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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Protein phosphatase 2, regulatory subunit B'', gamma

G41, G5PR, Protein phosphatase subunit G5PR
Top mentioned proteins: JNK, BCR, Bim, HAD, Wnt5a
Papers on G41
JNK regulatory molecule G5PR induces IgG autoantibody-producing plasmablasts from peritoneal B1a cells.
Sakaguchi et al., Kumamoto, Japan. In J Immunol, Mar 2015
Previous studies show reduced JNK signaling in peritoneal B1a cells of female New Zealand Black mice and an abnormal increase of protein phosphatase 2A subunit G5PR that regulates BCR-mediated JNK signaling as a cause of autoimmunity.
Transgenic overexpression of G5PR that is normally augmented in centrocytes impairs the enrichment of high-affinity antigen-specific B cells, increases peritoneal B-1a cells, and induces autoimmunity in aged female mice.
Sakaguchi et al., Kumamoto, Japan. In J Immunol, 2012
G5PR expression is markedly augmented in the centrocytes of germinal centers after immunization of transgenic mice with T cell-dependent antigen.
Phosphorylation-dependent association of the G4-1/G5PR regulatory subunit with IKKβ negatively modulates NF-κB activation through recruitment of protein phosphatase 5.
Chou et al., Taipei, Taiwan. In Biochem J, 2011
In the present study, we report a regulatory subunit of PP5 (protein phosphatase 5), G4-1, that physically interacts with IKKβ [IκB (inhibitor of NF-κB) kinase β] and negatively regulates NF-κB activation.
Protein phosphatase subunit G5PR that regulates the JNK-mediated apoptosis signal is essential for the survival of CD4 and CD8 double-positive thymocytes.
Sakaguchi et al., Kumamoto, Japan. In Mol Immunol, 2008
G5PR regulates the thymocyte unique apoptotic signal involved in JNK-mediated Caspase-3 activation but not in Bim activation.
Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection.
Haynes et al., Durham, United States. In J Virol, 2008
Two human monoclonal antibodies (MAbs) (2F5 and 4E10) against the human immunodeficiency virus type 1 (HIV-1) envelope g41 cluster II membrane proximal external region (MPER) broadly neutralize HIV-1 primary isolates.
BCR-crosslinking induces a transcription of protein phosphatase component G5PR that is required for mature B-cell survival.
Sakaguchi et al., Kumamoto, Japan. In Biochem Biophys Res Commun, 2006
We examined the transcription of a protein phosphatase subunit G5PR in immature and mature B-cells, because absence of this factor augmented cell sensitivity to AICD, associated with increased activation of JNK and Bim.
Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis.
Sakaguchi et al., Kumamoto, Japan. In J Exp Med, 2005
G5PR is required for the B cell receptor-mediated proliferation associated with the prevention of activation-induced cell death in mature B cells.
MCM3-binding GANP DNA-primase is associated with a novel phosphatase component G5PR.
Sakaguchi et al., Kumamoto, Japan. In Genes Cells, 2002
RESULTS: Using the 1 kb fragment (G5) of the ganp cDNA, we identified a clone named G5PR that is structurally homologous to known regulatory subunits of protein phosphatases (PPases) and determined the association of G5PR with GANP in vivo in the DNA transfectant.
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