Reductions in eosinophil biomarkers by benralizumab in patients with asthma.
Gaithersburg, United States. In Respir Med, Feb 2016
Blood eosinophils, IL-5, eosinophil-derived neurotoxin (EDN), eosinophil cationic protein (ECP), eotaxin/chemokine (C-C motif) 11 (CCL11), eotaxin-2/CCL24, tumor necrosis factor (TNF), and interferon-γ (IFN-γ) were measured at baseline and post-treatment.
The role of hypoxia-induced genes in ovarian angiogenesis.
Jerusalem, Israel. In Reprod Fertil Dev, 2012
Special emphasis is given to hypoxia-induced, luteal cell-specific expression of multiple genes (vascular endothelial growth factor A (VEGFA), fibroblast growth factor 2 (FGF-2), prokineticin receptor 2 (PK-R2), stanniocalcin 1 (STC-1) and endothelin 2 (EDN-2) that participate in the angiogenic process during CL formation.
The antipathogen activities of eosinophil cationic protein.
Barcelona, Spain. In Curr Pharm Biotechnol, 2008
Although eosinophils and ECP are primarily associated with the host defense against nonphagocytosable pathogens, such as helminthic parasites, ECP has also an antibacterial activity, which is not shared by the other, closely-related eosinophil ribonuclease, the eosinophil derived neurotoxin (EDN).