifepristone, is highly effective in controlling clinical comorbidities, mainly glucose intolerance, thus being a useful treatment for CD when it is associated with diabetes mellitus.