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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Cadherin 22

CDH22, PB cadherin, cadherin-like 22
This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: PRL-3, Prolactin, Otx2, Protocadherin, cadherin-8
Papers on CDH22
High-density genotyping of immune loci in Kawasaki disease and IVIG treatment response in European-American case-parent trio study.
Shrestha et al., Birmingham, United States. In Genes Immun, 2014
We replicated single-nucleotide polymorphisms (SNPs) in three gene regions (FCGR, CD40/CDH22 and HLA-DQB2/HLA-DOB) that have been previously associated with KD and provide support to other findings of several novel SNPs in genes with a potential pathway in KD pathogenesis.
DNA methylation analysis of phenotype specific stratified Indian population.
Satyamoorthy et al., India. In J Transl Med, 2014
Bisulfite DNA sequencing of prakriti specific multiple CpG sites in promoters and 5'-UTR such as; LHX1 (Vata prakriti), SOX11 (Pitta prakriti) and CDH22 (Kapha prakriti) were validated.
Genome-wide association analysis of Sasang constitution in the Korean population.
Kim et al., Taejŏn, South Korea. In J Altern Complement Med, 2012
Fifteen (15) genes, including GPM6A, SYT4, and GRIK1, were significantly associated with the TE constitution type (p<0.05); 12 genes, including DRGX and AKAP11, were significantly associated with the SE constitution type (p<0.05); and 17 genes, including ZFP42, CDH22, ALDH1A2, OTX2, and EN2, were significantly associated with the SY constitution type (p<0.05).
Analysis of Cdh22 expression and function in the developing mouse brain.
Partanen et al., Helsinki, Finland. In Dev Dyn, 2011
Results describe the expression of Cdh22 in developing mouse brain and compare it to expression of related family members.
CDH22 expression is reduced in metastatic melanoma.
Li et al., In Am J Cancer Res, 2010
Cadherin-like protein 22 (CDH22) is a transmembrane glycoprotein implicated in cell-cell adhesion and cancer metastasis.
Expression of two type II cadherins, Cdh12 and Cdh22 in the developing and adult mouse brain.
Lele et al., Budapest, Hungary. In Gene Expr Patterns, 2010
spatio-temporal mRNA distribution pattern of Cdh12 and Cdh22 during CNS development; demonstrate presence of Cdh12 and Cdh22 mRNA in both excitatory and inhibitory neurons in adult CNS including cerebellum, neocortex, hippocampus and subcortical nuclei
PRL-3 promotes epithelial mesenchymal transition by regulating cadherin directly.
Li et al., Guangzhou, China. In Cancer Biol Ther, 2009
PRL-3 promoted downregulation of CDH22 expression.
[Establishment of a colorectal cancer cell line with PRL-3 and CDH22 gene knock-down by lentivirus-mediated RNA interference].
Li et al., Guangzhou, China. In Nan Fang Yi Ke Da Xue Xue Bao, 2009
OBJECTIVE: To establish a colorectal cancer cell line with stable PRL-3 and CDH22 gene knock-down for investigating the role of PRL-3 and CDH22 genes in the carcinogenesis and metastasis of colorectal cancer.
Over-expression of CDH22 is associated with tumor progression in colorectal cancer.
Ding et al., Guangzhou, China. In Tumour Biol, 2008
Our results reveal for the first time a new role of CDH22 in progression of colorectal cancer.
Heterogeneity in gene loci associated with type 2 diabetes on human chromosome 20q13.1.
Mychaleckyj et al., Winston-Salem, United States. In Genomics, 2008
The most significant SNPs were found in the perigenic regions: HNF4A (hepatocyte nuclear factor 4alpha), SLC12A5 (potassium-chloride cotransporter member 5), CDH22 (cadherin-like 22), ELMO2 (engulfment and cell motility 2), SLC13A3 (sodium-dependent dicarboxylate transporter member 3), and PREX1 (phosphatidylinositol 3,4,5-triphosphate-dependent RAC exchanger 1).
[Construction of a lentiviral vector for RNA interference of human CDH22 gene and its gene silencing effect in SW480 cells].
Ding et al., Guangzhou, China. In Nan Fang Yi Ke Da Xue Xue Bao, 2008
OBJECTIVE: To construct a lentiviral expression vector for RNA interference of human CDH22 gene, and assess its gene silencing effect in colorectal cancer cells to provide a basis for investigating the role of CDH22 gene in the signaling pathway involved in human colorectal carcinoma metastasis.
Analysis of the midbrain-hindbrain boundary cell fate using a boundary cell-specific Cre-mouse strain.
Partanen et al., In Genesis, 2008
Initially, the MHB-Cre expression coincides with that of Cdh22 and p21 around the Otx2 expression border in a narrow population of cells with reduced proliferative activity.
Identification and mRNA expression of Ogdh, QP-C, and two predicted genes in the postnatal mouse brain.
Furuichi et al., Wako, Japan. In Neurosci Lett, 2006
By fluorescent differential display, we identified six transcripts (CAPS2/Cadps2, Cdh22, b1402, c1502, d1401, and d1501) that showed the differential expression patterns during the postnatal development of the mouse cerebellum.
Early gene expression changes preceding thyroid hormone-induced involution of a thyrotrope tumor.
Ridgway et al., Denver, United States. In Endocrinology, 2002
These, in addition to two other genes, neuronatin and PB cadherin, which were up- and down-regulated, respectively, showed a more rapid response to TH than the cell cycle regulators and may represent direct targets of TH.
Molecular cloning and characterization of a newly identified member of the cadherin family, PB-cadherin.
Nakamura et al., Ōsaka, Japan. In J Biol Chem, 1996
This paper deals primarily with the rat ortholog of the human CDH22 gene.
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