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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Developmental pluripotency associated 2

Dppa2, CT100, developmental pluripotency associated-2
Top mentioned proteins: DPPA4, Nanog, Sox2, CAN, APP
Papers on Dppa2
Effect of primary culture medium type for culture of canine fibroblasts on production of cloned dogs.
Lee et al., Seoul, South Korea. In Theriogenology, Oct 2015
Donor cells cultured in RCMEp contained a significantly higher amount of SOX2, NANOG, DPPA2, REXO1, HDAC, DNMT1, MECP2 and telomerase activity than those cultured in DMEM (P < 0.05).
Early reprogramming regulators identified by prospective isolation and mass cytometry.
Wernig et al., Stanford, United States. In Nature, Jun 2015
Expression profiling reveals early upregulation of the transcriptional regulators Nr0b1 and Etv5 in this reprogramming state, preceding activation of key pluripotency regulators such as Rex1 (also known as Zfp42), Dppa2, Nanog and Sox2.
Tissue-specific somatic stem-cell isolation and characterization from human endometriosis. Key roles in the initiation of endometrial proliferative disorders.
Ghanbari et al., Tehrān, Iran. In Minerva Med, Apr 2015
Spindle-like morphology, normal karyotype, adipogenic and osteogenic potential, significantly expression of Oct4, SALL4, DPPA2, Sox2, Sox17 and also specific surface markers such as CD44, CD105, CD90, CD73 and CD146 in EESCs and ELSCs was observed.
LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration.
Wang et al., Hong Kong, Hong Kong. In Cell Res, Mar 2015
Here we identify an lncRNA, Dum (developmental pluripotency-associated 2 (Dppa2) Upstream binding Muscle lncRNA) in skeletal myoblast cells.
Diagnostic clinical relevance of developmental pluripotency-associated 2 (DPPA2) in colorectal cancer.
Forghanifard et al., Mashhad, Iran. In Int J Surg, 2015
One of the newly identified pluripotency genes which is expressed specifically in pluripotent stem cells is developmental pluripotency-associated 2 (DPPA2).
Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry.
Poot et al., Rotterdam, Netherlands. In Nat Commun, 2014
A quarter of the identified factors are important for pluripotency and includes Oct4, Esrrb, Klf5, Mycn and Dppa2, factors that drive reprogramming to pluripotent stem cells.
DPPA2 Protein Expression is Associated with Gastric Cancer Metastasis.
Forghanifard et al., Mashhad, Iran. In Asian Pac J Cancer Prev, 2014
Developmental pluripotency associated-2 (DPPA2), cancer-testis antigen (CT100), is commonly expressed only in the human germ line and pluripotent embryonic cells but it is also present in a significant subset of malignant tumors.
Progress on ovine lentivirus and its resistant genes.
Wang et al., Hangzhou, China. In Yi Chuan, 2014
Here, we review the progress of E35K mutation in sheep TMEM154 gene and its effects on resistance to MVV, and other lentivirusresistant genes including zinc finger cluster, chemokine reveptor 5 (CCR5), tripartite motif-containing 5 alpha (TRIM5Α), apolipoprotein B mRNA-editing catalytic polypetide like 3 (APOBEC3), developmental pluripotencyassociated 2 (DPPA2) and DPPA4.
Aberrant expression of DPPA2 and HIWI genes in colorectal cancer and their impacts on poor prognosis.
Forghanifard et al., Mashhad, Iran. In Tumour Biol, 2014
Developmental pluripotency factor 2 (DPPA2) and HIWI are two important developmental genes which are involved in embryonic and germ line stem cell properties.
Importin β-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts.
Yan et al., Charlotte, United States. In Cell Signal, 2014
We then demonstrated that TopBP1's C-terminal motif (designated as CTM, 23 amino acids) containing a putative NLS (nuclear localization signal) was required for Importin β interaction and that CT100 of Importin β (100 amino acids of extreme C-terminus of Importin β) was required for TopBP1 interaction.
Nuclear assembly shaped by microtubule dynamics.
Funabiki et al., New York City, United States. In Nucleus, 2014
Here we discuss our recent study of nuclear assembly in Xenopus egg extracts, where we showed that the DNA binding protein Developmental pluripotency associated 2 (Dppa2) directly inhibits microtubule polymerization during nuclear formation, and that this is essential for normal nuclear shape and replication.
Making gametes from pluripotent stem cells--a promising role for very small embryonic-like stem cells.
Bhilawadikar et al., Mumbai, India. In Reprod Biol Endocrinol, 2013
Both VSELs and PGCs are pluripotent, relatively quiescent because of epigenetic modifications of parentally imprinted genes loci like Igf2-H19 and KCNQ1p57, share several markers like Stella, Fragilis, Mvh, Dppa2, Dppa4, Sall4, Blimp1 and functional receptors.
Sculpting the nucleus with dynamic microtubules.
Zheng et al., Baltimore, United States. In Dev Cell, 2013
(2013) demonstrate that Dppa2, a chromatin-bound microtubule regulator, controls both the morphology and function of the pronucleus by fine-tuning microtubule dynamics.
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase.
Jaenisch et al., Cambridge, United States. In Cell, 2012
Expression of Esrrb, Utf1, Lin28, and Dppa2 is a better predictor for cells to progress into iPSCs than expression of the previously suggested reprogramming markers Fbxo15, Fgf4, and Oct4.
Essential roles of ECAT15-2/Dppa2 in functional lung development.
Yamanaka et al., Kyoto, Japan. In Mol Cell Biol, 2011
has important roles in lung development, where it is no longer expressed, by leaving epigenetic marks from earlier developmental stages
Dppa2 knockdown-induced differentiation and repressed proliferation of mouse embryonic stem cells.
Lu et al., Changsha, China. In J Biochem, 2010
Results showed that the expression of Dppa2 decreased markedly in differentiated cells. Dppa2 might play a role in maintenance of the undifferentiated state and proliferation of ES cells
Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer.
Odunsi et al., Buffalo, United States. In Cancer Immun, 2008
In normal tissues, PLAC1 expression was restricted to the placenta while DPPA2 expression was restricted to the placenta and testis.
ECSA/DPPA2 is an embryo-cancer antigen that is coexpressed with cancer-testis antigens in non-small cell lung cancer.
Cebon et al., Melbourne, Australia. In Clin Cancer Res, 2008
ECSA/DPPA2 is a promising target for antigen-specific immunotherapy in non-small cell lung cancers
Differential expression of the embryo/cancer gene ECSA(DPPA2), the cancer/testis gene BORIS and the pluripotency structural gene OCT4, in human preimplantation development.
Hawes et al., London, United Kingdom. In Mol Hum Reprod, 2008
Differential expression of the embryo/cancer gene ECSA(DPPA2) in human preimplantation development.
Pathophysiological roles of amyloidogenic carboxy-terminal fragments of the beta-amyloid precursor protein in Alzheimer's disease.
Suh et al., Seoul, South Korea. In J Pharmacol Sci, 2005
Spatial memory of transgenic (Tg) mice overexpressing CT100 was significantly impaired and CTFs were detected in the neurons as well as in plaques of the Tg mice and double Tg mice carrying CT100 and mutant tau.
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