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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Eosinophil peroxidase

eosinophil peroxidase
Top mentioned proteins: erythropoietin, myeloperoxidase, CAN, HAD, IL-5
Papers using eosinophil peroxidase antibodies
Eosinophil transendothelial migration induced by cytokines. I. Role of endothelial and eosinophil adhesion molecules in IL-1 beta-induced transendothelial migration
Heinemann Akos et al., In Cellular and Molecular Life Sciences, 1991
... Goat antibody against eosinophil peroxidase was from Santa Cruz Biotechnology (Heidelberg, Germany) ...
Papers on eosinophil peroxidase
Enzymatic oxidative biodegradation of nanoparticles: Mechanisms, significance and applications.
Kagan et al., Pittsburgh, United States. In Toxicol Appl Pharmacol, Feb 2016
Here, we review the role and contribution of different oxidative enzymes of inflammatory cells - myeloperoxidase, eosinophil peroxidase, lactoperoxidase, hemoglobin, and xanthine oxidase - to the reactions of nanoparticle biodegradation.
The metabolism and de-bromination of bromotyrosine in vivo.
Moore et al., Madrid, Spain. In Free Radic Biol Med, Jan 2016
During inflammation, leukocyte-derived eosinophil peroxidase catalyses the formation of hypobromous acid, which can brominate tyrosine residues in proteins to form bromotyrosine. Since eosinophils are involved in the pathogenesis of allergic reactions, such as asthma, urinary bromotyrosine level has been used for the assessment of children with asthma.
Eosinophil localization to the basement membrane zone is autoantibody- and complement-dependent in a human cryosection model of bullous pemphigoid.
Fairley et al., Iowa City, United States. In Exp Dermatol, Jan 2016
15HL-60 expression of granule protein [eosinophil derived neurotoxin (EDN) and eosinophil peroxidase (EPO)] mRNA and their degranulation in vitro was confirmed using RT-PCR and ELISA, respectively.
Nasal and Pharyngeal Eosinophil Peroxidase Levels in Adults with Poorly Controlled Asthma Correlate with Sputum Eosinophilia.
Lee et al., Hamilton, Canada. In Allergy, Jan 2016
UNASSIGNED: The objective of the study was to compare nasal, pharyngeal, and sputum eosinophil peroxidase (EPX) levels with induced sputum eosinophil percentage in 10 adults with poorly controlled asthma and 10 normal controls.
Peroxidase Enzymes Regulate Collagen Biosynthesis and Matrix Mineralization by Cultured Human Osteoblasts.
Evdokiou et al., Adelaide, Australia. In Calcif Tissue Int, Jan 2016
Released by infiltrating inflammatory cells, myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are heme-containing enzymes, whose functional involvement in bone repair has mainly been studied in the context of providing a mechanism for oxidative defense against invading microorganisms.
Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.
Evdokiou et al., Adelaide, Australia. In Int J Biochem Cell Biol, Nov 2015
Here we report for the first time that myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are readily internalised by human umbilical vein endothelial cells (HUVEC) where they promote cellular proliferation, migration, invasion, and stimulate angiogenesis both in vitro and in vivo.
Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis.
Powrie et al., Oxford, United Kingdom. In Immunity, Aug 2015
In addition to TNF secretion, release of eosinophil peroxidase promoted colitis identifying direct tissue-toxic mechanisms.
Detection of the halogenating activity of heme peroxidases in leukocytes by aminophenyl fluorescein.
Arnhold et al., Leipzig, Germany. In Free Radic Res, Jun 2015
This dye allows the detection of the halogenating activity in samples containing free myeloperoxidase and eosinophil peroxidase as well as in intact granulocytes using fluorescence spectroscopy and flow cytometry, respectively.
Purinergic P2Y12 Receptor Activation in Eosinophils and the Schistosomal Host Response.
Neves et al., Rio de Janeiro, Brazil. In Plos One, 2014
We found that adenosine 5'-diphosphate (ADP) induced human eosinophils to secrete eosinophil peroxidase (EPO) in a P2Y12R dependent manner.
Hepatic myofibroblasts derived from Schistosoma mansoni-infected mice are a source of IL-5 and eotaxin: controls of eosinophil populations in vitro.
Perez et al., Rio de Janeiro, Brazil. In Parasit Vectors, 2014
In a mixed co-culture system using GR-MF with hematopoietic bone marrow cells from infected mice, we observed eosinophil survival that was dependent upon IL-5 and eotaxin, since antibodies against this cytokines decreased eosinophil population, as measured by eosinophil peroxidase activity.
Eosinophil granule proteins: form and function.
Ackerman et al., Chicago, United States. In J Biol Chem, 2014
Studies using eosinophil-deficient mouse models, including eosinophil-derived granule protein double knock-out mice (major basic protein-1/eosinophil peroxidase dual gene deletion) show that eosinophils are required for all major hallmarks of asthma pathophysiology: airway epithelial damage and hyperreactivity, and airway remodeling including smooth muscle hyperplasia and subepithelial fibrosis.
Lactoperoxidase: structural insights into the function,ligand binding and inhibition.
Singh et al., New Delhi, India. In Int J Biochem Mol Biol, 2012
Lactoperoxidase (LPO) is a member of a large group of mammalian heme peroxidases that include myeloperoxidase (MPO), eosinophil peroxidase (EPO) and thyroid peroxidase (TPO).
Pattern-recognition receptors in human eosinophils.
Cardell et al., Stockholm, Sweden. In Immunology, 2012
Receptor stimulation induces survival, oxidative burst, activation of the adhesion system and release of cytokines (interleukin-1β, interleukin-6, tumour necrosis factor-α and granulocyte-macrophage colony-stimulating factor), chemokines (interleukin-8 and growth-related oncogene-α) and cytotoxic granule proteins (eosinophil cationic protein, eosinophil-derived neurotoxin, eosinophil peroxidase and major basic protein).
Bioluminescence imaging of myeloperoxidase activity in vivo.
Piwnica-Worms et al., Saint Louis, United States. In Nat Med, 2009
Bioluminescence colocalized with histological sites of inflammation and was totally abolished in gene-deleted Mpo(-/-) mice, despite massive tissue infiltration of neutrophils and activated eosinophils, indicating that eosinophil peroxidase did not contribute to luminol-BLI in vivo.
Mechanism of membrane damage mediated by human eosinophil cationic protein.
Cohn et al., In Nature, 1986
Several basic proteins have been isolated from eosinophil granules, including the major basic protein, eosinophil cationic protein, eosinophil protein-X and eosinophil peroxidase.
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