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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Pinin, desmosome associated protein

expression is suppressed in cells transformed by v-src and other oncogenes, however expression is not suppressed in HPV type 16 E6E7 or polyomavirus large T transformed cells [RGD, Jan 2010] (from NCBI)
Top mentioned proteins: CAN, HAD, DRB1, V1a, ACID
Papers on DRS
Lopinavir Resistance Classification with Imbalanced Data Using Probabilistic Neural Networks.
Nobre et al., Rio de Janeiro, Brazil. In J Med Syst, Mar 2016
The aim of this study was to develop classifiers for predicting resistance to the HIV protease inhibitor lopinavir using a probabilistic neural network (PNN).
Dopamine and T cells: dopamine receptors and potent effects on T cells, dopamine production in T cells, and abnormalities in the dopaminergic system in T cells in autoimmune, neurological and psychiatric diseases.
Levite, Jerusalem, Israel. In Acta Physiol (oxf), Jan 2016
The review covers the following findings: (i) T cells express functional dopamine receptors (DRs) D1R-D5R, but their level and function are dynamic and context-sensitive, (ii) DR membranal protein levels do not necessarily correlate with DR mRNA levels, (iii) different T cell types/subtypes have different DR levels and composition and different responses to dopamine, (iv) autoimmune and pro-inflammatory T cells and T cell leukaemia/lymphoma also express functional DRs, (v) dopamine (~10(-8) M) activates resting/naive Teffs (CD8(+) >>>CD4(+) ), (vi) dopamine affects Th1/Th2/Th17 differentiation, (vii) dopamine inhibits already activated Teffs (i.e.
Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells.
Lee et al., Baltimore, United States. In Hepatology, Jan 2016
aHSCs are associated with elevated expression of death receptors (DRs) and become sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell death.
Urea hydration from dielectric relaxation spectroscopy: old findings confirmed, new insights gained.
Buchner et al., Kazan', Russia. In Phys Chem Chem Phys, Jan 2016
UNASSIGNED: We report results on urea hydration obtained by dielectric relaxation spectroscopy (DRS) in a broad range of concentrations and temperatures.
The hyaluronan and proteoglycan link proteins: Organizers of the brain extracellular matrix and key molecules for neuronal function and plasticity.
Carulli et al., Okayama, Japan. In Exp Neurol, Dec 2015
This review summarizes the recent advances in understanding the role of Haplns in the formation and control of two distinct types of perineuronal matrices, one for "classical" PNN and the other for the specialized extracellular matrix (ECM) at the node of Ranvier in the central nervous system (CNS).
A promising "TRAIL" of tanshinones for cancer therapy.
Chang et al., Taiwan. In Biomedicine (taipei), Nov 2015
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) elicits apoptosis by engaging its cognate death receptors (DRs-namely, DR4 and DR5.
Hydrogenation and dehydrogenation iron pincer catalysts capable of metal-ligand cooperation by aromatization/dearomatization.
Milstein et al., Israel. In Acc Chem Res, Aug 2015
More specifically, we have studied complexes of various transition metals (Ru, Fe, Co, Rh, Ir, Ni, Pd, Pt, and Re) bearing pyridine- and bipyridine-based PNP and PNN pincer ligands, which have slightly acidic methylene protons.
Spatial dynamics of TRAIL death receptors in cancer cells.
Zhang et al., Silver Spring, United States. In Drug Resist Updat, Mar 2015
Currently, multiple clinical trials are underway to evaluate the antitumor activity of recombinant human TRAIL (rhTRAIL) and agonistic antibodies that target death receptors (DRs) 4 or 5.
Development and Structural Variety of the Chondroitin Sulfate Proteoglycans-Contained Extracellular Matrix in the Mouse Brain.
Nishi et al., Kashihara, Japan. In Neural Plast, 2014
Although previous studies have examined the starting period of PNN formation, focusing on primary sensory cortices, there are no systematic studies at the whole brain level.
Modeling of Dopamine D2 Receptor - Overview of 35-Year Evolution.
Kostic-Rajacic et al., Mainz, Germany. In Curr Med Chem, 2014
Methods of medicinal chemistry, molecular and structural biology as well as computational chemistry were used in the studies of DA receptors (DRs).
The extracellular matrix in plasticity and regeneration after CNS injury and neurodegenerative disease.
Fawcett, Cambridge, United Kingdom. In Prog Brain Res, 2014
Knockout of the PNN-organizing protein Crtl1 link protein attenuates PNNs and leads to continued plasticity into adulthood, demonstrating that the CSPGs in PNNs are the key components in the control of plasticity.
Suppression of viral replication by drs tumor suppressor via mTOR dependent pathway.
Inoue et al., Ōtsu, Japan. In Cancer Lett, 2012
Drs suppresses viral replication via mTOR-dependent pathway.
Functional regeneration of respiratory pathways after spinal cord injury.
Silver et al., Cleveland, United States. In Nature, 2011
Here we show that, after cervical spinal cord injury, the expression of chondroitin sulphate proteoglycans (CSPGs) associated with the perineuronal net (PNN) is upregulated around the phrenic motor neurons.
Pnn and SR family proteins are differentially expressed in mouse central nervous system.
Ouyang et al., Shancheng, China. In Histochem Cell Biol, 2011
The results suggest that astrocytes are unique among cell types of neuroblast origin in terms of expression Pinin protein.
Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis.
Sugrue et al., Gainesville, United States. In Dev Biol, 2010
Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis
Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study.
Shak et al., London, United Kingdom. In J Clin Oncol, 2010
RESULTS Reportable scores were available from 1,231 evaluable patients (N0, n = 872; N+, n = 306; and node status unknown, n = 53); 72, 74, and six DRs occurred in N0, N+, and node status unknown patients, respectively.
Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton.
Adham et al., Göttingen, Germany. In Bmc Cell Biol, 2009
PELO is subcellularly localized at the actin cytoskeleton, interacts with HAX1, EIF3G and SRPX proteins and that this interaction occurs at the cytoskeleton; this interaction may facilitate PELO to detect and degrade aberrant mRNAs.
Death receptor signal transducers: nodes of coordination in immune signaling networks.
Ashkenazi et al., San Francisco, United States. In Nat Immunol, 2009
Death receptors (DRs) are members of the tumor necrosis factor receptor superfamily that possess a cytoplasmic death domain (DD).
ETX1 is over-expressed in the glaucomatous trabecular meshwork.
Bhattacharya et al., Miami, United States. In Mol Vis, 2008
This is the first report demonstrating overexpression of ETX1 in glaucomatous trabecular meshwork.
Human CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndrome.
Engle et al., Boston, United States. In Science, 2008
Duane's retraction syndrome (DRS) is a complex congenital eye movement disorder caused by aberrant innervation of the extraocular muscles by axons of brainstem motor neurons.
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