[Transglutaminase and neurodegenerative diseases].
Changsha, China. In Zhonghua Yi Xue Yi Chuan Xue Za Zhi, Aug 2015
The TGase family found in rodents and human contains 9 types, including TG1-7, blood coagulation factor XIIIa and erythrocyte membrane protein 4.2, with the former 8 types possessing catalytic activity.
Factor XIIIA (cross)links AT1 receptors to atherosclerosis.
San Diego, United States. In Cell, 2004
In this issue of Cell, AbdAlla et al. (2004) provide evidence that pathogenic actions of angiotensin II involve covalent crosslinking of angiotensin AT1 receptors by factor XIIIA transglutaminase, resulting in stable receptor dimers with enhanced signaling properties.