GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
fucosyltransferase, HSC, FUT1
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group. [provided by RefSeq, Jul 2008] (from
Wilcox, Milwaukee, United States. In Blood, Feb 2016
UNASSIGNED: Hematopoietic stem cells (HSC) can be safely collected from the body, genetically modified and re infused into a patient with the goal to express the transgene product for an individual's lifetime.
Raizada et al., Gainesville, United States. In Hypertension, Feb 2016
This, coupled with the intimate involvement of the hyperactive renin-angiotensin system in hypertension, led us to investigate the hypothesis that chronic angiotensin II (Ang II) infusion affects hematopoietic stem cell (HSC) regulation at the level of the bone marrow.
Li et al., Kansas City, United States. In Cell Stem Cell, Dec 2015
Through transcriptome profiling in 17 hematopoietic cell types, we found that ncRNAs expressed from the Dlk1-Gtl2 locus are predominantly enriched in fetal liver HSCs and the adult LT-HSC population and sustain long-term HSC functionality.
Morrison et al., Dallas, United States. In Nature, Nov 2015
We find that approximately 30% of α-catulin-GFP(+)c-kit(+) cells give long-term multilineage reconstitution of irradiated mice, indicating that α-catulin-GFP(+)c-kit(+) cells are comparable in HSC purity to cells obtained using the best markers currently available.
Zeiser et al., Freiburg, Germany. In Mediators Inflamm, 2014
The characterization of the cellular and molecular networks operating in the HSC niche has opened new perspectives for the understanding of the bidirectional cross-talk between HSCs and stromal cell populations in normal and malignant conditions.
Robertson et al., Adelaide, Australia. In Mol Hum Reprod, 2012
Macrophage-derived factors including LIF might facilitate development of an implantation-receptive endometrium by regulating surface glycan structures in epithelial cells by up-regulating FUT1 and FUT2.
Yan et al., Hangzhou, China. In Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2011
mutations of FUT1 gene did not affect the RNA and protein expression levels, but the enzyme activity of cells with FUT1 mutations was significantly decreased which resulted in the reduced expressin of H antigen.
Kiyono et al., Tokyo, Japan. In Biochem Biophys Res Commun, 2011
These results indicate that Fut2-mediated fucosylated epithelial cells (F-ECs) share M cell-related fucosylated molecules but maintain distinctive EC characteristics, Fut1 is, therefore, a reliable marker for M cells.