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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Dual specificity phosphatase 23

DUSP23, VHZ, Dual specificity protein phosphatase 23, MOSP, VH1-like member Z, low-molecular-mass dual-specificity phosphatase 3, LDP-3, DUSP25
Top mentioned proteins: ACID, CAN, CD45, MKP-1, Pts
Papers on DUSP23
Profiling analysis of protein tyrosine phosphatases during neuronal differentiation.
Han et al., Taejŏn, South Korea. In Neurosci Lett, Jan 2016
In particular, it was found that dual-specific phosphatase23 (DUSP23) affected neuronal differentiation.
Radolf et al., Farmington, United States. In J Biol Chem, Jun 2015
We also reported that TprC contains N- and C-terminal domains (TprC(N) and TprC(C)) orthologous to regions in the major outer sheath protein (MOSP(N) and MOSP(C)) of Treponema denticola and that TprC(C) is solely responsible for β-barrel formation, trimerization, and porin function by the full-length protein.
Graft of the gelatin sponge scaffold containing genetically-modified neural stem cells promotes cell differentiation, axon regeneration, and functional recovery in rat with spinal cord transection.
Zeng et al., Guangzhou, China. In J Biomed Mater Res A, Apr 2015
Immunofluorescence staining showed the grafted NSCs could differentiate into microtubule associated protein (Map2), postsynaptic density (PSD95), and mouse oligodendrocyte special protein (MOSP) positive cells.
The degree of astrocyte activation in multiple system atrophy is inversely proportional to the distance to α-synuclein inclusions.
Pountney et al., Gold Coast, Australia. In Mol Cell Neurosci, Mar 2015
In primary cell culture studies, α-syn addition caused ERK-dependent activation of rat astrocytes and perinuclear α-syn inclusions in mature (MOSP-positive) rat oligodendrocytes.
New functional aspects of the atypical protein tyrosine phosphatase VHZ.
Hengge et al., Logan, United States. In Biochemistry, 2013
LDP3 (VHZ) is the smallest classical protein tyrosine phosphatase (PTP) known to date and was originally misclassified as an atypical dual-specificity phosphatase.
The major outer sheath protein (Msp) of Treponema denticola has a bipartite domain architecture and exists as periplasmic and outer membrane-spanning conformers.
Radolf et al., Farmington, United States. In J Bacteriol, 2013
The Conserved Domain Database (CDD) server revealed that Msp contains two conserved domains, major outer sheath protein(N) (MOSP(N)) and MOSP(C), spanning residues 77 to 286 and 332 to 543, respectively, within the N- and C-terminal regions of the protein.
Identification of potent VHZ phosphatase inhibitors with structure-based virtual screening.
Ryu et al., Seoul, South Korea. In J Biomol Screen, 2013
VH1-like phosphatase Z (VHZ) has proved to be a promising target for the development of therapeutics for the treatment of human cancers.
New aspects of the phosphatase VHZ revealed by a high-resolution structure with vanadate and substrate screening.
Johnson et al., Logan, United States. In Biochemistry, 2013
The recently discovered 150-residue human VHZ (VH1-related protein, Z member) is one of the smallest protein tyrosine phosphatases (PTPs) known and contains only the minimal structural elements common to all PTPs.
Metavanadate at the active site of the phosphatase VHZ.
Hengge et al., Logan, United States. In J Am Chem Soc, 2012
We performed a computational analysis of a 1.14 Å structure of the phosphatase VHZ in complex with an unusual metavanadate species and compared it with two classical trigonal-bipyramidal vanadate-phosphatase complexes.
Myelin oligodendrocyte-specific protein is expressed in Müller cells of myelinated vertebrate retinas.
Prada et al., Sevilla, Spain. In J Neurosci Res, 2011
By immunohistochemistry, with a monoclonal antibody against myelin oligodendrocyte-specific protein (MOSP), we show that MOSP is intensely expressed in the MC and the optic-fiber layer (OFL) in myelinated but not in unmyelinated retinas.
Dual-specificity phosphatase 23 mediates GCM1 dephosphorylation and activation.
Chen et al., Taipei, Taiwan. In Nucleic Acids Res, 2011
Here we show that the interaction of GCM1 and dual-specificity phosphatase 23 (DUSP23) is enhanced by PKA-dependent phosphorylation of GCM1 on Ser269 and Ser275.
Identification of epigenetically regulated genes that predict patient outcome in neuroblastoma.
Martinsson et al., Göteborg, Sweden. In Bmc Cancer, 2010
RESULTS: We present eight genes (KRT19, PRKCDBP, SCNN1A, POU2F2, TGFBI, COL1A2, DHRS3 and DUSP23) that are methylated in neuroblastoma, most of them not previously reported as such, some of which also distinguish between biological subsets of neuroblastoma tumors.
VHZ is a novel centrosomal phosphatase associated with cell growth and human primary cancers.
Zeng et al., Singapore, Singapore. In Mol Cancer, 2009
The upregulation of VHZ levels in primary human cancers supports the clinical relevance of this protein in cancers
Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex.
Swaminathan et al., United States. In J Biol Chem, 2008
Dual specificity protein phosphatase 23 (DUSP23) or VHZ mediates dephosphorylation of phospho-tyrosyl (pTyr) and phospho-seryl/threonyl (pSer/pThr) residues in specific proteins.
The minimal essential core of a cysteine-based protein-tyrosine phosphatase revealed by a novel 16-kDa VH1-like phosphatase, VHZ.
Mustelin et al., Los Angeles, United States. In J Biol Chem, 2004
the smallest active protein-tyrosine phosphatase yet (only 16 kDa) belongs to the group of small Vaccinia virus VH1-related dual specific phosphatases; gene is located on human chromosome 1q23.1 and consists of only two coding exons
Molecular cloning and characterization of a novel dual-specificity phosphatase 23 gene from human fetal brain.
Mao et al., Shanghai, China. In Int J Biochem Cell Biol, 2004
DUSP23 showed distinctive phosphatase activity toward p-nitrophenyl phosphate, as well as oligopeptides containing phospho-tyrosine and phospho-threonine residues. Furthermore, DUSP23 could dephosphorylate p44ERK1 but not p38 and p54SAPKbeta in vitro
Novel oligodendrocyte transmembrane signaling systems. Investigations utilizing antibodies as ligands.
Dyer, Waltham, United States. In Mol Neurobiol, 1992
Binding of specific antibodies to the oligodendrocyte membrane surface markers myelin/oligodendrocyte glycoprotein (MOG), myelin/oligodendrocyte specific protein (MOSP), galactocerebroside (GalC), and sulfatide on cultured murine oligodendrocytes results in different effects with regard to phospholipid turnover, Ca2+ influxes, and antibody:marker distribution.
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