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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Early B cell factor 2

EBF2, early B-cell factor 2, Oe3, COE2
The protein encoded by this gene belongs to the COE (Collier/Olf/EBF) family of non-basic, helix-loop-helix transcription factors that have a well conserved DNA binding domain. The COE family proteins play an important role in variety of developmental processes. Studies in mouse suggest that this gene may be involved in the differentiation of osteoblasts. [provided by RefSeq, Oct 2011] (from NCBI)
Top mentioned proteins: EBF, CAN, ACID, Ubiquitin, V1a
Papers using EBF2 antibodies
Distinct ontogenic and regional expressions of newly identified Cajal–Retzius cell-specific genes during neocorticogenesis
Portera-Cailliau Carlos et al., In Frontiers in Neuroanatomy, 2003
... Ebf2-GFP BAC transgenic mice were engineered through ...
Papers on EBF2
Seedlings Transduce the Depth and Mechanical Pressure of Covering Soil Using COP1 and Ethylene to Regulate EBF1/EBF2 for Soil Emergence.
Zhong et al., Beijing, China. In Curr Biol, Jan 2016
We show that COP1 directly targets the F box proteins EBF1 and EBF2 for ubiquitination and degradation, thus stabilizing EIN3.
The gene encoding the mouse contactin-1 axonal glycoprotein is regulated by the collier/Olf1/EBF family early B-Cell factor 2 transcription factor.
Gennarini et al., Bari, Italy. In Dev Neurobiol, Dec 2015
Likewise, null mutant mice for the Collier/Olf1/Early B-cell family transcription factor EBF2, in which Purkinje neuron development is primarily affected, exhibit abnormalities in cerebellar corticogenesis.
Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse.
Zhou et al., Shanghai, China. In Dev Neurobiol, Nov 2015
Moreover, transcription factor early B-cell factor 2 (Ebf2) was transiently expressed in a subset of DA neurons in embryonic ventral mesencephalon.
Gene-Specific Translation Regulation Mediated by the Hormone-Signaling Molecule EIN2.
Alonso et al., Raleigh, United States. In Cell, Nov 2015
Characterization of one of the targets of this translation regulatory machinery, the ethylene signaling component EBF2, indicates that the signaling molecule EIN2 and the nonsense-mediated decay proteins UPFs play a central role in this ethylene-induced translational response.
EIN2-Directed Translational Regulation of Ethylene Signaling in Arabidopsis.
Guo et al., Beijing, China. In Cell, Nov 2015
In this study, we report another mechanism of EIN2-mediated ethylene signaling, whereby EIN2 imposes the translational repression of EBF1 and EBF2 mRNA.
Diet-Induced Podocyte Dysfunction in Drosophila and Mammals.
Cagan et al., New York City, United States. In Cell Rep, Aug 2015
We demonstrate upregulation of the Knot ortholog EBF2 in glomeruli of human diabetic nephropathy patients and a mouse ob/ob diabetes model.
Shades of brown: a model for thermogenic fat.
Sul et al., Berkeley, United States. In Front Endocrinol (lausanne), 2014
Here, we highlight recent advances in the understanding of brown and beige/brite adipocytes as well as transcriptional regulation for development and function of murine brown and beige/brite adipocytes focusing on EBF2, IRF4, and ZFP516, in addition to PRDM16 as a coregulator.
A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia.
Avins et al., Oakland, United States. In Nat Commun, 2014
We identify four novel inguinal hernia susceptibility loci in the regions of EFEMP1, WT1, EBF2 and ADAMTS6.
Only a minority of broad-range detoxification genes respond to a variety of phytotoxins in generalist Bemisia tabaci species.
Morin et al., Jerusalem, Israel. In Sci Rep, 2014
Three genes, COE2, CYP6-like 5 and BtGST2, responded to more than one compound and were highly transcribed in the insect gut.
EBF2 determines and maintains brown adipocyte identity.
Seale et al., Philadelphia, United States. In Cell Metab, 2013
Here, we show that early B cell factor-2 (Ebf2) regulates Pparγ binding activity to determine brown versus white adipocyte identity.
Transcriptional regulation of the hypocretin/orexin gene.
Tanaka, Tokyo, Japan. In Vitam Horm, 2011
In addition, some transcription factors, such as forkhead box A2; nuclear receptor subfamily 6, group A, member 1; and early B-cell factor 2, were determined to be regulators of the preprohypocretin gene.
Paradigms and paradox in the ethylene signaling pathway and interaction network.
Guo et al., Beijing, China. In Mol Plant, 2011
With the recent demonstration of the regulation of the protein stability of numerous key signaling components including EIN3, EIL1, EIN2, ETR2, EBF1/EBF2, and ETP1/ETP2, we highlight proteasome-dependent protein degradation as an essential regulatory mechanism that is widely adopted in the ethylene signaling pathway.
Aspects of the narcolepsy-cataplexy syndrome in O/E3-null mutant mice.
Vidaltamayo et al., Mexico. In Neuroscience, 2011
This study demonistrated that reveal that O/E3-null mouse is a different model of narcolepsy where the orexinergic circuitry is distorted. Evidence proves that many neuronal subpopulations are altered in O/E3-null mice.
Both Schwann cell and axonal defects cause motor peripheral neuropathy in Ebf2-/- mice.
Corradi et al., Genova, Italy. In Neurobiol Dis, 2011
Ebf2 is implicated in peripheral nerve development as a potential candidate gene for peripheral nerve disorders.
Ebf2 marks early cortical neurogenesis and regulates the generation of cajal-retzius neurons in the developing cerebral cortex.
Shen et al., Kao-hsiung, Taiwan. In Dev Neurosci, 2010
Ebf2 is important for early cortical neurogenesis and regulates the generation of Cajal-Retzius neurons in the developing cerebral cortex.
Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner.
Grosschedl et al., Freiburg, Germany. In Cell Stem Cell, 2010
Ebf2 acts as a transcriptional determinant of an osteoblastic niche that regulates the maintenance of hematopoietic progenitors, in part by modulating Wnt signaling
Profiling of chemonaive osteosarcoma and paired-normal cells identifies EBF2 as a mediator of osteoprotegerin inhibition to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
Lecanda et al., Pamplona, Spain. In Clin Cancer Res, 2009
EBF2 as a mediator of osteoprotegerin inhibition to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
Genetic basis of ethylene perception and signal transduction in Arabidopsis.
Guo et al., Beijing, China. In J Integr Plant Biol, 2008
In the absence of ethylene signal, EIN3 protein is degraded by an SCF complex containing one of the two F-box proteins EBF1/EBF2 in a 26S proteasome-dependent manner.
Plant responses to ethylene gas are mediated by SCF(EBF1/EBF2)-dependent proteolysis of EIN3 transcription factor.
Ecker et al., Los Angeles, United States. In Cell, 2004
In the absence of ethylene, EIN3 is quickly degraded through a ubiquitin/proteasome pathway mediated by two F box proteins, EBF1 and EBF2.
EIN3-dependent regulation of plant ethylene hormone signaling by two arabidopsis F box proteins: EBF1 and EBF2.
Genschik et al., Strasbourg, France. In Cell, 2004
Here, we identify two Arabidopsis F box proteins called EBF1 and EBF2 that interact physically with EIN3/EIL transcription factors.
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