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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Dihydropyrimidinase-like 4

CRMP3, Ulip4, collapsin response mediator protein-3, DRP-4
protein that may regulate neuronal plasticity by transducing signals from semaphorins [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CRMP-2, Ulip, CRMP5, ACID, Calpain
Papers on CRMP3
Mapping CRMP3 domains involved in dendrite morphogenesis and voltage-gated calcium channel regulation.
Duchemin et al., Lyon, France. In J Cell Sci, 2013
In our previous studies, we deleted the gene encoding CRMP3 in mice and identified the protein as a new endogenous signaling molecule that shapes diverse features of the hippocampal pyramidal dendrites without affecting axon morphology.
Collapsin response mediator protein 3 deacetylates histone H4 to mediate nuclear condensation and neuronal death.
Zhou et al., Ottawa, Canada. In Sci Rep, 2012
Here we found that mouse CRMP3 has robust histone H4 deacetylase activity.
Activation of CRHR2 exerts an inhibitory effect on the expression of collapsin response mediator protein 3 in hippocampal neurons.
Ni et al., Shanghai, China. In Neuropeptides, 2012
However, effects of CRH receptors activation on collapsin response mediator protein 3 (CRMP3), the key protein for dendrite outgrowth and cell apoptosis, remain unclear.
Identification of dihydropyrimidinase-related protein 4 as a novel target of the p53 tumor suppressor in the apoptotic response to DNA damage.
Yoshida et al., Tokyo, Japan. In Int J Cancer, 2011
DPYSL4 is a novel apoptosis-inducible factor controlled by p53 in response to DNA damage
Characterization of the role of full-length CRMP3 and its calpain-cleaved product in inhibiting microtubule polymerization and neurite outgrowth.
Hou et al., Ottawa, Canada. In Exp Cell Res, 2009
Data show CRMP3's role in attenuating neurite outgrowth possibility through inhibiting microtubule polymerization, and also reveal its novel association with vimentin during nuclear condensation prior to neuronal death.
Calpain-truncated CRMP-3 and -4 contribute to potassium deprivation-induced apoptosis of cerebellar granule neurons.
Li et al., Guangzhou, China. In Proteomics, 2009
The findings demonstrated that calpain-truncated CRMP-3 and -4 act as pro-apoptotic players when CGNs undergo apoptosis.
CRMP3 is required for hippocampal CA1 dendritic organization and plasticity.
Kolattukudy et al., Lyon, France. In Faseb J, 2008
indicate an important role for CRMP3 in dendrite arborization, guide-posts navigation, and neuronal plasticity
Calpain cleavage of collapsin response mediator proteins in ischemic mouse brain.
Hou et al., Ottawa, Canada. In Eur J Neurosci, 2007
Our previous studies have shown that calpain cleaves CRMP3 in the adult mouse brain during cerebral ischemia [S.T. Hou et al. (2006) J. Neurosci., 26, 2241-2249].
Antibodies to CRMP3-4 associated with limbic encephalitis and thymoma.
Vedeler et al., Bergen, Norway. In Clin Exp Immunol, 2007
Screening a cDNA expression library identified collapsin response mediator protein 3 (CRMP3), a protein involved in neurite outgrowth.
Calpain-cleaved collapsin response mediator protein-3 induces neuronal death after glutamate toxicity and cerebral ischemia.
Kappler et al., Ottawa, Canada. In J Neurosci, 2006
Collectively, these results reveal a novel role of CRMP-3 in that calpain cleavage of CRMP-3 and the subsequent nuclear translocation of the truncated CRMP-3 evokes neuronal death in response to excitotoxicity and cerebral ischemia.
Expression of collapsin response mediator proteins in the nervous system of embryonic zebrafish.
Becker et al., Hamburg, Germany. In Gene Expr Patterns, 2005
CRMPs are evolutionarily conserved and zebrafish CRMPs show amino acid identities of 76-90% with their homologs in humans, with the exception of CRMP-3, which shows only 67% homology.
Age-dependent expression of collapsin response mediator proteins (CRMPs) in cat visual cortex.
Arckens et al., Leuven, Belgium. In Eur J Neurosci, 2004
While CRMP3 could not be detected in cat forebrain, the other CRMPs showed a higher expression in the immature brain compared to the adult state.
Expression of axon guidance molecules and their related genes during development and sexual differentiation of the olfactory bulb in rats.
Wong et al., Hong Kong, Hong Kong. In Neuroscience, 2003
Sex differences of semaphorin 3A, neuropilin-1 as well as collapsin response mediator protein 3 at the early development stage and the late effect of neonatal testosterone propionate treatment on the expressions of netrin-1, growth-associated marker protein, cypin and collapsin response mediator proteins 1, 3 and 5 genes may indicate a possible role of these molecules on sexual differentiation of the olfactory bulb.
Collapsin response mediator protein-2 accelerates axon regeneration of nerve-injured motor neurons of rat.
Kiyama et al., Ōsaka, Japan. In J Neurochem, 2003
Among the members, CRMP-1, CRMP-2, CRMP-5 mRNA expressions increased after nerve injury, whereas CRMP-3 and CRMP-4 mRNA did not show any significant change.
CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity.
Lennon et al., Rochester, United States. In Ann Neurol, 2001
Serum IgG in all cases bound to recombinant CRMP-5 (predominantly N-terminal epitopes), but not to human CRMP-2 or CRMP-3.
Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain.
Lubec et al., Vienna, Austria. In J Neural Transm Suppl, 2000
Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain.
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