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Chorionic somatomammotropin hormone 2

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, ACID, HAD, fibrillin-1, V1a
Papers on CS2
Phenolate based metallomacrocyclic xanthate complexes of Co(II)/Cu(II) and their exclusive deployment in [2 : 2] binuclear N,O-Schiff base macrocycle formation and in vitro anticancer studies.
Mobin et al., Vadodara, India. In Dalton Trans, Feb 2016
The reaction of or with M(OAc)2 in Et3N affords access to a rare series of binuclear metallomacrocyclic xanthate complexes of the type [M2-μ(2)-bis-(κ(2)S,S-xan(1)/xan(2))] () which quickly forms [2 : 2] binuclear N,O-bidentate Schiff base macrocyclic complexes of the type [M2-μ(2)-bis-(κ(2)N,O-L(1)/L(2))] ( = 4,4'-bis(2-hydroxybenzylideneamino)diphenyl ether, = 4,4'-bis(2-hydroxynaphthylmethylidene-amino)diphenyl ether) via evolution of CS2 in solution.
An insight into the interaction of L-proline with the transition metal cations Fe(2+), Co(2+), Ni(2+): a gas phase theoretical study.
Khalili, Rasht, Iran. In J Mol Model, Jan 2016
Three modes of interaction have been considered: salt bridged (SB), involving binding in a bi-dentate manner through the carboxylate group of L-proline, charge solvated 1 (CS1) involving carbonyl and hydroxyl oxygen, and charge solvated 2 (CS2) involving carbonyl oxygen and the lone pair of the nitrogen atom.
A simple and efficient method for cryopreservation and recovery of viable Plasmodium vivax and P. falciparum sporozoites.
Adams et al., Tampa, United States. In Parasitol Int, Jan 2016
Significant differences were observed among the cryopreservation media and protocols evaluated, with CryoStor CS2 giving the best results for both P. falciparum and P. vivax, whereas Hestar 200 worked efficiently only for P. vivax sporozoites.
[Resonance Raman Spectral Properties Studies of Beta-carotene in Solution].
Li et al., In Guang Pu Xue Yu Guang Pu Fen Xi, Jul 2015
In-situ high pressure Raman spectra of beta-carotene are measured in CS2 solution and water respectively at pressure range from 0-0.60 GPa.
[Preparation of Rubber Accelerator Tetramethyl Thiuram Monosulfide and Its Spectral Analysis].
Jin et al., In Guang Pu Xue Yu Guang Pu Fen Xi, Jul 2015
The results of TG-DSC and FTIR showed that single crystal TMTM possessed with little CS2.
Carbon Disulfide (CS2) Mechanisms in Formation of Atmospheric Carbon Dioxide (CO2) Formation from Unconventional Shale Gas Extraction and Processing Operations and Global Climate Change.
Patel et al., Fort Worth, United States. In Environ Health Insights, 2014
Carbon disulfide (CS2) has been historically associated with the production of rayon, cellophane, and carbon tetrachloride.
A review of developmental and reproductive toxicity of CS2 and H2 S generated by the pesticide sodium tetrathiocarbonate.
Silva, Sacramento, United States. In Birth Defects Res B Dev Reprod Toxicol, 2013
BACKGROUND: Sodium tetrathiocarbonate (STTC) is an example of a pesticide that when prepared for use in aqueous solution releases two toxic products carbon disulfide (CS2 ) (active ingredient) and hydrogen sulfide (H2 S) in ambient air in equimolar concentrations resulting in potential exposure to workers and bystanders.
Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.
Laan et al., Tartu, Estonia. In Mol Cell Endocrinol, 2012
results are consistent with a pleiotropic effect of placental hGH/CSH genes at the maternal-fetal interface relating to the regulation of fetal growth and the risk of affected maternal metabolism.
The role of memory-related gene polymorphisms, KIBRA and CLSTN2, on replicate memory assessment in the elderly.
Krugluger et al., Vienna, Austria. In J Neural Transm, 2012
No increased risk of any type of late development, and cognitive impairment was associated with CLSTN2 (rs6439886)
Identification of functional CCAAT/enhancer-binding protein and Ets protein binding sites in the human chorionic somatomammotropin enhancer sequences.
Cattini et al., Winnipeg, Canada. In J Mol Endocrinol, 2011
Data conclude that members of the C/EBP and Ets families can differentially modulate CS-Benh and CS-Aenh activity.
KIBRA and CLSTN2 polymorphisms exert interactive effects on human episodic memory.
Bäckman et al., Berlin, Germany. In Neuropsychologia, 2010
This study showed that the KIBRA and CLSTN2 genes interactively modulate episodic memory performance.
The eye--a neglected organ in environmental and occupational medicine: an overview of known environmental and occupational non-traumatic effects on the eyes.
Godnić-Cvar et al., Vienna, Austria. In Arh Hig Rada Toksikol, 2009
Investigations of retinal vascular changes and retinopathy after chronic exposure to carbon disulfide (CS2) and of retinal and choroidal haemodynamics after exposure to carbon monoxide (CO) found that CS2 caused an increase in retinal venous diameters and CO caused an increase in arterial and venous diameters, retinal blood flow velocity, and fundus pulsation amplitude.
Time-resolved molecular frame dynamics of fixed-in-space CS2 molecules.
Stolow et al., Ottawa, Canada. In Science, 2009
Random orientation of molecules within a sample leads to blurred observations of chemical reactions studied from the laboratory perspective.
Candidate-gene testing for orphan limb-girdle muscular dystrophies.
Nigro et al., Napoli, Italy. In Acta Myol, 2008
A large number of variations were found in many of the genes (myozenin 1, gamma-filamin, kinectin-1) in patients with limb-girdle muscular dystrophies and controls.
[Effects of volcanic eruptions on environment and health].
Milosević et al., Zagreb, Croatia. In Arh Hig Rada Toksikol, 2007
Along with magma and steam (H2O), the following gases surface in the environment: carbon dioxide (CO2) and sulphur dioxide (SO2), carbon monoxide (CO), hydrogen sulphide (H2S), carbon sulphide (CS), carbon disulfide (CS2), hydrogen chloride (HCl), hydrogen (H2), methane (CH4), hydrogen fluoride (HF), hydrogen bromide (HBr) and various organic compounds, as well as heavy metals (mercury, lead, gold).Their unfavourable effects depend on the distance from a volcano, on magma viscosity, and on gas concentrations.
Behavioral toxicology: from historical background to future trends.
Iregren, Stockholm, Sweden. In Med Lav, 2006
Among the first publications were those of Helena Hänninen, who reported on exposure to CS2 (24, 22).
The formation of HCS and HCSH molecules and their role in the collision of comet Shoemaker-Levy 9 with Jupiter.
Lee et al., Berkeley, United States. In Science, 1998
In the shocked jovian atmosphere, HCS could further decompose to H and CS, and CS could react with SH and OH to yield the observed CS2 and COS.
The activity and size of the nucleus of comet Hale-Bopp (C/1995 O1) [see comment].
Tozzi et al., Baltimore, United States. In Science, 1997
The International Ultraviolet Explorer and HST spectra showed emissions from OH (a tracer of H2O) and CS (a tracer of CS2) starting in April 1996, and from the CO Cameron system (which primarily traces CO2) starting in June 1996.
Photopolymerization and Mass-Independent Sulfur Isotope Fractionations in Carbon Disulfide
Trogler et al., San Diego, United States. In Science, 1996
Irradiation of gaseous carbon disulfide [CS2(g)] at 313 nanometers produces a dark brown aerosol of (CS2)x.
HST spectroscopic observations of Jupiter after the collision of comet Shoemaker-Levy 9.
Edgington et al., Baltimore, United States. In Science, 1995
The large mass of sulfur-containing material, more than 10(14) grams in S2 alone, indicates that many of the sulfur-containing molecules S2, CS2, CS, H2S, and S+ may be derived from a sulfur-bearing parent molecule native to Jupiter.
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