Antiviral role of grouper STING against iridovirus infection.
Guangzhou, China. In Fish Shellfish Immunol, Nov 2015
Stimulator of interferon genes (STING, also known as MITA, ERIS, MPYS or TMEM173) has been identified as a central component in the innate immune response to cytosolic DNA and RNA derived from different pathogens.
Wolfram syndrome 1 and Wolfram syndrome 2.
Messina, Italy. In Curr Opin Pediatr, 2012
The CISD2-encoded protein ERIS (endoplasmic reticulum intermembrane small protein) also localizes to ER, but does not interact directly with wolframin.
STING is a direct innate immune sensor of cyclic di-GMP.
Berkeley, United States. In Nature, 2011
In addition, a transmembrane protein called STING (stimulator of IFN genes; also known as MITA, ERIS, MPYS and TMEM173) functions as an essential signalling adaptor, linking the cytosolic detection of DNA to the TBK1-IRF3 signalling axis.