The corneal fibrosis response to epithelial-stromal injury.
Cleveland, United States. In Exp Eye Res, Jan 2016
A major discovery that has contributed to our understanding of haze development is that keratocytes and corneal fibroblasts produce critical EBM components, such as nidogen-1, nidogen-2 and perlecan, that are essential for complete regeneration of a normal EBM once laminin secreted by epithelial cells self-polymerizes into a nascent EBM.
Vitamin a deficiency and alterations in the extracellular matrix.
Burjassot, Spain. In Nutrients, 2014
Extracellular matrix proteins are among those whose synthesis is known to be modulated by vitamin A. Retinoic acid, the main biologically active form of vitamin A, influences the expression of collagens, laminins, entactin, fibronectin, elastin and proteoglycans, which are the major components of the extracellular matrix.
Role of apoptosis-inducing factor (Aif) in the T cell lineage.
New Delhi, India. In Indian J Med Res, 2013
In peripheral mature T cells, Aif deficiency leads to an increased susceptibility of T cell blasts to activation induced cell death (AICD), possibly mediated by its antioxidant function, and decreased sensitivity to neglect-induced death (NID).
[Mechanisms of programmed cell death of effector T lymphocytes].
Toruń, Poland. In Postepy Hig Med Dosw (online), 2012
Two main pathways of effector T cell PCD are discussed in the review: activation induced cell death (AICD), which is a form of extrinsic apoptosis, and neglect-induced death (NID), which is an intrinsic one.
Positioning of longitudinal nerves in C. elegans by nidogen.
United States. In Science, 2000
Although members of the nidogen (entactin) protein family are structural components of basement membranes, we find that nidogen is not required for basement membrane assembly in the nematode Caenorhabditis elegans.