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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

SH3-domain GRB2-like 2

endophilin, endophilin 1, endophilin I, SH3p4, SH3GL2
interacts with synaptojanin and dynamin I; may be involved in synaptic vesicle recycling [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: Dynamin I, beta 2-adrenoceptor, Amphiphysin, Src, V1a
Papers using endophilin antibodies
Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains
Qualmann Britta et al., In The Journal of Cell Biology, 1997
... The rat endophilin SH3 domain was cloned from a rat brain cDNA library (MATCHMAKER in pGAD10; CLONTECH Laboratories, Inc.) by PCR ...
Papers on endophilin
CPG2 Recruits Endophilin B2 to the Cytoskeleton for Activity-Dependent Endocytosis of Synaptic Glutamate Receptors.
Nedivi et al., Cambridge, United States. In Curr Biol, Feb 2016
Here, we show that CPG2, through a direct physical interaction, recruits endophilin B2 (EndoB2) to F-actin, thus anchoring the endocytic machinery to the spine cytoskeleton and facilitating glutamate receptor internalization.
Plectin isoform 1-dependent nuclear docking of desmin networks affects myonuclear architecture and expression of mechanotransducers.
Wiche et al., Vienna, Austria. In Hum Mol Genet, Jan 2016
Mechanistically, P1 is shown to specifically interact with the myonuclear membrane-associated (BAR domain-containing) protein endophilin B. Our results open a new perspective on cytoskeleton-nuclear crosstalk via specific cytolinker proteins.
Regulation of membrane-shape transitions induced by I-BAR domains.
Baumgart et al., Philadelphia, United States. In Biophys J, Aug 2015
We find that the curvature generation capacity of IMDs is significantly stronger compared to that of endophilin, an N-BAR protein known to be involved in plasma membrane shape transitions.
Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis.
Johannes et al., Paris, France. In Nature, Feb 2015
In the clathrin pathway, dynamin uses mechanical energy from GTP hydrolysis to this effect, assisted by the BIN/amphiphysin/Rvs (BAR) domain-containing protein endophilin.
Endophilin marks and controls a clathrin-independent endocytic pathway.
McMahon et al., Cambridge, United Kingdom. In Nature, Feb 2015
Endophilin has been assigned as a component of clathrin-mediated endocytosis.
High-Throughput All-Optical Analysis of Synaptic Transmission and Synaptic Vesicle Recycling in Caenorhabditis elegans.
Gottschalk et al., Frankfurt am Main, Germany. In Plos One, 2014
Mutation of genes affecting SV recycling (unc-26 synaptojanin, unc-41 stonin, unc-57 endophilin, itsn-1 intersectin, snt-1 synaptotagmin) showed a distinct 'signature' of muscle Ca2+ dynamics, induced by cholinergic motoneuron photostimulation, i.e. faster rise, and earlier decrease of the signal, reflecting increased synaptic fatigue during ongoing photostimulation.
Distinct Functions of Endophilin Isoforms in Synaptic Vesicle Endocytosis.
Chen et al., Guangzhou, China. In Neural Plast, 2014
Endophilin isoforms perform distinct characteristics in their interactions with N-type Ca(2+) channels and dynamin.
Lipid cell biology. Polyunsaturated phospholipids facilitate membrane deformation and fission by endocytic proteins.
Barelli et al., Antibes, France. In Science, 2014
Here, we found that polyunsaturated PLs increased the ability of dynamin and endophilin to deform and vesiculate synthetic membranes.
Regulating dynamin dynamics during endocytosis.
Hinshaw et al., Bethesda, United States. In F1000prime Rep, 2013
Three of these dynamin-binding partners (intersectin, amphiphysin and endophilin) have been shown to play important roles in the clathrin-mediated endocytosis process.
The function of endocytosis in podocytes.
Ishibe et al., New Haven, United States. In Curr Opin Nephrol Hypertens, 2013
Recent evidence suggests that loss of key clathrin endocytic regulatory apparatus, such as dynamin, synaptojanin 1 or endophilin, in genetic mouse models of disease results in severe proteinuria and foot process effacement.
Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules.
Zheng et al., Beijing, China. In J Biol Chem, 2012
Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
Nonlinear sorting, curvature generation, and crowding of endophilin N-BAR on tubular membranes.
Baumgart et al., Philadelphia, United States. In Biophys J, 2012
measurements of curvature sorting and curvature generation of the endophilin A1 N-BAR domain on tubular membranes pulled from giant unilamellar vesicles
Membrane fission is promoted by insertion of amphipathic helices and is restricted by crescent BAR domains.
Kozlov et al., Cambridge, United Kingdom. In Cell, 2012
We also show that BAR-domain scaffolds from endophilin, amphiphysin, GRAF, and β2-centaurin limit membrane fission driven by hydrophobic insertions.
Structural basis of membrane bending by the N-BAR protein endophilin.
Unger et al., Evanston, United States. In Cell, 2012
Using electron cryomicroscopy, we present reconstructions of full-length endophilin and its N-terminal N-BAR domain in their membrane-bound state.
Barfly: sculpting membranes at the Drosophila neuromuscular junction.
Robinson et al., Cleveland, United States. In Dev Neurobiol, 2012
In flies the BAR domain containing proteins, endophilin and syndapin affect synaptic vesicle endocytosis, whereas CIP4, dRich, nervous wreck and syndapin affect synaptic morphology.
Retrolinkin cooperates with endophilin A1 to mediate BDNF-TrkB early endocytic trafficking and signaling from early endosomes.
Liu et al., Beijing, China. In Mol Biol Cell, 2011
retrolinkin is a binding partner of endophilin A1 and that both proteins are required for BDNF-induced dendrite outgrowth
The structure and function of endophilin proteins.
Jung et al., Copenhagen, Denmark. In Cell Biochem Biophys, 2011
Here, we discuss the role of endophilins in these processes and summarize novel insights into the molecular aspects of endophilin function.
Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin.
Low et al., Singapore, Singapore. In Plos One, 2010
simulations constitute a multi-dimensional exploration of how EGF-dependent EGFR endocytosis and ERK activation are dynamically affected by scaffolds KSR and MP1, co-regulated by Cbl-CIN85 and Endophilin A1
[Lipids in the process of synaptic vesicle exo- and endocytosis].
Petrov et al., In Ross Fiziol Zh Im I M Sechenova, 2010
The SNARE-complex forming proteins (synaptobrevin, syntaxin, SNAP-25), synaptotagmin, Munc13, Munc18, NSF, alpha-SNAP are involved in exocytosis, while the synaptic vesicle endocytosis is mediated by another protein (clathrin, AP-2, epsin, endophilin, amphiphysin, dynamin, synaptojanin, Hsc70).
SH3GL2 gene participates in MEK-ERK signal pathway partly by regulating EGFR in the laryngeal carcinoma cell line Hep2.
Sun et al., Shenyang, China. In Med Sci Monit, 2010
SH3GL2 participates in the regulation of apoptosis through the MEK-ERK signal pathway by adjusting EGFR in the laryngeal carcinoma cell line Hep2
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