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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Endothelial cell adhesion molecule

endothelial cell adhesion molecule-1, ESAM
Top mentioned proteins: CD31, HAD, CAN, Intercellular Adhesion Molecule-1, V1a
Papers on endothelial cell adhesion molecule-1
ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias.
Kanakura et al., Suita, Japan. In Exp Hematol, Feb 2016
We previously identified endothelial cell-selective adhesion molecule (ESAM) as a novel functional marker of hematopoietic stem cells in mice.
Expression of pro-angiogenic genes in mesenchymal stem cells derived from dermis of patients with psoriasis.
Zhang et al., Taiyuan, China. In Int J Dermatol, Feb 2016
Our microarray analysis suggested that the pro-angiogenic genes platelet endothelial cell adhesion molecule-1 (PECAM1), facio-genital dysplasia-5 (FGD5), prostaglandin-endoperoxide synthase-1 (PTGS1), melanoma cell adhesion molecule (MCAM), vasohibin-2 (VASH2), and stabilin-1 (STAB1) are differentially expressed in dermal mesenchymal stem cells in psoriasis.
PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling.
Jin et al., Rochester, United States. In Cell Signal, Jan 2016
Here we show that platelet endothelial cell adhesion molecule-1 (PECAM1), a key molecule in an endothelial mechanosensing complex, specifically mediates Gab1 tyrosine phosphorylation and its downstream Akt and eNOS activation in ECs upon flow rather than hepatocyte growth factor (HGF) stimulation.
The protective effect of melatonin on smoke-induced vascular injury in rats and humans: a randomized controlled trial (RCT).
Liu et al., Beijing, China. In J Pineal Res, Jan 2016
Melatonin decreased the expression of platelet endothelial cell adhesion molecule-1 (CD31), intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and endothelin-1 (ET-1) compared with the smoke exposed group (P < 0.05), whereas endothelial nitric oxide synthase (eNOS), nuclear erythroid 2-related factor 2 (Nrf2), NAD(P)H quinone oxidoreductase 1 (NQO-1), catalytic glutamate cysteine ligase (GCLC) and heme oxygenase-1 (HO-1) recovered markedly (P < 0.05).
Platelet endothelial cell adhesion molecule-1 (PECAM1) plays a critical role in the maintenance of human vascular endothelial barrier function.
Zhang et al., China. In Cell Biochem Funct, Dec 2015
This study aims to investigate the role of platelet endothelial cell adhesion molecule-1 (PECAM1) in the maintenance of the vascular endothelial barrier integrate.
Involvement of phosphoinositide 3-kinase class IA (PI3K 110α) and NADPH oxidase 1 (NOX1) in regulation of vascular differentiation induced by vascular endothelial growth factor (VEGF) in mouse embryonic stem cells.
Wartenberg et al., Jena, Germany. In Cell Tissue Res, Dec 2015
Silencing p110α or inhibiting Rac1 arrests vasculogenesis at initial stages in embryoid bodies, even under VEGF treatment, as indicated by platelet endothelial cell adhesion molecule-1 (PECAM-1)-positive areas and branching points.
Monocyte trafficking across the vessel wall.
Ley et al., Los Angeles, United States. In Cardiovasc Res, Sep 2015
The emerging roles of endothelial junctional molecules like vascular endothelial-cadherin and the junctional adhesion molecule family, adhesion molecules such as intercellular adhesion molecule-1, molecules localized to the lateral border recycling compartment like cluster of differentiation 99, platelet/endothelial cell adhesion molecule-1, and poliovirus receptor (CD155), as well as other cell surface molecules such as cluster of differentiation 146 and ephrins in transendothelial migration are discussed.
PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis.
Sheibani et al., Madison, United States. In Clin Sci (lond), Aug 2015
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31), a cell adhesion molecule with proangiogenic and proinflammatory activity, has been the subject of numerous studies.
The IgCAMs CAR, BT-IgSF, and CLMP: structure, function, and diseases.
Rathjen et al., In Adv Neurobiol, 2013
The coxsackie-adenovirus receptor (CAR) is the prototype of a small subfamily of IgCAMs composed of CAR itself, CLMP, BT-IgSF, ESAM, CTX, and A33.
Association of single nucleotide polymorphisms in the gene encoding platelet endothelial cell adhesion molecule-1 with the risk of myocardial infarction: a systematic review and meta-analysis.
Golledge et al., Mashhad, Iran. In Thromb Res, 2013
BACKGROUND: Single nucleotide polymorphisms (SNPs) within the platelet endothelial cell adhesion molecule-1 (PECAM-1) gene have been proposed as predisposing factors for myocardial infarction (MI) but published reports have given conflicting findings.
The role of the tumor endothelium in leukocyte recruitment in pancreatic cancer.
Ryschich et al., Heidelberg, Germany. In Surgery, 2012
RESULTS: The leukocyte extravasation in normal pancreas during acute pancreatitis follows the "classic" leukocyte recruitment cascade and is controlled by the overexpression of endothelial adhesion molecules, such as selectins, intracellular adhesion molecule-1, and platelet endothelial cell adhesion molecule-1.
The endothelial antigen ESAM monitors hematopoietic stem cell status between quiescence and self-renewal.
Kanakura et al., Suita, Japan. In J Immunol, 2012
ESAM levels clearly mirror the shift of hematopoietic stem cells (HSC) between quiescence and activation, and the intensity of expression is prominent in comparison with other HSC-related antigens.
Endothelial cell-selective adhesion molecule modulates atherosclerosis through plaque angiogenesis and monocyte-endothelial interaction.
Hirata et al., Kōbe, Japan. In Microvasc Res, 2010
ESAM inactivation can reduce susceptibility to atherosclerosis by inhibiting plaque neovascularization and macrophage infiltration into the atheroma.
Role of endothelial cell-selective adhesion molecule in hematogeneous metastasis.
Hayashi et al., Kōbe, Japan. In Microvasc Res, 2010
ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules.
Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivo.
Brass et al., Philadelphia, United States. In J Thromb Haemost, 2009
findings support a model in which ESAM localizes to platelet contacts following platelet activation in order to limit thrombus growth and stability
Differential associations between soluble cellular adhesion molecules and atherosclerosis in the Dallas Heart Study: a distinct role for soluble endothelial cell-selective adhesion molecule.
de Lemos et al., Dallas, United States. In Arterioscler Thromb Vasc Biol, 2009
sESAM is a predictive biomarker and potential mediator of atherosclerosis.
Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury.
Muzykantov et al., Saint Louis, United States. In Nat Biotechnol, 2003
Intravenously injected enzymes, conjugated with an antibody to platelet-endothelial cell adhesion molecule-1, accumulate in the pulmonary vasculature and retain their activity during prolonged cold storage and transplantation.
Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment.
Savill et al., Edinburgh, United Kingdom. In Nature, 2002
Here we propose that CD31 (also known as platelet-endothelial cell adhesion molecule-1, PECAM-1) is an example of a cell-surface molecule that prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and which changes function on apoptosis, promoting tethering of dying cells to phagocytes.
PECAM-1/CD31, an endothelial receptor for binding Plasmodium falciparum-infected erythrocytes.
Wahlgren et al., Stockholm, Sweden. In Nat Med, 1997
Here we report that malaria-infected RBCs adhere to platelet/endothelial cell adhesion molecule-1 (PECAM-1/CD31) on the vascular endothelium.
Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo.
Albelda et al., Ann Arbor, United States. In Science, 1994
In vitro assays have suggested that platelet-endothelial cell adhesion molecule-1 [PECAM-1 (CD31)], a member of the immunoglobulin superfamily, is required for the transmigration of neutrophils across endothelial monolayers.
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