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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Serine/threonine kinase 35

Clik1, CLP-36 interacting kinase, serine/threonine kinase 35, STK35L1, STK35L, STK35
The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Clp, OUT, Actin, CAN, importin
Papers on Clik1
Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34(+) Cells Deficient in MicroRNA-377.
Krishnamurthy et al., New York City, United States. In J Am Coll Cardiol, Dec 2015
We also validated that serine/threonine kinase 35 is a target of miR-377 using a dual luciferase reporter assay.
Genome-wide linkage and regional association study of blood pressure response to the cold pressor test in Han Chinese: the genetic epidemiology network of salt sensitivity study.
Kelly et al., Beijing, China. In Circ Cardiovasc Genet, 2014
Results of gene-based analyses showed that variants in genes MCM8 and SLC23A2 were associated with systolic BP response to CPT (P=4.0×10(-5) and 2.7×10(-4), respectively), and variants in genes MCM8 and STK35 were associated with mean arterial pressure response to CPT (P=1.5×10(-5) and 5.0×10(-5), respectively).
Nuclear importin α and its physiological importance.
Yoneda et al., In Commun Integr Biol, 2012
With remarkable selectivity, importin α2 can access the promoter of Serine/threonine kinase 35 (STK35) and increase the levels of this transcript without requirement for importin β1.
Nuclear retention of importin α coordinates cell fate through changes in gene expression.
Yoneda et al., Ōsaka, Japan. In Embo J, 2012
constitutive overexpression of STK35 proteins enhances caspase-independent cell death under oxidative stress conditions.
STK35L1 associates with nuclear actin and regulates cell cycle and migration of endothelial cells.
Siess et al., München, Germany. In Plos One, 2010
by regulating CDKN2A and inhibiting G1- to S-phase transition STK35L1 may act as a central kinase linking the cell cycle and migration of endothelial cells
Identifying and characterizing a novel protein kinase STK35L1 and deciphering its orthologs and close-homologs in vertebrates.
Siess et al., München, Germany. In Plos One, 2008
analysis of the STK35L proteins in human and in sea squirts
Diesel exhaust particles disturb gene expression in mouse testis.
Kashiwagura et al., Aomori, Japan. In Environ Toxicol, 2007
On the other hand, the expressions of long-chain acyl-CoA synthetase 6 (Acsl6) and serine/threonine kinase 35 reduced by 0.3-fold.
Molecular cloning and characterization of a novel human kinase gene, PDIK1L.
Mao et al., Shanghai, China. In J Genet, 2003
It encodes a protein of 341 amino acids, which shows 69% identity with the human kinase CLIK1 (AAL99353), which was suggested to be the CLP-36 interacting kinase.
Clik1: a novel kinase targeted to actin stress fibers by the CLP-36 PDZ-LIM protein.
Mäkelä et al., Helsinki, Finland. In J Cell Sci, 2002
results establish the CLP-36 PDZ-LIM protein as an adapter, recruiting the Clik1 kinase to actin stress fibers in nonmuscle cells, and suggest that Clik1 represents a novel regulator of actin stress fibers
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