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Ets homologous factor

This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be involved in epithelial differentiation and carcinogenesis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] (from NCBI)
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Top mentioned proteins: CAN, BIRC5, ACID, Elf5, POLYMERASE
Papers on EHF
A 6 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis B.
Lu et al., Shanghai, China. In Front Biosci, Dec 2015
Secondly a signature consisting of 6 PGs (CD24, CXCL6, EHF, ITGBL1, LUM and SOX9) most predictive for cirrhosis risk in CHB patients was developed in the selection set (n=40) by use of PAM and PCR approach.
Effects of cow milk versus extensive protein hydrolysate formulas on infant cognitive development.
Papas et al., Philadelphia, United States. In Amino Acids, Nov 2015
To examine development of infants fed formulas differing in free amino acid content, we randomized 0.5-month-old infants (n = 79) to either a control group who fed only cow milk formula (CMF) during the first 8 months (CMF8), or to one of two experimental groups: one experimental group fed extensively protein hydrolyzed formula (EHF) for 1-3 months during first 4.5 months (EHF1-3) of life, and the other fed EHF for 8 months (EHF8).
The Transcription Factor Ehf Is Involved in TGF-β-Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells.
Shimizu et al., Tokyo, Japan. In J Immunol, Nov 2015
In this study, we found that the expression of Ets homologous factor (Ehf), a member of the Ets family transcriptional factors, is upregulated by TGF-β/Smad signaling in mouse bone marrow-derived mast cells (BMMCs).
Exploring the associations of host genes for viral infection revealed by genome-wide RNAi and virus-host protein interactions.
Bo et al., Beijing, China. In Mol Biosyst, Sep 2015
We also identified BRCA1 and TP53 (or SMAD3 and PIK3R1) being the most extensive VTP-interacting EHFs (or EHF-interacting VTPs) for HIV-1 and IAV, which hold great potential in deciphering specific infection features and discovery of host directed antivirals.
Knockdown of EHF inhibited the proliferation, invasion and tumorigenesis of ovarian cancer cells.
Qu et al., Shanghai, China. In Mol Carcinog, Sep 2015
ETS homologous factor (EHF), a member of E26 transformation specific (ETS) transcription factors, has been reported overexpressed in ovarian cancer.
[Ebola hemorrhagic fever: Properties of the pathogen and development of vaccines and chemotherapeutic agents].
Ignatjev et al., Saint Petersburg, Russia. In Mol Biol (mosk), Jul 2015
Ebola hemorrhagic fever (EHF) epidemic currently ongoing in West Africa is not the first among numerous epidemics in the continent.
Acute heat stress induces differential gene expressions in the testes of a broiler-type strain of Taiwan country chickens.
Huang et al., T'ai-chung-shih, Taiwan. In Plos One, 2014
The mRNA expressions of upregulated genes, including HSP25, HSP90AA1, HSPA2, and LPAR2, and of downregulated genes, including CDH5, CTNNA3, EHF, CIRBP, SLA, and NTF3, were confirmed through quantitative real-time polymerase chain reaction (qRT-PCR).
Transcriptome analysis of complex I-deficient patients reveals distinct expression programs for subunits and assembly factors of the oxidative phosphorylation system.
Vogel et al., Nijmegen, Netherlands. In Bmc Genomics, 2014
Analysis of evolutionarily conserved transcription factor binding sites in the promoters of these genes revealed almost all known OXPHOS regulators (including GABP, NRF1/2, SP1, YY1, E-box factors) and a set of novel candidates (ELK1, KLF7, SP4, EHF, ZNF143, and TEL2).
Gurko et al., In Adv Gerontol, 2014
The applying of millimeter-wave electromagnetic emission (EHF-therapy) is an effective method for various age-related pathologies treatment, among other cardio-vascular diseases.
Predictive and comparative analysis of Ebolavirus proteins.
Grishin et al., Dallas, United States. In Cell Cycle, 2014
Ebolavirus is the pathogen for Ebola Hemorrhagic Fever (EHF).
[Molecular mechanisms of combined extremely radiofrequency and infrared therapy in various age patients with chronic parodontitis].
D'iakonov et al., In Adv Gerontol, 2013
The influence of extreme radiofrequency millimeter microwave (EHF) and infrared (IR) electromagnetic emanation on the molecular markers of cell renovation (Ki67, p53) and proinflammatory cytokine TNF-α expression in the buccal cells of various age patients with chronic parodontitis was investigated.
Pharmacotherapy of Ebola hemorrhagic fever: a brief review of current status and future perspectives.
Gawlik et al., Kraków, Poland. In Folia Med Cracov, 2013
Currently, there is no approved therapy for Ebola hemorrhagic fever (EHF), however several advanced treatment options were tested in animal models (on non-human primates or rodents).
ESE3/EHF controls epithelial cell differentiation and its loss leads to prostate tumors with mesenchymal and stem-like features.
Carbone et al., Bellinzona, Switzerland. In Cancer Res, 2012
Low ESE3/EHF expression was also associated with increased biochemical recurrence of prostate cancer and reduced overall survival after prostatectomy
Expression of the Ets transcription factor EHF in serous ovarian carcinoma effusions is a marker of poor survival.
Davidson et al., Oslo, Norway. In Hum Pathol, 2012
EHF mRNA levels differentiate ovarian carcinoma from malignant mesothelioma. EHF may be a novel prognostic marker in ovarian carcinoma.
A member of the ETS family, EHF, and the ATPase RUVBL1 inhibit p53-mediated apoptosis.
Akiyama et al., Tokyo, Japan. In Embo Rep, 2011
These results indicate that EHF-mediated RUVBL1 expression allows colon tumour cells to avoid p53-mediated apoptosis.
Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation.
Hu et al., Toronto, Canada. In Cell Res, 2008
ESE-1 and ESE-3 play an important role in airway inflammation.
Reduced expression and tumor suppressor function of the ETS transcription factor ESE-3 in prostate cancer.
Carbone et al., Bellinzona, Switzerland. In Oncogene, 2008
Implicated as a candidate tumor suppressor in prostate cancer; decreased expression may result in loss of important regulatory mechanisms in prostate epithelial cells.
Ebola virus: immune mechanisms of protection and vaccine development.
Casillas et al., Los Angeles, United States. In Biol Res Nurs, 2003
Ebola hemorrhagic fever (EHF) is a syndrome that can rapidly lead to death within days of symptom onset.
[Effects of extremely high-frequency electromagnetic radiation on the immune system and systemic regulation of homeostasis].
Chemeris et al., Moscow, Russia. In Radiats Biol Radioecol, 2002
Low-intensity of electromagnetic radiation of extremely high frequencies (EHF EMR) is effectively used in medical practice for diagnostics, prevention and treatment of a broad spectrum of diseases of different etiology.
[Effectiveness of ulcer treatment with electromagnetic radiation of extremely high frequency (EHF therapy) and some mechanism of its therapeutic action].
Teliaper et al., In Klin Med (mosk), 2001
A clinical response to and some mechanisms of therapeutic action of extremely high frequency (EHF) therapy were studied in 132 patients with exacerbation of duodenal ulcer vs routine pharmacological treatment.
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