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ETR1 ethylene receptor 1

Similar to prokaryote sensory transduction proteins. Contains a histidine kinase and a response regulator domain. Homodimer. Membrane component. Binds ethylene. Mutations affect ethylene binding and metabolism of other plant hormones such as auxin, cytokinins, ABA and gibberellic acid. Ethylene receptor. Has histidine kinase activity. Is regulated by RTE1. (from NCBI)
Top mentioned proteins: ACID, HAD, CAN, V1a, NPR1
Papers on etr1
ZAP1-mediated modulation of triacylglycerol levels in yeast by transcriptional control of mitochondrial fatty acid biosynthesis.
Rajasekharan et al., Mysore, India. In Mol Microbiol, Jan 2016
The expression of ETR1 is reduced in zap1Δ.
Ethylene signalling is mediating the early cadmium-induced oxidative challenge in Arabidopsis thaliana.
Cuypers et al., Diepenbeek, Belgium. In Plant Sci, Oct 2015
The effects of 24 or 72 h exposure to 5 μM Cd on plant growth and several oxidative stress-related parameters were compared between wild-type (WT) and ethylene insensitive mutants (etr1-1, ein2-1, ein3-1).
Identification of Regions in the Receiver Domain of the ETHYLENE RESPONSE1 Ethylene Receptor of Arabidopsis Important for Functional Divergence.
Binder et al., Knoxville, United States. In Plant Physiol, Sep 2015
However, the ETHYLENE RESPONSE1 (ETR1) ethylene receptor has unique, and sometimes contrasting, roles from the other receptor isoforms.
Ethylene resistance in flowering ornamental plants - improvements and future perspectives.
Müller et al., Taastrup, Denmark. In Hortic Res, 2014
Elements of the ethylene pathway that appear particularly promising in this respect include ethylene receptors as ETR1, and transcription factors such as EIN3.
Ethylene Modulates Sphingolipid Synthesis in Arabidopsis.
Yao et al., Guangzhou, China. In Front Plant Sci, 2014
The etr1-1 and ein2 mutants, which have disrupted ethylene signaling, exhibited hypersensitivity to FB1; by contrast, the eto1-1 and ctr1-1 mutants, which have enhanced ethylene signaling, exhibited increased tolerance to FB1.
Partially dissecting the steady-state electron fluxes in Photosystem I in wild-type and pgr5 and ndh mutants of Arabidopsis.
Chow et al., Taiwan. In Front Plant Sci, 2014
We obtained the linear electron flux (LEFO2) through both photosystems and the total electron flux through PS I (ETR1) in Arabidopsis in CO2-enriched air.
Ethylene, a key factor in the regulation of seed dormancy.
El-Maarouf-Bouteau et al., Paris, France. In Front Plant Sci, 2013
Studies using inhibitors of ethylene biosynthesis or of ethylene action and analysis of mutant lines altered in genes involved in the ethylene signaling pathway (etr1, ein2, ain1, etr1, and erf1) demonstrate the involvement of ethylene in the regulation of germination and dormancy.
Ethylene signaling and regulation in plant growth and stress responses.
Dong et al., Qingdao, China. In Plant Cell Rep, 2013
Since the cloning of the first ethylene receptor ETR1 from Arabidopsis, a large number of studies have steadily improved our understanding of the receptors and downstream components in ethylene signal transduction pathway.
Arabidopsis RTE1 is essential to ethylene receptor ETR1 amino-terminal signaling independent of CTR1.
Wen et al., Shanghai, China. In Plant Physiol, 2012
The roles of CTR1 and RTE1 in ETR1 N-terminal signaling, were evaluated.
Histidine kinase activity of the ethylene receptor ETR1 facilitates the ethylene response in Arabidopsis.
Schaller et al., United States. In Plant Physiol, 2012
Histidine kinase activity of ETR1 is not required for but plays a modulating role in the regulation of ethylene responses.
Arabidopsis ETR1 and ERS1 differentially repress the ethylene response in combination with other ethylene receptor genes.
Wen et al., Shanghai, China. In Plant Physiol, 2012
Both ETR1 and EIN4 are predominantly required for the repression of ethylene responses by ERS1.
Protein kinase domain of CTR1 from Arabidopsis thaliana promotes ethylene receptor cross talk.
Mueller-Dieckmann et al., Hamburg, Germany. In J Mol Biol, 2012
Together with a front-to-front activation interface, the active protein kinase dimers thereby engage in interactions that promote CTR1-mediated cross talk between ethylene receptor clusters.
Giant chloroplast development in ethylene response1-1 is caused by a second mutation in ACCUMULATION AND REPLICATION OF CHLOROPLAST3 in Arabidopsis.
Yoo et al., Suwŏn, South Korea. In Mol Cells, 2012
Transgenic and genetic analyses revealed that this organelle abnormality was not linked to etr1-1 or ethylene signaling, but linked to a second mutation in ARC3, which was further verified by genetic complementation analysis.
(111)In-Labeled lexatumumab
Chopra, Bethesda, United States. In Unknown Journal, 2009
A similar mAb, mapatumumab (TRM-1 or HGS-ETR1), is a TRAIL-R2 mAb that acts as an agonist specifically for the TRAIL-R2 and has been approved by the USFDA for clinical trials.
(111)In-Labeled mapatumumab
Chopra, Bethesda, United States. In Unknown Journal, 2009
Mapatumumab (TRM-1 or HGS-ETR1) is a TRAIL-R1 monoclonal Ab (mAb) that targets TRAIL-R1; it is under commercial development and has been approved for clinical trials by the United States Food and Drug Administration (USFDA) to treat various cancers.
Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand receptor-1.
Cohen et al., San Antonio, United States. In J Clin Oncol, 2007
PURPOSE: To assess the safety, pharmacokinetics, and preliminary evidence of antitumor activity of mapatumumab (HGS-ETR1, TRM-1), a fully human agonist monoclonal antibody directed to the tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1).
Plant responses to ethylene gas are mediated by SCF(EBF1/EBF2)-dependent proteolysis of EIN3 transcription factor.
Ecker et al., Los Angeles, United States. In Cell, 2004
Here, we report that EIN3 protein levels rapidly increase in response to ethylene and this response requires several ethylene-signaling pathway components including the ethylene receptors (ETR1 and EIN4), CTR1, EIN2, EIN5, and EIN6.
Differential regulation of EIN3 stability by glucose and ethylene signalling in plants.
Sheen et al., Kurashiki, Japan. In Nature, 2003
The ethylene-insensitive etr1 and ein2 mutants have glo phenotypes, whereas the constitutive ethylene signalling mutant ctr1 is allelic to gin4 (refs 4, 5).
A copper cofactor for the ethylene receptor ETR1 from Arabidopsis.
Bleecker et al., Madison, United States. In Science, 1999
The ETR1 receptor from Arabidopsis binds the gaseous hormone ethylene.
Ethylene responses are negatively regulated by a receptor gene family in Arabidopsis thaliana.
Meyerowitz et al., Pasadena, United States. In Cell, 1998
A family of genes including ETR1, ETR2, EIN4, ERS1, and ERS2 is implicated in ethylene perception in Arabidopsis thaliana.
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