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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.


The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, CAN, ACID, TH2, V1a
Papers using D10 antibodies
Nuclear Factor of Activated T Cells Balances Angiogenesis Activation and Inhibition
Volpert Olga V. et al., In The Journal of Experimental Medicine, 1997
... Redondo, Universidad Autonoma de Madrid, Madrid, Spain) for immunoblots and NFATc2 mouse mAb G1-D10 (Santa Cruz Biotechnology, Inc.) for immunostaining ...
Papers on D10
Creatine supplementation prevents hyperhomocysteinemia, oxidative stress and cancer-induced cachexia progression in Walker-256 tumor-bearing rats.
Guarnier et al., Londrina, Brazil. In Amino Acids, Feb 2016
First, rats were killed on days 5 (D5), 10 (D10) and 14 (D14) after tumor implantation.
Development of a Carbon Mesh Supported Thin Film Microextraction Membrane As a Means to Lower the Detection Limits of Benchtop and Portable GC/MS Instrumentation.
Pawliszyn et al., Waterloo, Canada. In Anal Chem, Feb 2016
With the use of hand-portable GC-TMS instrumentation, membranes cut with dimensions 40 mm long by 4.85 mm wide and 40 ± 5 μm thick (per side) were shown to extract 21.2, 19.8, 18.5, 18,4, 26.8, and 23.7 times the amount of 2,4 dichlorophenol, 2,4,6 trichlorophenol, phorate D10, fonofos, chloropyrifos, and parathion, respectively, within 15 min from a 10 ppb aqueous solution as compared to a 65 μm DVB/PDMS solid phase microextraction (SPME) fiber.
Sympathoexcitation in Rats With Chronic Heart Failure Depends on Homeobox D10 and MicroRNA-7b Inhibiting GABBR1 Translation in Paraventricular Nucleus.
Lai et al., Siping, China. In Circ Heart Fail, Jan 2016
We hypothesized that ANG II regulates sympathoexcitation through homeobox D10 (HoxD10), which regulates miR-7b in other tissues.
Effect of X-irradiation on Citrus Canker Pathogen Xanthomonas citri subsp. citri of Satsuma Mandarin Fruits.
Jeun et al., Cheju, South Korea. In Plant Pathol J, Dec 2015
The D10 value for Xcc on citrus fruits was found to be 97 Gy, indicating the possibility of direct application on citrus quarantine without any side sterilizer.
[Mechanism of dwarfing effect of tomato (Solanum lycopersicon) seedlings inducec by cold-shock treatment under high temperature stress].
Sun et al., In Ying Yong Sheng Tai Xue Bao, Jul 2015
Plant height, ethylene production and gibberellin (GA3) content of the seedlings treated with T10 °C D10 min (cold-shock with 10 °C for 10 min), coupled with utilization of growth regulators, were also evaluated.
Subarachnoidal-pleural fistula (SAPF) as an unusual cause of persistent pleural effusion. Beta-trace protein as a marker for SAPF. Case report and review of the literature.
Malfait et al., In Acta Clin Belg, Feb 2015
BACKGROUND: We describe a case of a 56-year-old woman who developed a recurrent pleural effusion after a thoracoscopic resection of an anterior bulging thoracic disc hernia (level D9-D10).
[Elusive thoracic spine tumour. Report of an exceptional case and literature review].
Ortega-Martínez et al., Badajoz, Spain. In Neurocirugia (astur), 2015
We present the case of a woman with a preoperative radiological diagnosis of schwannoma at D10 level in whom a laminectomy was performed to remove the tumour.
Combined Effect of Irradiation and Ageing Condition on Physicochemical and Microbial Quality of Hanwoo Eye of Round.
Nam et al., Chinju, South Korea. In Korean J Food Sci Anim Resour, 2014
The population of Listeria monocytogenes and E. coli O157:H7 inoculated in beef samples decreased in proportion to the irradiation dose, showing D10 values of 0.66 and 0.65 kGy respectively.
Primary myoepithelioma of the dorsal spine: a case report and review of literature.
Salunke et al., Chandīgarh, India. In Spine (phila Pa 1976), 2014
METHODS: A 50-year male, presenting with complaints of paraparesis and difficulty in walking, was diagnosed to have an expansile lytic lesion involving the D10 vertebral body with paraspinal extension.
Aneurysmal bone cyst of thoracic spine: case report and brief review of literature.
Shukla et al., Lucknow, India. In Bmj Case Rep, 2012
A 16-year-old girl was admitted with insidious onset, gradually progressive spastic sensori-motor paraparesis, with a sensory level at D10 dermatome without bowel or bladder involvement for the last 2 months following trivial trauma on the lower back.
Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia.
Russo et al., Roma, Italy. In Curr Drug Targets, 2012
evidence on the association between variations in CHRNA7 or CHRFAM7A and the risk of dementia is still sparse and inconclusive. Further studies are needed to establish whether some polymorphisms may affect the probability of developing dementia [review]
Dual gliomas with syringomyelia in a child: case report and literature review.
Challa et al., Hyderābād, India. In Pediatr Neurosurg, 2011
Recent MRI brain and spine scans showed a small residual lesion at the hypothalamus with D1 to D10 syrinx.
Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS.
Fornasari et al., Milano, Italy. In J Neuroimmunol, 2011
the partially duplicated alpha7 nAChR subunit gene may specifically participate in the inflammatory response of the innate immune system.
CHRFAM7A copy number and 2-bp deletion polymorphisms and antisaccade performance.
Ettinger et al., Bonn, Germany. In Int J Neuropsychopharmacol, 2009
No significant associations of 2-bp deletion or CHRFAM7A copy number with antisaccade performance parameters were observed.
Differentiating nicotine- versus schizophrenia-associated decreases of the alpha7 nicotinic acetylcholine receptor transcript, CHRFAM7A, in peripheral blood lymphocytes.
Yolken et al., Baltimore, United States. In J Neural Transm, 2009
In 20 smoking-matched people (n = 10 schizophrenia, n = 10 controls), we found significantly lower CHRFAM7A in cotinine and self-reported smokers versus nonsmokers (p
Association between a genetic variant of the alpha-7 nicotinic acetylcholine receptor subunit and four types of dementia.
Janka et al., Szeged, Hungary. In Dement Geriatr Cogn Disord, 2008
polymorphism of CHRFAM7A can be implicated in Alzheimer's disease, dementia with Lewy bodies and Pick's disease
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer.
Weinberg et al., Cambridge, United States. In Nature, 2007
The miR-10b induced by Twist proceeds to inhibit translation of the messenger RNA encoding homeobox D10, resulting in increased expression of a well-characterized pro-metastatic gene, RHOC.
The crystal structure of a T cell receptor in complex with peptide and MHC class II.
Wang et al., Boston, United States. In Science, 2000
The crystal structure of a complex involving the D10 T cell receptor (TCR), 16-residue foreign peptide antigen, and the I-Ak self major histocompatibility complex (MHC) class II molecule is reported at 3.2 angstrom resolution.
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells.
Flavell et al., New Haven, United States. In Cell, 1997
Antisense GATA-3 inhibited the expression of all Th2 cytokine genes in the Th2 clone D10.
Transmission of in-vitro radioresistance in a cancer-prone family.
Paterson et al., In Lancet, 1981
The D10 value (radiation dose required to reduce survival to 10%) was significantly higher for the five radioresistant strains (491 +/- 30 rad) than for control cultures (405 +/- 18 rad).
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