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Chorionic somatomammotropin hormone-like 1

CS5, hCS-L, CS-L
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] (from NCBI)
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Top mentioned proteins: CS2, HAD, CAN, ACID, AGE
Papers on CS5
Diagnostic performance of skeletal maturity for the assessment of midpalatal suture maturation.
McNamara et al., São Bernardo do Campo, Brazil. In Am J Orthod Dentofacial Orthop, Dec 2015
RESULTS: Positive LHRs greater than 10 were found for several cervical vertebral stages (CSs), including CS1 and CS2 for the identification of midpalatal suture stages A and B, CS3 for the diagnosis of midpalatal suture stage C, and CS5 for the assessment of midpalatal suture stages D and E. These positive LHRs indicated large and often conclusive increases in the likelihood that the CVM stages were associated with specific stages of midpalatal suture maturation.
Interaction between mDia1 and ROCK in Rho-induced migration and adhesion of human dental pulp cells.
Hu et al., Chengdu, China. In Int Endod J, Dec 2015
Phosphorylation of focal adhesion kinase (FAK) and paxillin was detected by western blotting and the bands were analyzed using Adobe Photoshop CS5 software (Adobe Systems, San Jose, CA, USA).
Perception of Aesthetics by Different Professionals of Different Communities.
Gangurde et al., Mumbai, India. In J Clin Diagn Res, Oct 2015
These photographs were then subjected to changes in increments of 2 mm and 4 mm in retrusive and protrusive profile in Adobe Photoshop CS5 after which they were evaluated by different professionals of different communities according to their preference from most liked to least liked.
[Study on the difference of corresponding age at cervical vertebral maturation stages among different skeletal malocclusions].
Gu et al., Beijing, China. In Zhonghua Kou Qiang Yi Xue Za Zhi, Oct 2015
RESULTS: Significant gender difference of age was found at CS3 to CS6 for skeletal Class I group (P < 0.05), at CS5 and CS6 for skeletal Class II group (P < 0.05), and at CS3 and CS5 for skeletal Class III group (P < 0.05).
Infraocclusion: Dental development and associated dental variations in singletons and twins.
Brook et al., Adelaide, Australia. In Arch Oral Biol, Sep 2015
Adobe Photoshop CS5 was used to construct reference lines and measure the extent of infraocclusion (in mm) of primary molars on the panoramic radiographs and on 2D images obtained from the dental models.
Retrospective analysis of community hospital red blood cell recovery procedures: improved utilization needed for effectiveness.
Shi et al., Birmingham, United States. In Transfusion, Aug 2015
Linear regression demonstrated significant association of rRBCs with increased EBL, longer operative duration, surgeon, PBR device type (autoLog vs. CS5), and decreasing age.
Color stability of mineral trioxide aggregate and calcium enriched mixture cement.
Asgary et al., Tehrān, Iran. In J Investig Clin Dent, Aug 2015
Commission Internationale de I'E'clairage (CIE) color space system and Photoshop CS5 software were used to evaluate the discoloration.
Prevalence of infraocclusion of primary molars determined using a new 2D image analysis methodology.
Brook et al., Adelaide, Australia. In Aust Dent J, Aug 2015
Adobe Photoshop CS5 was used to measure the extent of infraocclusion.
Sleep disorders in pregnancy and their association with pregnancy outcomes: a prospective observational study.
Vedita et al., New Delhi, India. In Sleep Breath, Jun 2015
and 2.9 (95 % CI 1.0-8.2) and for undergoing CS-5.3 (95 % CI 1.7-16.3),
Reliability and Validity of the Footprint Assessment Method Using Photoshop CS5 Software.
Guerra-Balic et al., In J Am Podiatr Med Assoc, May 2015
We sought to assess the reliability and validity of a new method of footprint assessment in a healthy population using Photoshop CS5 software (Adobe Systems Inc, San Jose, California).
Serum insulin-like growth factor-1 levels in females and males in different cervical vertebral maturation stages.
Jain et al., Indore, India. In Dental Press J Orthod, Mar 2015
The highest mean IGF-1 levels in males was observed in CS4 followed by CS5 and third highest in CS3; whereas in females the highest mean IGF-1 levelswas observed in CS3 followed by CS4 and third highest in CS5.
Click Grafting of Alkyne-containing Vinyl Polymers onto Biosynthesized Extracellular Matrix Protein Containing Azide Functionality and Adhesion Control of Human Umbilical Vein Endothelial Cells.
Takasu et al., Nagoya, Japan. In Rsc Adv, 2015
UNASSIGNED: In vivo incorporation of a phenylalanine (Phe) analogue, p-azidophenylalanine (p-N3Phe) into an artificial extracellular matrix protein (aECM-CS5-ELF) was accomplished using a bacterial expression host that harbors the mutant phenylalanyl-tRNA synthetase (PheRS) with an enlarged binding pocket, in which the Ala294Gly/Thr251Gly mutant PheRS (PheRS**) was expressed under the control of T7 promoters.
Genetic fusions of a CFA/I/II/IV MEFA (multiepitope fusion antigen) and a toxoid fusion of heat-stable toxin (STa) and heat-labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC) retain broad anti-CFA and antitoxin antigenicity.
Zhang et al., Baltimore, United States. In Plos One, 2014
CFA MEFA CFA/I/II/IV [CVI 2014, 21(2):243-9], which carried epitopes of seven CFAs [CFA/I, CFA/II (CS1, CS2, CS3), CFA/IV (CS4, CS5, CS6)] expressed by the most prevalent and virulent ETEC strains, was genetically fused to LT-STa toxoid fusion monomer 3xSTaA14Q-dmLT or 3xSTaN12S-dmLT [IAI 2014, 82(5):1823-32] for CFA/I/II/IV-STaA14Q-dmLT and CFA/I/II/IV-STaN12S-dmLT MEFAs.
Regulation of the human growth hormone gene family: possible role for Pit-1 in early stages of pituitary-specific expression and repression.
Detillieux et al., Winnipeg, Canada. In Neuroendocrinology, 2005
The GH/CS gene family consists of five genes (GH-N, GH-V, CS-A, CS-B and CS-L), contained in a single locus on chromosome 17.
[hGH and molecular biology].
Goossens, In Ann Endocrinol (paris), 1985
The growth hormone gene is part of a family of five structural genes located on the long arm of human chromosome 17, over a distance of 55 kilobases (kb), and oriented in the same transcriptional 5' to 3' direction in the order 5' hGH-N, hCS-L, hCS-A, hGH-V, and hCS-B 3'.
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