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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.


Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, V1a, fibrillin-1
Papers using EMD antibodies
Stable IgG-like bispecific antibodies directed toward the type I Insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity
Han Zhaozhong, In PLoS ONE, 2010
... PhosphoSafe Extraction Reagent and RIPA buffer used for cell lysis were obtained from EMD Biosciences and Cell Signaling, respectively ...
Chronic intermittent hypobaric hypoxia decreases beta-adrenoceptor activity in right ventricular papillary muscle. Am J Physiol Heart Circ Physiol
Chen Xiongwen, In PLoS ONE, 2009
... as follows: isoproterenol hydrochloride (Sigma-Aldrich, St.Louis, MO, USA), G-1 (EMD Chemicals, San Diego, CA, USA), G15(EMD Chemicals, San Diego, CA, USA), 17β-estradlol (ABCR, Germany), ICI118551 (tocris, Bristol, UK), CGP20712A (Sigma-Aldrich, ...
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
Yoshimori Tamotsu et al., In The Journal of Cell Biology, 2008
... Leukemia inhibitory factor (EMD) on plastic plates coated with 0.1% gelatin (Wako Chemicals USA, Inc.) ...
Association of simian virus 40 vp1 with 70-kilodalton heat shock proteins and viral tumor antigens.
Galloway Denise, In PLoS Pathogens, 2008
... antibodies against PDI from Abcam, large T antigen from Santa Cruz Biotechnology, MG132 and epoxomicin from EMD chemicals, BFA from Epicenter, proteinase K and monoclonal antibodies against HA from Roche, and TCEP from Thermo Scientific.
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
van der Bliek Alexander M. et al., In The Journal of Cell Biology, 2007
... Apoptosis was induced with 2 µM staurosporine (Sigma-Aldrich) or 20 µM actinomycin D (EMD) with 200 µM zVAD-fmk (MP Biomedicals) added 30 min before ...
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Papers on EMD
Molecular characterization and expression patterns of emerin (EMD) gene in skeletal muscle between Meishan and Large White pigs.
Wang et al., Chengdu, China. In Gene, Apr 2016
In this study, we cloned and characterized the pig emerin (EMD) gene.
Enamel Matrix Derivative Promotes Healing of a Surgical Wound in the Rat Oral Mucosa.
Weinreb et al., Tel Aviv-Yafo, Israel. In J Periodontol, Feb 2016
Sporadic clinical observations of periodontal regeneration treatments with Enamel Matrix Derivative (EMD), a commercial formulation of EMPs, suggest it also promotes post-surgical healing of soft tissues.
Gene array of PDL cells exposed to Osteogain in combination with a bone grafting material.
Zhang et al., Québec, Canada. In Clin Oral Investig, Feb 2016
OBJECTIVES: The aim of the present study was to investigate the effects of Osteogain, a new formulation of enamel matrix derivative (EMD) in combination with a grafting material on a wide variety of genes for cytokines, transcription factors and extracellular matrix proteins involved in osteoblast differentiation.
High nuclear expression of Twist1 in the skeletal extramedullary disease of myeloma patients predicts inferior survival.
Zhang et al., Shijiazhuang, China. In Pathol Res Pract, Jan 2016
UNASSIGNED: The aim of the study was to investigate the expression of epithelial to mesenchymal transition (EMT)-inducing transcription factors, including Twist1 and ZEB1, in skeletal extramedullary disease (EMD) of multiple myeloma (MM) patients and to clarify the effects on clinical outcomes.
Generation and periodontal differentiation of human gingival fibroblasts-derived integration-free induced pluripotent stem cells.
Luan et al., Beijing, China. In Biochem Biophys Res Commun, Nov 2015
Furthermore, treatment of the iPSCs in vitro with enamel matrix derivative (EMD) or growth/differentiation factor-5 (GDF-5) significantly up-regulated the expression of periodontal tissue markers associated with bone, periodontal ligament and cementum respectively.
The Influence of Arginine on the Response of Enamel Matrix Derivative (EMD) Proteins to Thermal Stress: Towards Improving the Stability of EMD-Based Products.
Månson et al., Lausanne, Switzerland. In Plos One, 2014
In a current procedure for periodontal tissue regeneration, enamel matrix derivative (EMD), which is the active component, is mixed with a propylene glycol alginate (PGA) gel carrier and applied directly to the periodontal defect.
The role of adipokines in periodontal infection and healing.
Nokhbehsaim et al., Bonn, Germany. In Mol Oral Microbiol, 2014
To achieve regenerative periodontal healing, bioactive molecules, such as enamel matrix derivative (EMD), are applied during periodontal surgery.
Enamel matrix derivative, inflammation and soft tissue wound healing.
Weinreb et al., Bern, Switzerland. In J Periodontal Res, 2014
Over 15 years have now passed since enamel matrix derivative (EMD) emerged as an agent capable of periodontal regeneration.
Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial.
ATAMS Study Group et al., Basel, Switzerland. In Lancet Neurol, 2014
FUNDING: Merck Serono (Merck KGaA) and EMD Serono (Merck KGaA).
[The multiple myeloma--current view and perspectives].
Knop, In Med Monatsschr Pharm, 2014
Among all patients those with extramedullary disease (EMD) are currently the most difficult treatable patients.
Emery-Dreifuss humeroperoneal muscular dystrophy: cardiac manifestations.
Parmar et al., Thunder Bay, Canada. In Can J Cardiol, 2012
Genetic testing identified the mutation in the EMD gene, confirming X-linked recessive (XR) EDMD. The patient's asymptomatic mother was confirmed as a carrier.
The nuclear envelope protein emerin binds directly to histone deacetylase 3 (HDAC3) and activates HDAC3 activity.
Holaska et al., Chicago, United States. In J Biol Chem, 2012
emerin facilitates repressive chromatin formation at the nuclear periphery by increasing the catalytic activity of HDAC
Loss of emerin alters myogenic signaling and miRNA expression in mouse myogenic progenitors.
Holaska et al., Chicago, United States. In Plos One, 2011
report significant perturbations in the expression and activation of p38/Mapk14 in emerin-null myogenic progenitors, showing that perturbed expression of Wnt, IGF-1, TGF-beta, and Notch signaling components disrupts normal downstream myogenic signaling
Novel and recurrent EMD mutations in patients with Emery-Dreifuss muscular dystrophy, identify exon 2 as a mutation hot spot.
Ellis et al., Durham, United States. In J Hum Genet, 2011
Data augment the number of EMD mutations by 13.8%, equating to an increase of 5.2% in the total known EMD mutations and to an increase of 6.0% in the number of different mutations.
Structural protein 4.1R is integrally involved in nuclear envelope protein localization, centrosome-nucleus association and transcriptional signaling.
Krauss et al., Berkeley, United States. In J Cell Sci, 2011
Data provide evidence that 4.1R has functional interactions with emerin and A-type lamin that impact upon nuclear architecture, centrosome-nuclear envelope association and the regulation of beta-catenin transcriptional co-activator activity.
Phase I clinical trial of the immunocytokine EMD 273063 in melanoma patients.
Sondel et al., Madison, United States. In J Clin Oncol, 2004
PURPOSE: To evaluate the safety, toxicity, in vivo immunologic activation, and maximum-tolerated dose (MTD) of EMD 273063 (hu14.18-IL-2) in patients with metastatic melanoma.
Extramedullary involvement at relapse in acute promyelocytic leukemia patients treated or not with all-trans retinoic acid: a report by the Gruppo Italiano Malattie Ematologiche dell'Adulto.
Mandelli et al., Bari, Italy. In J Clin Oncol, 2001
PURPOSE: Recent reports of extramedullary disease (EMD) at recurrence in acute promyelocytic leukemia (APL) have raised increasing concern about a possible role of retinoic acid (RA) therapy.
Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy.
Schwartz et al., Paris, France. In Nat Genet, 1999
Mutations in EMD, the gene encoding emerin, are responsible for the X-linked form.
Emerin deletion reveals a common X-chromosome inversion mediated by inverted repeats.
Warren et al., Atlanta, United States. In Nat Genet, 1997
Emery-Dreifuss muscular dystrophy (EMD) is an X-linked disorder characterized by contractures, progressive muscle weakness and cardiomyopathy.
Sutton et al., Southampton, United Kingdom. In Unknown Journal, 0001
RESULTS: Phase 1: for patients with a final diagnosis of stroke, facial weakness and speech problems were significantly associated with an EMD code of stroke.
More papers using EMD antibodies
Cyanidin-3-O-β-glucoside inhibits iNOS and COX-2 expression by inducing liver X receptor alpha activation in THP-1 macrophages
Galvano Fabio et al., In Toxins, 2007
... was from SantaCruz Biotechnology (Santa Cruz, CA, USA), goat polyclonal DDAH-1 antibody was from Calbiochem EMD Biosciences, Inc., an affiliate of Merck KGaA (Darmstadt, Germany), anti-actin ...
Transferrin receptor 2: evidence for ligand-induced stabilization and redirection to a recycling pathway.
Wölfl Stefan, In PLoS ONE, 2006
... In select experiments we pretreated 1° cells with MG 132 (EMD), Bafilomycin A (PKC Pharmaceuticals), Ammonium Chloride (Fisher), Chloroquine (Sigma), AZT (Sigma), Latrunculin A and B (Biomol).
uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells
You Shaojin et al., In Breast Cancer Research : BCR, 2006
... RU486 (mifepristone), AG1498, wortmannin, PP1 and PD98052 were purchased from EMD Chemicals (Gibbstown, NJ, USA); R5020 (promegestone) and bpV (phen) were from PerkinElmer (Waltham, MA, USA) and ...
Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice
Dolmetsch Ricardo E. et al., In The Journal of Cell Biology, 2006
... Alomone Labs; DL-AP3 was purchased from Tocris Bioscience; bafilomycin A1 and lactacystin were purchased from EMD; chloroquine was purchased from MP Biomedicals; biotin–deoxy-UTP was purchased from ...
Pre-processing Agilent microarray data
Ciardiello F et al., In British Journal of Cancer, 2006
... provided by Bayer Schering Pharma, Leverkusen, Germany; MSC19363669B (formerly known as AS703026) was provided by EMD Serono, Rockland, MA, USA; deguelin was ...
Tilescope: online analysis pipeline for high-density tiling microarray data.
Copenhaver Gregory P., In PLoS Genetics, 2006
... Santa Cruz Biotechnology, sc-17796; 5) anti-lamin A/C (H-110), Santa Cruz Biotechnology, sc-20681; 6) anti-lamin B antibody, EMD Biosciences, NA12; or 7) normal IgG, Santa Cruz Biotechnology, sc-2025 ...
Mechanotransduction in an extracted cell model: Fyn drives stretch- and flow-elicited PECAM-1 phosphorylation
Fujiwara Keigi et al., In The Journal of Cell Biology, 2006
... (Invitrogen), collagen type I (BD Biosciences), genistein (EMD), LFM-A13 (EMD), SU6656 (EMD), VEGFR kinase inhibitor (3-(3-Thienyl)-6-(4-methoxyphenyl)pyrazolopyrimidine; EMD), and PP2 (Tocris Bioscience) ...
Inhibition of GSK-3beta mediates expression of MMP-9 through ERK1/2 activation and tr-anslocation of NF-kappaB in rat primary astrocyte
Han Seol-Heui et al., In Journal of Clinical Neurology (Seoul, Korea), 2006
... PD98059 (PD) and SB203580 (SB) were purchased from Calbiochem, EMD Biosciences (La Jolla, CA, USA), and SP600125 (SP) and Trolox were purchased from Biomol (Plymouth Meeting, PA, USA) ...
The interaction between αA- and αB-crystalllin is sequence-specific.
Srivastava O.P. et al., In Molecular Vision, 2005
... L) horseradish peroxidase-conjugated secondary antibody were obtained from Calbiochem-EMD Biosciences (La Jolla, CA) and Thermo Scientific (Rockford, IL), respectively ...
Lining the pockets of kinases and phosphatases
Vaughan Roxanne A. et al., In The Journal of Biological Chemistry, 2005
... protein A-Sepharose beads were from GE Healthcare; PMA, OA, recombinant PKCα, and ERK1 were from EMD Calbiochem; goat anti-DAT polyclonal antibody (C-20) was from Santa Cruz Biotechnology, Inc ...
Comprehensive algorithm for quantitative real-time polymerase chain reaction.
Homayouni Ramin, In PLoS ONE, 2004
... Bovine serum albumin (BSA) fraction V was obtained from EMD (Gibbstown, NJ), instant non-fat dry milk was purchased at a local grocery store, and methanol was purchased from Sigma Aldrich.
Assisted reproductive technology success rates
Patrizio Pasquale et al., In Journal of Experimental & Clinical Assisted Reproduction, 2004
... , EMD Serono, Inc., Rockland, MA), and reduction of ...
A genetic mechanism implicates chromosome 11 in schizophrenia and bipolar diseases
Hashimoto Kenji, In PLoS ONE, 2003
... For immunohistochemistry, free-floating sections were labeled with a rabbit anti-c-Fos primary antibody (dilution 1∶10,000; Ab-5; Calbiochem/EMD, San Diegeo, CA, USA), detected using Vectastain Elite ABC reagents (Vector Laboratories, Burlingame, CA, USA) with ...
Activation of Gαi3 triggers cell migration via regulation of GIV
Farquhar Marilyn G. et al., In The Journal of Cell Biology, 2003
... Antibodies against Gαs and Gαi3 were obtained from EMD, and pan Gβ (M-14) and Gαi3 used for immunoblotting were purchased from Santa Cruz Biotechnology, Inc ...
Strategy for the development of novel anticancer drugs
Chen P. et al., In International Journal of Nanomedicine, 2002
... The anticancer drug, ellipticine (98% purity), was purchased from EMD-Merck (Mississauga, Canada).
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.
Calbet Jose, In PLoS ONE, 2000
... H-89 or 8-br-cAMP (EMD Biosciences) were dissolved in sterile water; U73122, ionomycin (both EMD Biosciences), butaprost, or CAY10580 (both Cayman Chemical) were dissolved in ...
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
Harbour J. William et al., In Oncogene, 1999
... Cdk2 inhibitor (Roscovitine, Sigma Aldrich), Cdk4 inhibitor (EMD, Darmstadt, Germany), Hdm2 E3 Ligase Inhibitor 373225 (EMD), Z-VAD-FMK (Sigma Aldrich) or MG132 (Sigma Aldrich) ...
Extracellular metabolism of ATP and other nucleotides
Bergersen L. H. et al., In The European Journal of Neuroscience, 1999
... Secondary antibody, goat anti-rabbit IgG-HRP conjugate, was from Calbiochem (EMD Biosciences, affiliate of Merck kgaA, Darmstadt, Germany) ...
Chronic myeloid leukemia
Combs Colin K et al., In Journal of Neuroinflammation, 1998
... Anti-phosphotyrosine (4G10) antibody was from EMD Millipore (Billerica, MA, USA) and anti-pLyn (Tyr 396) antibody was purchased from Abcam (Cambridge, MA, USA) ...
Heat shock transcription factor-1 regulates heat shock protein-72 expression in human keratinocytes exposed to ultraviolet B light.
Kleeberger Steven R. et al., In Environmental Health Perspectives, 1997
... -exposed OuJ and HeJ mice using a specific HSP70 antibody (EMD Chemicals, Gibbstown, NJ) and a labeled streptavidin-biotin (LSAB) secondary antibody (DAKO, Carpinteria, CA) ...
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.
Cordes Nils, In PLoS ONE, 1997
... some experiments, the monolayers were pre-incubated for 60 minutes with 10 µM of PP3, PP2 (EMD-Calbiochem) or U0126 (Cell Signaling) and scratched wounded in ...
Expression of eukaryotic proteins in soluble form in Escherichia coli
Shelp Barry J. et al., In Journal of Experimental Botany, 1997
... (PCR) products (1039 and 910 bp, respectively) were cloned into the pET-15b expression vector (Novagen, EMD Biosciences Inc., Madison, WI, USA) and sent to Genologics (University of Guelph, Laboratory Services Branch, Guelph, ON, Canada) for sequencing (ABI PRISM Sequencer Model 377, PerkinElmer Life Sciences, Foster City, ...
Functional domains of the nuclear receptor hepatocyte nuclear factor 4
Jin Dong-Yan, In PLoS ONE, 1996
... Thapsigargin (Calbiochem EMD Millipore, Billerica, MA) at 500 nM final and Sal003 (Santa Cruz Biotechnology, Santa Cruz, CA) at ...
Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F β-amyloid precursor protein and Alzheimer's disease.
Kallas Esper Georges, In PLoS ONE, 1995
... Ryanodine was purchased from Calbiochem (EMD Biosciences, La Jolla, CA) and dantrolene was purchased from Tocris (Ellisville, MO) ...
Sepsis stimulates polyamine biosynthesis in the liver and increases tissue levels of ornithine decarboxylase mRNA
Laub M et al., In European Journal of Medical Research, 1994
... For chromatographic application fractogel EMD-DEAE 650 (s) and TSK HW-65 (s) Merck (Darmstadt) were used ...
Localization of Giα proteins in the centrosomes and at the midbody: implication for their role in cell division
Kehrl John H. et al., In The Journal of Cell Biology, 1993
... from EMD Biosciences; and monoclonal anti-Giα1 and -Giα2 and polyclonal anti-Giα3 from Santa Cruz Biotechnology, Inc ...
Deamidation of human erythrocyte protein 4.1: possible role in aging.
Srivastava O.P. et al., In Molecular Vision, 1991
... L) horseradish peroxidase-conjugated secondary antibody were obtained from Calbiochem-EMD Biosciences (La Jolla, CA) and Thermo Scientific (Rockford, IL), respectively ...
Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli.
Picardeau Mathieu, In PLoS Neglected Tropical Diseases, 1990
... Louis, MO (ampicillin, chloramphenicol, erythromycin, kanamycin, polymyxin B and streptomycin), EMD Biosciences, San Diego, CA (gentamicin), Invitrogen, Carlsbad, CA (zeocin) or Biomol via VWR International, West ...
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
Cooper G M et al., In Cell Death & Disease, 1989
... M, EMD Biosciences, San Diego, CA, USA), SB-216763 (5 μM, Biomol, Hamburg, Germany) or actinomycin ...
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors.
Morty Rory Edward, In PLoS ONE, 1983
... Stock solutions of the Chk1 inhibitors UCN-01 (EMD Biosciences, San Diego, CA) and AZD7762 (Selleck Chemical), HDACis scriptaid (BioMol International, Plymouth Meeting, PA), ...
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction.
Janda Kim D., In PLoS ONE, 1972
... S]GTPγS assay were purchased from EMD Chemical (Gibbstown, NJ), and Sigma Aldrich (St ...
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