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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.


GES, Rem, REM1
The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008] (from NCBI)
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Top mentioned proteins: CAN, HAD, ACID, V1a, POLYMERASE
Papers on GES
A two-centre evaluation of RAPIDEC® CARBA NP for carbapenemase detection in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter spp.
Woodford et al., Stockholm, Sweden. In J Antimicrob Chemother, Feb 2016
The exceptions were one Klebsiella oxytoca, which was later found to produce GES-5 carbapenemase, one Pseudomonas aeruginosa with OprD loss and increased efflux, and one Enterobacter cloacae with impermeability.
miR-488 acts as a tumor suppressor gene in gastric cancer.
He et al., Xi'an, China. In Tumour Biol, Feb 2016
In addition, the expression of miR-488 was also lower in GC cell lines in contrast with the gastric epithelial cell line (GES).
miR-215 promotes malignant progression of gastric cancer by targeting RUNX1.
Shen et al., Beijing, China. In Oncotarget, Jan 2016
Ectopic expression of miR-215 in GES-1 and HGC-27 cells (low miR-215 expression) promoted cell growth, migration, invasion, and metastasis, and these were reversed in NCI-N87 cells (high miR-215 expression) after miR-215 downregulation.
Malignant transformation of human gastric epithelium cells via reactive oxygen species production and Wnt/β-catenin pathway activation following 40-week exposure to ochratoxin A.
Zhang et al., Shijiazhuang, China. In Cancer Lett, Jan 2016
We previously demonstrated that OTA treatment induced oxidative damage in human gastric epithelium cells (GES-1) in vitro.
RGK regulation of voltage-gated calcium channels.
Yang et al., New York City, United States. In Sci China Life Sci, 2015
They are a family of monomeric GTPases (Rad, Rem, Rem2, and Gem/Kir), in the superfamily of Ras GTPases, and they have two known functions: regulation of cytoskeletal dynamics including dendritic arborization and inhibition of VGCCs.
Epigenetic regulation of CDH1 exon 8 alternative splicing in gastric cancer.
Wang et al., Nanjing, China. In Bmc Cancer, 2014
RESULTS: Greater CDH1 1054del83 transcripts were observed in gastric cancer (GC) cell lines than human gastric mucosal epithelial cell line GES-1.
Inhibition of Voltage-Gated Calcium Channels by RGK Proteins.
Yang et al., New York City, United States. In Curr Mol Pharmacol, 2014
RGKs (Rad, Rem, Rem2 and Gem/Kir) are a family of monomeric small GTPases belonging to the superfamily of Ras GTPases.
Silencing of ZNF139-siRNA induces apoptosis in human gastric cancer cell line BGC823.
Zhang et al., Shijiazhuang, China. In Int J Clin Exp Pathol, 2014
METHODS: Expression of ZNF139 in GC tissues, adjacent normal tissues, GC cell lines MKN28, SGC7901, BGC823 and that in gastric epithelial cell line GES-1 were tested.
Microarray analysis of Long non-coding RNA expression profiles in human gastric cells and tissues with Helicobacter pylori Infection.
Shao et al., Zhenjiang, China. In Bmc Med Genomics, 2014
This study aimed to identify the dysregulated lncRNAs in human gastric epithelial cells and tissues infected with H.pylori. METHODS: The aberrant expression profiles of lncRNAs and mRNAs in GES-1 cells with or without H.pylori infection were explored by microarray analysis.
Molecular mechanisms of activity-dependent changes in dendritic morphology: role of RGK proteins.
Paradis et al., Waltham, United States. In Trends Neurosci, 2014
In recent years, there has been an emerging appreciation of the importance of the Rad/Rem/Rem2/Gem/Kir (RGK) GTPases as mediators of activity-dependent structural plasticity.
Regulation of voltage-dependent calcium channels by RGK proteins.
Colecraft et al., New York City, United States. In Biochim Biophys Acta, 2013
RGK proteins belong to the Ras superfamily of monomeric G-proteins, and currently include four members - Rad, Rem, Rem2, and Gem/Kir.
Nanotechnology-based gene-eluting stents.
Seifalian et al., London, United Kingdom. In Mol Pharm, 2013
Gene-eluting stents (GES) have recently been proposed as a novel method of circumventing problems seen in BMS and DES.
Polycistronic transcription of fused cassettes and identification of translation initiation signals in an unusual gene cassette array from Pseudomonas aeruginosa.
Vicente et al., Rio de Janeiro, Brazil. In F1000res, 2012
The aim of this study was to evaluate the dynamic of mobilization and transcription of the gcu14-bla GES-1 /aacA4 gene cassette array, which harbours a fused gene cassette represented by bla GES-1 /aacA4.
Promoter-driven splicing regulation in fission yeast.
Ayté et al., Barcelona, Spain. In Nature, 2008
Rem1 is a cyclin that is only expressed during meiosis in the fission yeast Schizosaccharomyces pombe.
Plasma membrane targeting is essential for Rem-mediated Ca2+ channel inhibition.
Andres et al., Lexington, United States. In J Biol Chem, 2007
a role for the Rem C terminus in plasma membrane localization through association with phosphatidylinositol lipids.
Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport.
Béguin et al., Singapore, Singapore. In Traffic, 2007
Nuclear localization of RGK proteins (Rad, Rem, and Rem2) contributes to the suppression of RGK-mediated cell shape remodeling.
L-type calcium channel alpha-subunit and protein kinase inhibitors modulate Rem-mediated regulation of current.
Satin et al., Lexington, United States. In Am J Physiol Heart Circ Physiol, 2006
We conclude that Rem is capable of regulating L-type current, that release of Rem block is modulated by cellular kinase pathways, and that the Ca(V)1.2 COOH terminus contributes to Rem-dependent channel inhibition.
Analysis of the complex between Ca2+ channel beta-subunit and the Rem GTPase.
Andres et al., Lexington, United States. In J Biol Chem, 2006
Rem-dependent Ca2+ channel modulation involves formation of a Rem x CaVbeta x alpha-interaction domain regulatory complex without the need to disrupt CaValpha1 x CaVbeta association or alter CaValpha1 expression at the plasma membrane.
Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases.
Andres et al., Lexington, United States. In Proc Natl Acad Sci U S A, 2003
both Rem and Rad bind directly to Ca2+ channel beta-subunits (CaV beta) in vivo
Autologous marrow transplantation for patients with acute myeloid leukemia in untreated first relapse or in second complete remission.
Martin et al., Seattle, United States. In J Clin Oncol, 1993
All REL1 patients and four REM2 patients had marrow stored during first remission (REM1).
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