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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Family with sequence similarity 3, member A

Top mentioned proteins: Akt, Insulin, PI3K, FAM3C, ORF9
Papers on FAM3A
FAM3A Protects HT22 Cells Against Hydrogen Peroxide-Induced Oxidative Stress Through Activation of PI3K/Akt but not MEK/ERK Pathway.
Zhang et al., In Cell Physiol Biochem, 2014
FAM3A is the first member of family with sequence similarity 3 (FAM3) gene family and its biological function remains largely unknown.
FAM3A promotes vascular smooth muscle cell proliferation and migration and exacerbates neointima formation in rat artery after balloon injury.
Yang et al., Beijing, China. In J Mol Cell Cardiol, 2014
The biological function of FAM3A, the first member of family with sequence similarity 3 (FAM3) gene family, remains largely unknown.
FAM3A activates PI3K p110α/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis.
Guan et al., Beijing, China. In Hepatology, 2014
UNLABELLED: FAM3A belongs to a novel cytokine-like gene family, and its physiological role remains largely unknown.
Identification of novel molecular markers for prognosis estimation of acute myeloid leukemia: over-expression of PDCD7, FIS1 and Ang2 may indicate poor prognosis in pretreatment patients with acute myeloid leukemia.
Meng et al., Guangzhou, China. In Plos One, 2013
For further improving the prognosis evaluation system, we investigated the transcripts levels of PDCD7, FIS1, FAM3A, CA6, APP, KLRF1, ATCAY, GGT5 and Ang2 in 97 AML patients and 30 non-malignant controls, and validated using the published microarray data from 225 cytogenetically normal AML (CN-AML) patients treated according to the German AMLCG-1999 protocol.
Family with sequence similarity 3 gene family and nonalcoholic fatty liver disease.
Guan et al., Beijing, China. In J Gastroenterol Hepatol, 2013
The family with sequence similarity 3 (FAM3) gene family is a cytokine-like gene family with four members designated FAM3A, FAM3B, FAM3C, and FAM3D, respectively.
FAM3A is a target gene of peroxisome proliferator-activated receptor gamma.
Yang et al., Beijing, China. In Biochim Biophys Acta, 2013
BACKGROUND: To date, the biological function of FAM3A, the first member of FAM3 gene family, remains unknown.
Drosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity.
Netea et al., Nijmegen, Netherlands. In Antimicrob Agents Chemother, 2008
In the present study, we report a putative human homologue of the Drosophila-derived drosomycin, designated drosomycin-like defensin (DLD), with specific antifungal activity. [DLD]
GG: a domain involved in phage LTF apparatus and implicated in human MEB and non-syndromic hearing loss diseases.
Yu et al., Chicago, United States. In Febs Lett, 2006
Here, we report the identification of a novel domain--GG (domain in KIAA1199, FAM3, POMGnT1 and Tmem2 proteins, with two well-conserved glycine residues), present in eukaryotic FAM3 superfamily (FAM3A, FAM3B, FAM3C and FAM3D), POMGnT1 (protein O-linked mannose beta-1,2-N-acetylglucosaminyltransferase), TEM2 proteins as well as phage gp35 proteins.
Cloning, expression, and initial characterization of a novel cytokine-like gene family.
Young et al., King of Prussia, United States. In Genomics, 2002
Expressed prominently in the vascular endothelium, particularly capillaries, also in islets of Langerhans.
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