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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Nuclear protein, ataxia-telangiectasia locus

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Top mentioned proteins: Histone, PCNA, CDK2, CAN, ACID
Papers using E14 antibodies
Expression and function of cannabinoid receptors CB1 and CB2 and their cognate cannabinoid ligands in murine embryonic stem cells.
Najbauer Joseph, In PLoS ONE, 2006
... E14 differentiation to epithelial cells in 3D cultureGrowth Factor Reduced Matrigel was purchased from BD Biosciences (354230) ...
A novel splicing regulator shares a nuclear import pathway with SR proteins.
Schmidt Edward E., In PLoS ONE, 2002
... The E14 ES cell was injected into mouse strain C57BL/6 blastocysts to generate chimeric mice by Transgenic Core Facility at the ...
Experimental modeling of spinal cord injury: characterization of a force-defined injury device
Okano Hideyuki et al., In Molecular Brain, 2002
... (C-E) At E14.5 d, reporter gene expression patterns were quite similar between the transgenic ...
MAP kinases, phosphatidylinositol 3-kinase, and p70 S6 kinase mediate the mitogenic response of human endothelial cells to vascular endothelial growth factor
Christofori Gerhard et al., In The Journal of Cell Biology, 1998
... The amplification products were used to screen an e14.5 mouse embryo cDNA library in λGT11 (CLONTECH Laboratories, Inc.) following the ...
Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development
Schubert Michael, In PLoS ONE, 1996
... To generate the mESC-derived line, the linearized BRE-gal construct was electroporated into 129P2/Ola derived E14 embryonic stem (ES) cells (UCI Transgenic Mouse Facility) ...
Papers on E14
Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription.
Luo et al., Hangzhou, China. In J Biol Chem, Jan 2016
As a direct substrate of Cyclin E/CDK2, nuclear protein ataxia-telangiectasia (NPAT) is a crucial factor in regulating histone transcription and cell cycle progression.
FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors.
Schümperli et al., Bern, Switzerland. In Nucleic Acids Res, Dec 2015
Interestingly, FUS antibodies also co-immunoprecipitate histone transcriptional activator NPAT and transcriptional repressor hnRNP UL1 in different phases of the cell cycle.
A conserved interaction that is essential for the biogenesis of histone locus bodies.
Dominski et al., Chapel Hill, United States. In J Biol Chem, 2015
Nuclear protein, ataxia-telangiectasia locus (NPAT) and FLICE-associated huge protein (FLASH) are two major components of discrete nuclear structures called histone locus bodies (HLBs).
Cyclin E2 is the predominant E-cyclin associated with NPAT in breast cancer cells.
Caldon et al., Sydney, Australia. In Cell Div, 2014
However cyclin E2 uniquely co-localises with NPAT, the main activator of cell-cycle regulated histone transcription.
High-resolution molecular validation of self-renewal and spontaneous differentiation in clinical-grade adipose-tissue derived human mesenchymal stem cells.
van Wijnen et al., Rochester, United States. In J Cell Biochem, 2014
For example, cell cycle-related biomarkers (e.g., cyclins E2 and B2, transcription factor E2F1) and histone-related genes (e.g., H4, HINFP, NPAT) are elevated in proliferating AMSCs, while ECM genes are strongly upregulated (>10-fold) in quiescent AMSCs.
You cannot tell a book by looking at the cover: Cryptic complexity in bacterial evolution.
Austin et al., Urbana, United States. In Biomicrofluidics, 2014
Further the GASP strain evolves a prophage e14 excision which completely inhibits biofilm formation in the mutant strain, revealing the hidden complexity of E. coli evolution to antibiotics as a function of selection pressure.
Embryonic development of circadian oscillations in the mouse hypothalamus.
Davis et al., Boston, United States. In J Biol Rhythms, 2014
SCN explants obtained on e14 did not initially express oscillations but developed them in vitro over 4 to 6 d.
Dynamic changes in DNA modification states during late gestation male germ line development in the rat.
Drake et al., Edinburgh, United Kingdom. In Epigenetics Chromatin, 2013
RESULTS: Using immunofluorescence, we demonstrate that 5mC is re-established between e18.5 and e21.5 in the rat, subsequent to loss of 5hmC, 5fC and 5caC, which are present in germ cells between e14.5 and e16.5.
[Atypical BCR-ABL transcripts in patients with chronic myeloid leukemia--the scheme for the diagnosis and monitoring of minimal residual disease].
Skotnicki et al., In Przegl Lek, 2013
More than 95% of patients with detected translocation t(9;22), is characterized by the fusion between exons e13 or e14 of BCR gene, which are located in major breakpoint cluster region (M-bcr) and exon a2 of ABL gene.
Genetic variants of NPAT-ATM and AURKA are associated with an early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy.
Imai et al., Chiba, Japan. In Int J Radiat Oncol Biol Phys, 2011
Genetic variants of NPAT-ATM and AURKA are associated with an individual early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy
Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma.
Aaltonen et al., Helsinki, Finland. In Blood, 2011
NPAT is thus far the first gene implicated in nodular lymphocyte predominant Hodgkin lymphoma predisposition.
Induced G1 cell-cycle arrest controls replication-dependent histone mRNA 3' end processing through p21, NPAT and CDK9.
Johnsen et al., Göttingen, Germany. In Oncogene, 2010
NPAT is essential for histone mRNA 3' end processing and recruits CDK9 to replication-dependent histone genes.
Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells.
Stein et al., Worcester, United States. In J Cell Physiol, 2010
Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells.
Technical aspects and clinical applications of measuring BCR-ABL1 transcripts number in chronic myeloid leukemia.
Marin et al., London, United Kingdom. In Am J Hematol, 2009
The breakpoint in the BCR gene occurs commonly downstream of exons e13 or e14 (M-BCR) and less frequently downstream of exons e1 and e2 (m-BCR).
The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles.
Stein et al., Worcester, United States. In Proc Natl Acad Sci U S A, 2009
Data indicate that the CDK2/cyclin E/p220(NPAT)/HINFP/histone gene signaling pathway at the G1/S phase transition is an essential, nonredundant cell cycle regulatory mechanism that is established early in embryogenesis.
Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells.
Stein et al., Worcester, United States. In J Cell Physiol, 2007
In somatic cells, histone H4 gene expression is controlled by CDK2 phosphorylation of p220(NPAT) and localization of HiNF-P/p220(NPAT) complexes with histone genes at Cajal body related subnuclear foci.
An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.
Braastad et al., Worcester, United States. In J Cell Physiol, 2006
Histone nuclear factor P (HiNF-P), the principal factor mediating H4 histone gene transcription, is the final link in the signaling cascade that is initiated with growth factor dependent induction of cyclin E/CDK2 kinase activity at the R-point and culminates in the NPAT-mediated activation of histone H4 genes through HiNF-P at the G1/S phase cell-cycle transition.
Coordination of DNA synthesis and histone gene expression during normal cell cycle progression and after DNA damage.
Zhao, Rochester, United States. In Cell Cycle, 2004
Regulation of the cyclin E-Cdk2 substrate NPAT, which is essential for both histone gene expression and S phase entry, provides a mechanism coordinating histone and DNA synthesis in mammalian cells.
A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapy.
Almasan et al., Cleveland, United States. In Curr Cancer Drug Targets, 2004
Rb, as well as Cdc6, NPAT, and nucleophosmin, critical components of cell proliferation and DNA replication, respectively, are targets of Cyclin E/Cdk2 phosphorylation.
S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.
Luo et al., New York City, United States. In Cell, 2003
OCA-S, the multicomponent Oct-1 coactivator, intercts with NPAT.
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