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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.


This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain. It is believed to be a member of the band 4.1 superfamily whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, V1a, Rhodopsin, CAN, GEF
Papers on FARP1
MAP4K4 Is a Threonine Kinase That Phosphorylates FARP1.
Carpino et al., United States. In Acs Chem Biol, Jan 2016
We showed that MAP4K4 directly phosphorylates and coimmunoprecipitates with FERM, RhoGEF, and pleckstrin domain-containing protein 1 (FARP1).
DNA adducts induced by in vitro activation of extracts of diesel and biodiesel exhaust particles.
DeMarini et al., United States. In Inhal Toxicol, Sep 2015
METHODS: We examined two different DEP from petroleum diesel (C-DEP and B0), one from soy bean oil biodiesel (B100) and one from combustion of a blend of 20% B100 and 80% B0 (B20) for in vitro DNA adduct-forming potential under oxidative or nitroreductive conditions in the presence of calf thymus DNA as well as in vivo in Salmonella TA100.
The Rif GTPase regulates cytoskeletal signaling from plexinA4 to promote neurite retraction.
Mellor et al., Hohhot, China. In Neurosci Lett, Apr 2015
We found that Rif interacts with FARP1, a neuronal activator of the RhoA GTPase.
Genes from a translational analysis support a multifactorial nature of white matter hyperintensities.
Wardlaw et al., Edinburgh, United Kingdom. In Stroke, Feb 2015
RESULTS: Of 126 spontaneously hypertensive stroke-prone rat genes, 10 were nominally associated with WMH volume or score in subjects from LBC1936, of which 5 (AFP, ALB, GNAI1, RBM8a, and MRPL18) were associated with both WMH volume and score (P<0.05); 2 of the 10 (XPNPEP1, P=6.7×10(-5); FARP1, P=0.024) plus another spontaneously hypertensive stroke-prone rat gene (USMG5, P=0.00014), on chromosomes 10, 13, and 10 respectively, were associated with WMH in subjects from CHARGE.
TIL-type protease inhibitors may be used as targeted resistance factors to enhance silkworm defenses against invasive fungi.
Xia et al., Chongqing, China. In Insect Biochem Mol Biol, Feb 2015
In activity assays, BmSPI39 potently inhibited the virulence protease CDEP-1 of Beauveria bassiana, suggesting that it might suppress the fungal penetration of the silkworm integument by inhibiting the cuticle-degrading proteases secreted by the fungus.
Expression of a toll signaling regulator serpin in a mycoinsecticide for increased virulence.
Fan et al., In Appl Environ Microbiol, 2014
Expression of Spn43Ac had no effect on the activity of the endogenous B. bassianaderived cuticle-degrading protease (CDEP-1).
Bioassay-directed fractionation and sub-fractionation for mutagenicity and chemical analysis of diesel exhaust particles.
Demarini et al., Chapel Hill, United States. In Environ Mol Mutagen, 2013
We collected a compressor-generated DEP (C-DEP) and characterized it by conducting bioassay-directed fractionation of the extractable organics in Salmonella and correlating the results by hierarchical clustering with the concentrations of 32 polycyclic aromatic hydrocarbons (PAHs).
A novel protease inhibitor in Bombyx mori is involved in defense against Beauveria bassiana.
Xia et al., Chongqing, China. In Insect Biochem Mol Biol, 2012
An activity assay suggested that BmSPI38 potently inactivated the insecticidal cuticle-degrading enzyme (CDEP-1) produced by B. bassiana and subtilisin A produced by Bacillus licheniformis.
Novel mutation and three other sequence variants segregating with phenotype at keratoconus 13q32 susceptibility locus.
Gajecka et al., Poznań, Poland. In Eur J Hum Genet, 2012
Consequently, we have chosen eight positional candidate genes in this region: MBNL1, IPO5, FARP1, RNF113B, STK24, DOCK9, ZIC5 and ZIC2, and sequenced all of them in 51 individuals from Ecuadorian KTCN families and 105 matching controls.
Increased virulence using engineered protease-chitin binding domain hybrid expressed in the entomopathogenic fungus Beauveria bassiana.
Pei et al., Beibei, China. In Microb Pathog, 2010
In order to better target cuticle protein-chitin structures and accelerate penetration speed, a hybrid protease (CDEP-BmChBD) was constructed by fusion of a chitin binding domain BmChBD from Bombyx mori chitinase to the C-terminal of CDEP-1, a subtilisin-like protease from B. bassiana.
Consistent Differential Expression Pattern (CDEP) on microarray to identify genes related to metastatic behavior.
Zheng et al., Charleston, United States. In Bmc Bioinformatics, 2010
The objective of this study is to develop a novel meta-analysis approach, Consistent Differential Expression Pattern (CDEP), to identify genes with common differential expression patterns across different datasets.
FARP1 promotes the dendritic growth of spinal motor neuron subtypes through transmembrane Semaphorin6A and PlexinA4 signaling.
Sockanathan et al., Baltimore, United States. In Neuron, 2009
Here, we show that retinoids induce the expression of the FERM Rho-GEF protein FARP1 in the developing spinal cord.
Differential potentiation of allergic lung disease in mice exposed to chemically distinct diesel samples.
Gilmour et al., Chapel Hill, United States. In Toxicol Sci, 2009
Mice were instilled intranasally with saline or 150 microg of N-DEP, A-DEP, or C-DEP with or without 20 microg of ovalbumin (OVA) on days 0 and 13, and were subsequently challenged with 20 microg of OVA on days 23, 26, and 29.
Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood.
Sharp et al., Sacramento, United States. In Bmc Med Genomics, 2008
To validate the best candidate genes, we performed quantitative RT-PCR on a subset of 10 genes (TRAP1, DECR1, FPGS, FARP1, MAPRE2, PEX16, GINS2, CRY2, CSNK1G2 and A4GALT), 4 commonly employed reference genes (GAPDH, ACTB, B2M and HMBS) and PPIB, previously reported to be stably expressed in blood.
Validation of the emotional eating scale adapted for use in children and adolescents (EES-C).
Yanovski et al., Bethesda, United States. In Int J Eat Disord, 2007
RESULTS: A factor analysis generated three subscales: eating in response to anxiety, anger, and frustration (EES-C-AAF), depressive symptoms (EES-C-DEP), and feeling unsettled (EES-C-UNS).
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