GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Deltex homolog 3
DTX3, Deltex3
DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009] (from
NCBI)
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Top mentioned proteins:
ACID, DSP, fibrillin-1, DTX2, STEP
Papers on
DTX3
In vitro bioaccessibility of the marine biotoxin okadaic acid in shellfish.
New
Lisbon, Portugal. In Food Chem Toxicol, Feb 2016
Naturally contaminated mussels (Mytilus galloprovincialis) and donax clams (Donax sp.), collected from the Portuguese coast, containing OA and dinophysistoxin-3 (DTX3) were used in this study.
Development and Validation of a Lateral Flow Immunoassay for the Rapid Screening of Okadaic Acid and All Dinophysis Toxins from Shellfish Extracts.
New
Lansing, United States. In J Agric Food Chem, Oct 2015
DTX3 detection could be included with the addition of a hydrolysis procedure.
Distribution of DTX-3 in edible and non-edible parts of Crenomytilus grayanus from the Sea of Japan.
New
Vladivostok, Russia. In Toxicon, May 2015
Seasonal dynamics and the distribution of dinophysistoxin-3 (DTX-3) in organs of mussel Crenomytilus grayanus, collected in 2013 in Peter the Great Bay, Sea of Japan, were determined.
Assimilation, Accumulation, and Metabolism of Dinophysistoxins (DTXs) and Pectenotoxins (PTXs) in the Several Tissues of Japanese Scallop Patinopecten yessoensis.
Yokohama, Japan. In Toxins (basel), 2014
DTX1 and PTX2 were the dominant toxins in the D. fortii cells fed to the scallops, whereas the dominant toxins detected in the digestive gland of scallops were PTX6 and esterified acyl-O-DTX1 (DTX3).
An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.
Impact
Chapel Hill, United States. In Nat Genet, 2014
The genes identified include eight that are essential for cell proliferation (FGD5, METTL6, CPT1A, DTX3, MRPS23, EIF2S2, EIF6 and SLC2A10) and are uniquely amplified in patients with highly proliferative luminal breast tumors, a clinical subset of patients for which few therapeutic options are effective.
In vitro acylation of okadaic acid in the presence of various bivalves' extracts.
Sendai, Japan. In Mar Drugs, 2013
In the bivalves exposed to the toxic bloom of the dinoflagellate, dinophysistoxin 3 (DTX3), the 7-OH acylated form of either okadaic acid (OA) or DTX1, is produced.
Isolation and characterization of an enzyme from the Greenshell™ mussel Perna canaliculus that hydrolyses pectenotoxins and esters of okadaic acid.
New Zealand. In Toxicon, 2012
The enzyme also hydrolysed short and medium chain length (C2-C10) 4-nitrophenyl-esters, okadaic acid C8-C10 diol esters and DTX1 7-O-palmitoyl ester (DTX3).
Lipophilic toxin profiles detected in farmed and benthic mussels populations from the most relevant production zones in Southern Chile.
Santiago, Chile. In Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2011
After the analysis, four toxins were found: DTX-1, DTX-3, YTX and PTX.
First evidence of Okadaic acid acyl-derivative and Dinophysistoxin-3 in mussel samples collected in Chiloe Island, Southern Chile.
Santiago, Chile. In J Toxicol Sci, 2010
The amount of Dinophysistoxin-3 (DTX-3) measured in the shellfish extracts were in average above the international safe limits for DSP content in the shellfish extracts analyzed.
Development and single-laboratory validation of a pseudofunctional biosensor immunoassay for the detection of the okadaic acid group of toxins.
Ireland. In Anal Chem, 2010
The assay was also validated to confirm the ability to accurately codetect and quantify dinophysistoxin-1 (DTX-1), DTX-2, and DTX-3 from shellfish matrix.
Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer.
Galway, Ireland. In Bmc Mol Biol, 2009
RESULTS: The expression of thirteen candidate EC genes: B2M, HPRT, GAPDH, ACTB, PPIA, HCRT, SLC25A23, DTX3, APOC4, RTDR1, KRTAP12-3, CHRNB4 and MRPL19 were analysed in a cohort of 64 colorectal tumours and tumour associated normal specimens.
Enzymatic hydrolysis of esterified diarrhetic shellfish poisoning toxins and pectenotoxins.
Halifax, Canada. In Anal Bioanal Chem, 2007
Porcine pancreatic lipase induced complete conversion of DTX3 to OA and DTXs within one hour for reference solutions.
Report on the first detection of pectenotoxin-2, spirolide-a and their derivatives in French shellfish.
Nantes, France. In Mar Drugs, 2006
In order to investigate the presence of acyl-OAs and/or acyl-DTX-1,-2 (DTX-3), alkaline hydrolysis was performed on all samples, and LC/MS analyses were carried out on the samples before and after hydrolysis.
Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains.
GeneRIF
Paris, France. In Embo Rep, 2006
We show here that both molecules (Deltex (DTX) and AIP4) interact and partially colocalize to endocytic vesicles, and that AIP4 targets DTX for lysosomal degradation.
Metabolic transformation of dinophysistoxin-3 into dinophysistoxin-1 causes human intoxication by consumption of O-acyl-derivatives dinophysistoxins contaminated shellfish.
Santiago, Chile. In J Toxicol Sci, 2005
This paper describes for the first time a massive intoxication episode due to consumption of shellfish contaminated with 7-O-acyl-derivative dinophysistoxin-1, named Dinophysistoxin-3 (DTX-3).
The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity.
GeneRIF
Boston, United States. In J Biol Chem, 2003
It is reported that BBAP and the human family of DTX proteins (DTX1, DTX2, and DTX3) function as E3 ligases based on their capacity for self-ubiquitination.
Suppression of differentiation and proliferation of early chondrogenic cells by Notch.
Noda, Japan. In J Bone Miner Metab, 2002
Notch1, Delta-like (Dll)1, Deltex2, and Deltex3 were coexpressed after 6-day insulin treatment.
