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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

CRAG, Mrip1
Top mentioned proteins: HAD, V1a, CsF, Histone, Ubiquitin
Papers on CRAG
Evaluation of fingerstick cryptococcal antigen lateral flow assay in HIV-infected persons: a diagnostic accuracy study.
Boulware et al., Kampala, Uganda. In Clin Infect Dis, Sep 2015
The cryptococcal antigen (CRAG) lateral flow assay (LFA) has simplified diagnosis as a point-of-care test approved for serum or cerebrospinal fluid (CSF).
Compatibility of a novel thrombospondin-1 analog with fertility and pregnancy in a xenograft mouse model of endometriosis.
Tayade et al., Kingston, Canada. In Plos One, 2014
Endometriosis was induced using human endometrium in β-estradiol-primed BALB/c-Rag-2-/-Il2rγ-/- mice receiving intraperitoneal injections of ABT-898 (25 mg/kg) or 5% dextrose control for 21 days.
Detection of High Cerebrospinal Fluid Levels of (1→3)-β-d-Glucan in Cryptococcal Meningitis.
Boulware et al., Kampala, Uganda. In Open Forum Infect Dis, 2014
Correlations between BDG concentrations and quantitative CSF cryptococcal cultures, CSF cryptococcal antigen (CRAG) titers, and 18 different CSF cytokine concentrations were assessed using non-parametric tests.
Polarized deposition of basement membrane proteins depends on Phosphatidylinositol synthase and the levels of Phosphatidylinositol 4,5-bisphosphate.
Schüpbach et al., Princeton, United States. In Proc Natl Acad Sci U S A, 2014
In addition, PIP2 controls the apical and lateral localization of Crag (Calmodulin-binding protein related to a Rab3 GDP/GTP exchange protein), a factor specifically required to prevent aberrant apical secretion of BM.
Mutant ataxin-3 with an abnormally expanded polyglutamine chain disrupts dendritic development and metabotropic glutamate receptor signaling in mouse cerebellar Purkinje cells.
Hirai et al., Maebashi, Japan. In Cerebellum, 2014
To confirm that the defects in SCA3 mice were caused by postnatal deposition of mutant ataxin-3 in PCs, not by genome disruption via transgene insertion, we tried to reduce the accumulation of mutant ataxin-3 in developing PCs by viral vector-mediated expression of CRAG, a molecule that facilitates the degradation of stress proteins.
A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis.
Horne-Badovinac et al., Chicago, United States. In Dev Cell, 2013
Next, Crag targets Rab10 to structures in the basal cytoplasm, where it restricts protein delivery to the basal surface.
Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells.
Bellen et al., Houston, United States. In Plos Biol, 2011
Here, we show that Crag, a DENN protein, is a guanine nucleotide exchange factor for Rab11 that is required for the homeostasis of Rh1 upon light exposure.
CRMP5-associated GTPase (CRAG) protein protects neuronal cells against cytotoxicity of expanded polyglutamine protein partially via c-Fos-dependent activator protein-1 activation.
Yanagi et al., United States. In J Biol Chem, 2011
CRAG enhances the cell survival signal against the accumulation of unfolded proteins, including polyQ, through not only proteasome activation, but also the activation of c-Fos-dependent AP-1.
UMA and MABP domains throw light on receptor endocytosis and selection of endosomal cargoes.
Aravind et al., Bethesda, United States. In Bioinformatics, 2010
The MABP domain present in metazoan ESCRT-I/MVB12 subunits, Crag, a regulator of protein sorting, and bacterial pore-forming proteins might mediate novel membrane interactions in trafficking.
Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: a prospective cohort study.
Bohjanen et al., Minneapolis, United States. In Plos Med, 2009
Patients experiencing subsequent CM-IRIS had 4-fold higher median serum cryptococcal antigen (CRAG) levels pre-ART (p = 0.006).
Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice.
Silver et al., London, United Kingdom. In Plos One, 2008
These were defined as Mom (Modifier of Min) radiation-induced polyposis (Mrip1-5) on chromosome 2 (log of odds, LOD 2.8, p = 0.0003), two regions within chromosome 5 (LOD 5.2, p<0.00001, 6.2, p<0.00001) and two regions within chromosome 16 respectively (LOD 4.1, p = 4x10(-5), 4.8, p<0.00001).
Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.
Hirai et al., Maebashi, Japan. In Embo Rep, 2008
Previously, we identified a new guanosine triphosphatase, CRAG, which facilitates the degradation of polyQ aggregates through the ubiquitin-proteasome pathway in cultured cells.
Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila.
Schüpbach et al., Princeton, United States. In Dev Cell, 2008
In a genetic screen in the Drosophila follicular epithelium, we identified mutations in Crag, which encodes a conserved protein with domains implicated in membrane trafficking.
Critical role of dendritic cells in determining the Th1/Th2 balance upon Leishmania major infection.
Koyasu et al., Tokyo, Japan. In Int Immunol, 2008
By using bone marrow (BM) chimeras generated by the transplantation of B10.D2 BM cells into BALB/c-Rag-2(-/-) mice, and vice versa, it was shown that hematopoietic cells carry factors determining the disease outcome and T(h)1 response against L. major infection.
A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein.
Yanagi et al., Hachiōji, Japan. In J Cell Biol, 2006
We propose that CRAG is a modulator of promyelocytic leukemia protein function and dynamics in reactive oxygen species signaling and is protectively involved in the pathogenesis of polyglutamine diseases.
Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA.
Mendelsohn et al., Boston, United States. In J Biol Chem, 2004
M-RIP can assemble a complex containing both RhoA and Myosin phosphatase myosin binding subunit, suggesting that M-RIP may play a role in myosin phosphatase regulation by RhoA
Cryptococcal meningitis in the acquired immunodeficiency syndrome.
Sande et al., San Francisco, United States. In Semin Respir Infect, 1990
Serum cryptococcal antigen (CRAG) is a sensitive test for cryptococcal meningitis, and CSF CRAG is usually also positive.
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