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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

DAZ interacting protein 1

Dzip1, DAZ-interacting protein, daz-interacting protein 1, DZIP
Top mentioned proteins: Gli, SUFU, Ihh, DAZ, Shh
Papers on Dzip1
Epigenetic regulation of KLHL34 predictive of pathologic response to preoperative chemoradiation therapy in rectal cancer patients.
Kim et al., Seoul, South Korea. In Int J Radiat Oncol Biol Phys, Apr 2015
RESULTS: Genome-wide screening identified 7 hypermethylated CpG sites (DZIP1 cg24107021, DZIP1 cg26886381, ZEB1 cg04430381, DKK3 cg041006961, STL cg00991794, KLHL34 cg01828474, and ARHGAP6 cg07828380) associated with preoperative CRT responses.
Ribonomic analysis of human DZIP1 reveals its involvement in ribonucleoprotein complexes and stress granules.
Dallagiovanna et al., Curitiba, Brazil. In Bmc Mol Biol, 2013
BACKGROUND: DZIP1 (DAZ-interacting protein 1) has been described as a component of the Hh signaling pathway with a putative regulatory role in ciliogenesis.
Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis.
Wang et al., In J Biol Chem, 2013
Here we show that the mouse DZIP1 regulates Hedgehog signaling through two mechanisms.
Development of a novel approach, the epigenome-based outlier approach, to identify tumor-suppressor genes silenced by aberrant DNA methylation.
Ushijima et al., Tokyo, Japan. In Cancer Lett, 2012
Among these, DZIP1, FBN2, HOXA5, and HOXC9 were confirmed to be methylated in primary breast cancer samples.
Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease.
Gao et al., In Sci Rep, 2011
An association between a rare, coding, non-synonymous SNP variant in the gene DZIP1 and Parkinson's disease was found, based on an analysis of the existing NGRC genome-wide association study dataset.
The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1.
Yang et al., Columbus, United States. In J Biol Chem, 2011
reversible phosphorylation of Dzip1, which is controlled by the antagonistic action of CK2 and B56-containing PP2As, has an important impact on the stability of Gli transcription factors and Hh signaling.
Hedgehog signaling via angiopoietin1 is required for developmental vascular stability.
Childs et al., Calgary, Canada. In Mech Dev, 2010
The zebrafish iguana (igu) genetic mutant has a mutation in the daz-interacting protein 1 (dzip1), a member of the hedgehog signaling pathway.
The iguana/DZIP1 protein is a novel component of the ciliogenic pathway essential for axonemal biogenesis.
Roy et al., Singapore, Singapore. In Dev Dyn, 2010
critical component of ciliogenesis
The Zn finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis.
Reddien et al., Cambridge, United States. In Dev Biol, 2010
Results indicate that a critical and broadly conserved function for Iguana is in ciliogenesis and that this function has come to be required for Hedgehog signaling in vertebrates
Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish.
Ingham et al., Sheffield, United Kingdom. In Bmc Biol, 2009
Moreover, we show that the Igu/DZIP1protein, previously implicated in the modulation of Gli activity in zebrafish, also localizes to the primary cilium and is required for its proper formation.
Expression of zebrafish hip: response to Hedgehog signalling, comparison with ptc1 expression, and possible role in otic patterning.
Whitfield et al., Sheffield, United Kingdom. In Gene Expr Patterns, 2009
Here we show that genes coding for three inhibitors of Hh signalling, su(fu), dzip1 and hip, are expressed in and around the developing otic vesicle.
Gene expression analysis of the hedgehog signaling cascade in the chick midbrain and spinal cord.
Agarwala et al., Austin, United States. In Dev Dyn, 2007
Intriguingly, multiple HH-binding proteins (BOC, MEGALIN) and HH effectors (GLI1-3, SMO, SUFU, DZIP) are expressed in the dorsal midbrain and the midbrain-hindbrain boundary.
Hedgehog signaling pathway and gastrointestinal stem cell signaling network (review).
Katoh et al., Tokyo, Japan. In Int J Mol Med, 2006
Iguana homologs (DZIP1 and DZIP1L) and Costal-2 homologs (KIF7 and KIF27) are identified by comparative integromics.
Characterization of structure and expression of the Dzip1 gene in the rat and mouse.
Aitken et al., Newcastle, Australia. In Genomics, 2006
Dzip1S mRNA was confined to the spermatogenic lineage, specifically premeiotic spermatogonia
WNT antagonist, SFRP1, is Hedgehog signaling target.
Katoh et al., Japan. In Int J Mol Med, 2006
The Hedgehog signal is transduced to GLI family transcription factors though Patched receptor, Smoothened signal transducer, and other signaling components, such as KIF27, KIF7, STK36, SUFU, and DZIP1.
Differential susceptibility of midbrain and spinal cord patterning to floor plate defects in the talpid2 mutant.
Ragsdale et al., Austin, United States. In Dev Biol, 2006
Together with the failure of SHH misexpression to rescue the talpid2 phenotype, these results suggest that talpid2 is likely to have a tissue-autonomous, bidirectional (positive and negative) role in HH signaling that cannot be attributed to the altered expression of several newly cloned HH pathway genes (SUFU, DZIP1, DISP1, BTRC).
Hedgehog signaling pathway and gastric cancer.
Katoh et al., Japan. In Cancer Biol Ther, 2005
Human SHH, IHH, DHH (Hedgehog homologs), HHAT (Hedgehog acyltransferase), HHIP (Hedgehog-interacting protein), DISP1, DISP2, DISP3 (Dispatched homologs), PTCH1, PTCH2 (Patched homologs), SMO (Smoothened homolog), KIF27, KIF7 (Costal-2 homologs), STK36 (Fused homolog), SUFU (SuFu homolog), DZIP1 (Iguana homolog), GLI1, GLI2 and GLI3 (Cubitus interruptus homologs) are implicated in the Hedgehog signaling.
iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo.
Ingham et al., Sheffield, United Kingdom. In Genes Dev, 2004
zebrafish iguana gene product acts in the somites of the developing embryo and can shuttle between the cytoplasm and nucleus in a manner correlated with Hedgehog pathway activity.
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