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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

AT hook containing transcription factor 1

ELYS, putative transcription factor SOX13, Putative Transcription Factor, putative transcription factor TCP16
Top mentioned proteins: Nucleoporin, Mel, CAN, Adenylate Cyclase, RAN
Papers on ELYS
Nucleosome functions in spindle assembly and nuclear envelope formation.
Funabiki et al., New York City, United States. In Bioessays, Oct 2015
Both processes require the generation of RanGTP by RCC1 recruited to nucleosomes but nucleosomes also acquire cell cycle stage specific regulators, Aurora B in mitosis and ELYS, the initiator of nuclear pore complex assembly, at mitotic exit.
Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos.
Blow et al., Dundee, United Kingdom. In Cell Rep, Aug 2015
Upon replication initiation, the CDC-45-MCM-GINS (CMG) DNA helicase drives the release of condensin I complexes from chromatin and the activation or displacement of inactive MCM-2-7 complexes, which together with the nucleoporin MEL-28/ELYS tethers condensed chromatin to the nuclear envelope, thereby promoting chromatin decondensation.
Intranuclear dynamics of the Nup107-160 complex.
Doye et al., Paris, France. In Mol Biol Cell, Jul 2015
Here we show that the mammalian Nup107-160 complex (Y-complex), a major scaffold module of the nuclear pore, together with its partner Elys, colocalizes with Nup98 in GLFG bodies.
SINC, a type III secreted protein of Chlamydia psittaci, targets the inner nuclear membrane of infected cells and uninfected neighbors.
Bavoil et al., Baltimore, United States. In Mol Biol Cell, Jun 2015
This strategy identified 22 candidates with high confidence, including the nucleoporin ELYS, lamin B1, and four proteins (emerin, MAN1, LAP1, and LBR) of the inner nuclear membrane, suggesting that SINC interacts with host proteins that control nuclear structure, signaling, chromatin organization, and gene silencing.
A Putative Transcription Factor pcs1 Positively Regulates Both Conidiation and Sexual Reproduction in the Cereal Pathogen Fusarium graminearum.
Lee et al., Pusan, South Korea. In Plant Pathol J, 2014
The plant pathogen Fusarium graminearum causes Fusarium head blight in cereal crops and produces mycotoxins that are harmful to animals and humans.
Nucleosomal regulation of chromatin composition and nuclear assembly revealed by histone depletion.
Funabiki et al., New York City, United States. In Nat Struct Mol Biol, 2014
We show that, in addition to the Ran G-nucleotide exchange factor RCC1, ELYS, the initiator of NPC formation, fails to associate with naked DNA but directly binds histone H2A-H2B dimers and nucleosomes.
Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration.
Forbes et al., Dallas, United States. In Mol Biol Cell, 2014
ELYS and the nucleoporin 107-160 complex, components of mitotic kinetochores and nuclear pores, are blocked from binding to kinetochores in vitro by transportin, a block reversible by M9M.
The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation.
Gruss et al., Heidelberg, Germany. In Nat Commun, 2013
The nucleoporin MEL-28/ELYS binds chromatin in a RanGTP-regulated manner and acts to seed NPC assembly.
Protein interfaces of the conserved Nup84 complex from Chaetomium thermophilum shown by crosslinking mass spectrometry and electron microscopy.
Hurt et al., Heidelberg, Germany. In Structure, 2013
This assembly carries Nup37 and Elys, which are characteristic subunits of the orthologous human Nup107-Nup160 complex but absent from the yeast Saccharomyces cerevisiae.
Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex.
Schwartz et al., Cambridge, United States. In Proc Natl Acad Sci U S A, 2012
To unravel the basic scaffold underlying the NPC, we have characterized the species-specific scaffold nucleoporin Nup37 and ELY5/ELYS.
The nucleoporin ELYS/Mel28 regulates nuclear envelope subdomain formation in HeLa cells.
Imamoto et al., Saitama, Japan. In Nucleus, 2012
ELYS/Mel28 plays a role in NE subdomain formation in late mitosis
Dissection of the NUP107 nuclear pore subcomplex reveals a novel interaction with spindle assembly checkpoint protein MAD1 in Caenorhabditis elegans.
Askjaer et al., Sevilla, Spain. In Mol Biol Cell, 2012
In contrast, NPP-5 is essential for proper kinetochore localization of NUP133/NPP-15, another NUP107 complex member, whereas recruitment of NUP96/NPP-10C and ELYS/MEL-28 is NPP-5 independent.
A dominant-negative form of POM121 binds chromatin and disrupts the two separate modes of nuclear pore assembly.
Harel et al., Haifa, Israel. In J Cell Sci, 2011
The soluble POM121 fragment binds chromatin at sites that are distinct from ELYS-Nup107-160 'seeding' sites and prevents membrane enclosure and NPC formation.
The nuclear pore complex protein Elys is required for genome stability in mouse intestinal epithelial progenitor cells.
Pack et al., Philadelphia, United States. In Gastroenterology, 2011
In mice, Elys maintains genome stability in intestinal epithelial progenitor cells, independent of its role in NPC assembly in zebrafish.
Nuclear pore formation but not nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase.
Imamoto et al., Wako, Japan. In Nat Struct Mol Biol, 2010
Consistent with this, Cdk inhibition disturbed proper expression and localization of some nucleoporins, including Elys/Mel-28, which triggers postmitotic NPC assembly.
The zebrafish flotte lotte mutant reveals that the local retinal environment promotes the differentiation of proliferating precursors emerging from their stem cell niche.
Wilson et al., London, United Kingdom. In Development, 2010
Results suggest that the flo gene product, Elys, is dispensable for maintaining a stem cell-like state, but is important for the transition from proliferation to differentiation.
Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish.
Heath et al., Melbourne, Australia. In Gastroenterology, 2009
Elys regulates digestive organ formation
ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division.
Forbes et al., San Diego, United States. In Proc Natl Acad Sci U S A, 2006
Results suggets that ELYS is an unexpected member of the nuclear pore and kinetochore that functions in both pore assembly at the nucleus and faithful cell division.
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