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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

F-box protein 40

Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: Ubiquitin, MyoD, M2-PK, AGE, eIF3f
Papers on FBXO40
Regulation of ubiquitin proteasome pathway molecular markers in response to endurance and resistance exercise and training.
Vissing et al., Australia. In Pflugers Arch, Jul 2015
This study examined mRNA and/or protein levels of molecular markers of the ubiquitin proteasome pathway (UPP), including FBXO32 (atrogin-1), MURF-1, FBXO40, FOXO1 and FOXO3.
Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise.
Lamon et al., Australia. In Front Physiol, 2013
MURF1, atrogin-1 and FBXO40, their substrate targets PKM2, myogenin, MYOD, MHC and EIF3F as well as MURF1 and atrogin-1 transcriptional regulators FOXO1 and FOXO3 gene and/or protein expression levels were measured via real time PCR and western blotting, respectively.
A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.
Zagury et al., Paris, France. In J Invest Dermatol, 2013
In addition, it was also in LD with another SNP that increases the expression of the FBXO40 gene in the skin.
Molecular characterization and association analysis of FBXO40 with partial hematological indexes in pig.
Li et al., Beijing, China. In Mol Biol Rep, 2010
FBXO40, a member of this large family, alters its expression pattern in muscle atrophy.
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes.
Hakonarson et al., Philadelphia, United States. In Nature, 2009
Furthermore, CNVs within or surrounding genes involved in the ubiquitin pathways, including UBE3A, PARK2, RFWD2 and FBXO40, were affected by CNVs not observed in controls (P = 3.3 x 10(-3)).
FBXO40, a gene encoding a novel muscle-specific F-box protein, is upregulated in denervation-related muscle atrophy.
Zhu et al., Beijing, China. In Gene, 2008
FBXO40 may function as a regulator involved in the postnatal myogenesis.
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