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Centrosomal protein 250

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: CAN, FAN, Cdc42, Rhodopsin, HAD
Papers on CEP2
[Prognostic significance of MYCN amplification in children neuroblastic tumors].
Xia et al., Guangzhou, China. In Zhonghua Bing Li Xue Za Zhi, Feb 2015
There were 38 cases (14.2%), 43 cases (16.1%), 71 cases (26.6%), and 115 cases (43.1%) of INSS stages I, II, III and IV respectively.Favorable histology group had 157 cases (59.9%); unfavorable histology group had 110 cases (40.1%).Of the 119 NT cases with MYCN FISH performed, 18 cases (15.1%) showed amplification and the signal ratio of MYCN to CEP2 was 4.08-43.29.
CEP2 attenuates myoblast differentiation but does not affect proliferation.
Mo et al., Guangzhou, China. In Int J Biol Sci, 2014
CEP2 (CDC42EP2) is a member of the CDC42 subfamily that belongs to the Rho family.
Analysis of ALK gene in 133 patients with breast cancer revealed polysomy of chromosome 2 and no ALK amplification.
Nayak et al., New York City, United States. In Springerplus, 2014
FISH was performed using ALK break-apart and chromosome 2 centromere enumeration probes (CEP2).
Comparative evaluation of ethanolic extracts of Bacopa monnieri, Evolvulus alsinoides, Tinospora cordifolia and their combinations on cognitive functions in rats.
Upmanyu et al., Shillong, India. In Curr Aging Sci, 2013
The effects of ethanolic extracts of whole plants of Bacopa monnieri (BME), Evolvulus alsinoides (EAE), Tinospora cordifolia (TCE) and their combinations in equal proportion [CEP-1 (BME+EAE), CEP-2 (BME+TCE), CEP-3 (EAE+TCE) and CEP-4 (BME+EAE+TCE)] were tested in amnesic rats using Radial arm maze task performance (RAM) and Barnes maze test at 200 mg/kg p.o.
Ultrastructure and fertilizing ability of Limousin bull sperm after storage in CEP-2 extender with and without egg yolk.
Pangestu et al., Indonesia. In Pak J Biol Sci, 2012
The aim of this study to evaluate ultrastructure and fertilizing ability of Limousin bull sperm after storage in cauda epididymal plasma-based (CEP-2) extender with or without 20% egg yolk concentration at refrigerator temperature.
Early proliferation alteration and differential gene expression in human periodontal ligament cells subjected to cyclic tensile stress.
Zhao et al., Chengdu, China. In Arch Oral Biol, 2011
CDC42EP2 is upregulated in human PDLCs subjected to tensile stress related to mechano-induced cell cycle arrest.
The antiproliferative effect of dietary fiber phenolic compounds ferulic acid and p-coumaric acid on the cell cycle of Caco-2 cells.
Oredsson et al., Lund, Sweden. In Nutr Cancer, 2010
The expressions of a number of genes involved in centrosome assembly, such as RABGAP1 and CEP2, were upregulated by FA treatment as well as the gene for the S phase checkpoint protein SMC1L1.
Comparative, three-dimensional anterior sensory reconstruction of Aphelenchus avenae (nematoda: Tylenchomorpha).
Baldwin et al., Riverside, United States. In J Comp Neurol, 2010
A higher degree of similarity is shown between A. avenae and A. complexus, with common features including: the presence of a second, internal outer labial dendrite (OL1); a second cephalic dendrite in the female (CEP2/CEM); an accessory process loop of inner labial dendrite 1; and terminus morphology and epidermal associations of internal sensory receptors BAG and URX.
Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation.
Fan et al., Xi'an, China. In Int J Cancer, 2006
activations of Rac1 and Cdc42 are involved in the hypoxia-induced production of angiogenesis-promoting factors and tumor suppressors, and suggest that the Rho family GTPases Rac1 and Cdc42 may contribute to the hypoxia-mediated angiogenesis.
Assemblies of supramolecular porphyrin dimers in pentagonal and hexagonal arrays exhibiting light-harvesting antenna function.
Kobuke et al., Ikoma, Japan. In J Am Chem Soc, 2006
Fluorescence quantum yields of C-EP2 (10.0%),
Comparison of three diluents for the storage of fresh bovine semen.
de Kruif et al., Merelbeke, Belgium. In Theriogenology, 2005
However, a new diluent (CEP-2), which was originally based on the biochemical composition of bovine cauda epididymal plasma, could become an appropriate alternative to Caprogen.
Storage of fresh bovine semen in a diluent based on the ionic composition of cauda epididymal plasma.
de Kruif et al., Merelbeke, Belgium. In Reprod Domest Anim, 2004
Secondly, the ionic composition of the CEP-1 diluent was modified (CEP-2) and its storage capacity was compared with this of the CEP-1 and Tris diluent.
A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes.
Burbelo et al., Washington, D.C., United States. In J Biol Chem, 2001
Experimentally, we have verified that CEP2 and CEP5 bind Cdc42.
INMP, a novel intranuclear matrix protein related to the family of intermediate filament-like proteins: molecular cloning and sequence analysis.
Jost et al., Gie├čen, Germany. In Biochim Biophys Acta, 1996
The cDNA encodes a protein of 446 amino acids named INMP for intranuclear matrix protein.
CEP3 encodes a centromere protein of Saccharomyces cerevisiae.
Koshland et al., Baltimore, United States. In J Cell Biol, 1995
Ten conditional lethal cep mutants were isolated, seven were found to be alleles of NDC10 (CEP2) encoding the 110-kD protein of yeast kinetochore.
The Consortium Ethics Program: an approach to establishing a permanent regional ethics network.
Wicclair et al., Pittsburgh, United States. In Hec Forum, 1995
This paper describes the first three-year experience of the Consortium Ethics Program (CEP-1) of the University of Pittsburgh Center for Medical Ethics, and also outlines plans for the second three-year phase (CEP-2) of this experiment in continuing ethics education.
Rapid method for screening large numbers of Escherichia coli colonies for production of plasmid-mediated beta-lactamases.
McHugh et al., In Antimicrob Agents Chemother, 1983
A rapid, simple assay for screening large numbers of Escherichia coli colonies for production of certain plasmid-mediated beta-lactamases (including TEM-1, TEM-2, HMS-1, SHV-1, OXA-1, PSE-1, PSE-4, and CEP-2) is described.
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