chemokine-like factor superfamily 8
CMTM8 is Frequently Downregulated in Multiple Solid Tumors.
Beijing, China. In Appl Immunohistochem Mol Morphol, Dec 2015
UNASSIGNED: Previous studies have demonstrated that overexpression of CMTM8 inhibits cell growth and induces apoptosis in multiple types of cancer cells, whereas the downregulation of CMTM8 induces the epithelial-to-mesenchymal (EMT)-like phenotype in hepatocyte carcinoma cells, implying its important roles in tumorigenesis and tumor metastasis.
Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD.
Würzburg, Germany. In Neuropsychopharmacology, 2011
To address these issues, we genotyped SNPs in ANK3, CACNA1C, CMTM8, DGKH, EGFR, and NPAS3, which were significantly associated with BPD in previous GWAS, in a sample of 380 BPD patients.
An alternative splice form of CMTM8 induces apoptosis.
Beijing, China. In Int J Biochem Cell Biol, 2006
The cloning and sequencing of an alternative splice form of CMTM8, obtained from a human blood cDNA library, that utilizes apoptotic pathways distinct from CMTM8, is reported.