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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

EP300 interacting inhibitor of differentiation 1

EID1, CRII, CRI1, E1A-like inhibitor of differentiation-1
EID1 is an F-box protein that functions as a negative regulator in phytochrome A (phyA)-specific light signalling. Expressed at all stages of plant development independently of light conditions, localizes to the nucleus, and forms nuclear speckles under continuous far-red light. Forms stable dimeric and trimeric complexes with several ASK proteins and Cullin1 in yeast and in planta. (from NCBI)
Top mentioned proteins: E1A, CAN, p300, ACID, Histone
Papers on EID1
Regulation of human subcutaneous adipocyte differentiation by EID1.
Lizcano et al., Maebashi, Japan. In J Mol Endocrinol, Feb 2016
The objective of this study was to determine the function of EP300-interacting inhibitor of differentiation (EID1), an inhibitor of muscle differentiation, in the induction of beige adipocytes from adipose mesenchymal stem cells (ADMSCs).
Domestication selected for deceleration of the circadian clock in cultivated tomato.
Jiménez-Gómez et al., Köln, Germany. In Nat Genet, Jan 2016
Allelic variation of the tomato homolog of the Arabidopsis gene EID1 is responsible for a phase delay.
The complete mitochondrial genome of the striped-tailed rat-snake, Orthriophis taeniurus (Reptilia, Serpentes, Colubridae).
Wu et al., Wuhu, China. In Mitochondrial Dna, Jan 2016
The genome is 17,183 bp in size, containing 2 ribosomal RNA (rRNA) genes, 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, and 2 control regions (CRI and CRII).
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.
Kaelin et al., Xiamen, China. In Proc Natl Acad Sci U S A, Jan 2016
EP300-interacting inhibitor of differentiation 1 (EID1) belongs to a protein family implicated in the control of transcription, differentiation, DNA repair, and chromosomal maintenance.
Protein Palmitoylation Regulates Neural Stem Cell Differentiation by Modulation of EID1 Activity.
Hao et al., Jinan, China. In Mol Neurobiol, Nov 2015
Moreover, the results show that palmitoylation modified E1A-like inhibitor of differentiation one (EID1) and this modification regulated EID1 degradation and CREB-binding protein (CBP)/p300 histone acetyltransferase activity at the switch between self-renewal and differentiation of NSCs.
FBXO21 mediates the ubiquitylation and proteasomal degradation of EID1.
Nakayama et al., Fukuoka, Japan. In Genes Cells, Aug 2015
We have now applied this approach to an uncharacterized human F-box protein, FBXO21, which serves as the substrate-recognition subunit of a SKP1-CUL1-F-box protein (SCF)-type E3, thereby identifying EID1 (EP300-interacting inhibitor of differentiation 1) as a candidate substrate.
Sequencing and analysis of the complete mitochondrial genome of Elaphe anomala (Squamata Colubridae).
Zhao et al., Harbin, China. In Mitochondrial Dna, Jul 2015
It is a circular molecule of 17,164 bp in length and contains 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, 2 ribosomal RNA (rRNA) genes and 2 control regions (CRI and CRII).
The complete mitochondrial genome of the Amur rat-snake Elaphe schrenckii (Squamata: Colubridae).
Zhao et al., Harbin, China. In Mitochondrial Dna, Jun 2015
It is a circular molecule of 17,165 bp in size and consists of 13 protein-coding genes, 22 transfer RNA (tRNA) genes, 2 ribosomal RNA (rRNA) genes and 2 control regions (CRI and CRII).
E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network.
Wang et al., Salt Lake City, United States. In Hepatology, 2014
This study unraveled a regulatory cascade involving E2F1, early growth response-1 (Egr-1), nuclear receptor small heterodimer partner (SHP, NR0B2), and EIA-like inhibitor of differentiation 1 (EID1) in cholestatic liver fibrosis.
Sulfated polysaccharides isolated from the green seaweed Caulerpa racemosa plays antinociceptive and anti-inflammatory activities in a way dependent on HO-1 pathway activation.
Benevides et al., Fortaleza, Brazil. In Inflamm Res, 2014
In this study, we investigated the potential antinociceptive activity of a sulfated polysaccharide obtained from the green seaweed Caulerpa racemosa (CrII) and the involvement of the hemoxigenase-1 (HO-1) pathway in its anti-inflammatory effect.
Structural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures.
Hart et al., Monterotondo, Italy. In J Biol Chem, 2014
Here we applied ESPRIT (expression of soluble proteins by random incremental truncation), an in vitro evolution-like approach, to identify high yielding soluble fragments encompassing conserved regions I and II (CRI and CRII) at the C-terminal region of murine Rif1.
Pcid2 inactivates developmental genes in human and mouse embryonic stem cells to sustain their pluripotency by modulation of EID1 stability.
Fan et al., Beijing, China. In Stem Cells, 2014
Pcid2 associates with EID1 and is present in the CBP/p300-EID1 complex in the ESCs.
Structural insights into gene repression by the orphan nuclear receptor SHP.
Xu et al., Grand Rapids, United States. In Proc Natl Acad Sci U S A, 2014
Although the precise mechanism whereby SHP represses transcription is not known, E1A-like inhibitor of differentiation (EID1) was isolated as a SHP-interacting protein and implicated in SHP repression.
Evolutionary conservation of an atypical glucocorticoid-responsive element in the human tyrosine hydroxylase gene.
Strong et al., San Antonio, United States. In J Neurochem, 2013
We cloned this hTH-CRII region upstream of minimal basal hTH promoter in luciferase (Luc) reporter vector, and tested glucocorticoid responsiveness in human cell lines.
Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease.
Liu et al., Grand Forks, United States. In Neurobiol Dis, 2012
This study demonstrated that overexpression of EID1 reduced hippocampal long-term potentiation and impaired spatial learning and memory function in the transgenic mice
Identification and characterization of Cri1, a locus controlling mortality during Citrobacter rodentium infection in mice.
Gruenheid et al., Montréal, Canada. In Genes Immun, 2011
Cri1 does not control C. rodentium colonic hyperplasia
The Cri1 locus is the common genetic cause of susceptibility to Citrobacter rodentium infection in C3H and FVB mouse strains.
Gruenheid et al., Montréal, Canada. In Gut Microbes, 2011
This study supports Cri1 as the major locus controlling susceptibility following murine infection with C. rodentium, and suggests a cause of mortality common to the susceptible C3, C3Ou and FVB strains of mice.
MicroRNA hsa-miR-138 inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells through adenovirus EID-1.
Zhao et al., Beijing, China. In Stem Cells Dev, 2011
miR-138 inhibited adipogenesis through targeting the nuclear receptor coregulator EID-1
E6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells.
Psyrri et al., New Haven, United States. In J Natl Cancer Inst, 2009
Repression of E6 and E7 oncogenes results in restoration of pRb suppressor pathways and induced apoptosis in HPV16-positive oropharyngeal squamous cell cancer cell lines.
RB, the conductor that orchestrates life, death and differentiation.
Chen et al., Irvine, United States. In Oncogene, 2006
In this review, we unravel the novel role of an equally important aspect of RB in downregulating the differentiation inhibitor EID-1 during cellular differentiation by teasing apart the signal, which elicit differentiation and limit cell cycle progression, since the molecular mechanisms relating to RB activation of differentiation is much less understood.
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