The role of abuse-deterrent formulations in countering opioid misuse and abuse.
Philadelphia, United States. In J Clin Pharm Ther, Dec 2015
A practical way to retain the pain relief afforded by opioids while decreasing opportunities for abuse is to make it more difficult to extract the opioid from the product or to make it less desirable to do so by designing an abuse-deterrent formulation (ADF).
Functions of cofilin in cell locomotion and invasion.
New York City, United States. In Nat Rev Mol Cell Biol, 2013
Recently, a consensus has emerged that cofilin severing activity can generate free actin filament ends that are accessible for F-actin polymerization and depolymerization without changing the rate of G-actin association and dissociation at either filament end.