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Feminization 1 homolog b

Fem1b, F1Aalpha
Top mentioned proteins: ACID, PrP, SET, CAN, HAD
Papers on Fem1b
Analysis of the expression of PHTF1 and related genes in acute lymphoblastic leukemia.
Du et al., Guangzhou, China. In Cancer Cell Int, 2014
The PHTF1, BCL11B, FEM1B and Apaf-1 gene expression levels and correlations were analyzed in patients with primary ALL (including T-ALL and B-ALL) and healthy individuals (HIs).
Gene expression profiles for the prediction of progression-free survival in diffuse large B cell lymphoma: results of a DASL assay.
Kim et al., Seoul, South Korea. In Ann Hematol, 2014
We identified a set of genes whose expression provided prognostic indicators from whole data set (PRKCDBP, CASP10, FAM3C, KCNK12, MAN1A2, PRND, RAB1A, TMEM39B, SLC6A6, MMP12, FEM1B, C3orh37, RBP1, HK1, LOC400464, KIAA0746, and SLC25A23).
Mouse Fem1b interacts with and induces ubiquitin-mediated degradation of Ankrd37.
Han et al., Beijing, China. In Gene, 2011
Fem1b is a binding partner of Ankrd37, and their interaction resulted in Ankrd37 degradation through the ubiquitin-mediated proteolysis pathway.
Fem1b antigen in the stool of ApcMin mice as a biomarker of early Wnt signaling activation in intestinal neoplasia.
Maher et al., Dallas, United States. In Cancer Epidemiol, 2011
Increased Fem1b is associated with intestinal neoplasia.
Family-based analysis of candidate genes for polycystic ovary syndrome.
Spielman et al., Philadelphia, United States. In J Clin Endocrinol Metab, 2010
SNPs in four of the other 26 putative candidate genes that were tested using the TDT were nominally significant (ACVR2A, POMC, FEM1B, and SGTA).
Fem1b, a proapoptotic protein, mediates proteasome inhibitor-induced apoptosis of human colon cancer cells.
Maher et al., Dallas, United States. In Mol Carcinog, 2010
the proapoptotic protein Fem1b is downregulated by the proteasome in malignant colon cancer cells and mediates proteasome inhibitor-induced apoptosis of these cells
Proteomic profiles of mesenchymal stem cells induced by a liver differentiation protocol.
Hongeng et al., Bangkok, Thailand. In Int J Mol Sci, 2009
In addition the results of proteomic study demonstrated increases expression of FEM1B, PSMC2 and disulfide-isomerase A3 in MSCs treated with the liver differentiation protocol.
Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress.
Shieh et al., Taipei, Taiwan. In Oncogene, 2009
FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress.
FEM1A and FEM1B: novel candidate genes for polycystic ovary syndrome.
Azziz et al., Los Angeles, United States. In Hum Reprod, 2008
This study presents evidence suggesting a role for FEM1A and FEM1B in the pathogenesis of polycystic ovary syndrome. Only FEM1B variants were associated with insulin-related traits in PCOS women.
Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development.
Shen et al., United States. In Dev Dyn, 2008
Fem1b may have a conserved role in the generation of sexual dimorphism through its interaction with Nkx3.1 in the developing prostate gland
Putative homeodomain transcription factor 1 interacts with the feminization factor homolog fem1b in male germ cells.
Raich et al., Saint George's, Grenada. In Biol Reprod, 2005
neither FEM1B nor PHTF1 are directly implicated in apoptosis in testis tissue
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
Nakayama et al., Fukuoka, Japan. In Genes Dev, 2005
We also identify LRR-1 and FEM1B as proteins that share a region of homology with VHL (the VHL box, including the BC box and downstream residues) and associate with Cul2-Rbx1.
The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis.
Yu et al., Singapore, Singapore. In J Biol Chem, 2001
Recently, a mammalian homologue of the C. elegans sex-determining protein FEM-1, F1Aalpha, has been described.
The Caenorhabditis elegans sex determination protein FEM-1 is a CED-3 substrate that associates with CED-4 and mediates apoptosis in mammalian cells.
Yu et al., Singapore, Singapore. In J Biol Chem, 2000
Recently, a mammalian pro-apoptotic protein named F1Aalpha has been identified.
Rapid communication: the human FEM1B gene maps to chromosome 15q22 and is excluded as the gene for Bardet-Biedl syndrome, type 4.
Maher et al., Jackson, United States. In Am J Med Sci, 2000
We have identified a novel human gene, FEM1B, that encodes a protein virtually identical to that encoded by the mouse gene Fem1b.
Sequence, organization, and expression of the human FEM1B gene.
Maher et al., Jackson, United States. In Biochem Biophys Res Commun, 2000
FEM1B encodes a protein, designated FEM1beta, that shows >99% amino acid identity to the corresponding mouse Fem1b protein, including 100% amino acid identity in the N-terminal ANK repeat domain.
F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis.
Yu et al., Singapore, Singapore. In J Biol Chem, 1999
Here, we report the cloning of an ankyrin repeat-containing protein, termed F1Aalpha, in a yeast two-hybrid screen using the cytoplasmic domain of Fas (CD95/APO-1) as bait.
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