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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

CD34 molecule

The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: CAN, HAD, CD31, AGE, CD45
Papers using CD34 antibodies
Inhibition of activated receptor tyrosine kinases by Sunitinib induces growth arrest and sensitizes melanoma cells to Bortezomib by blocking Akt pathway
Wang Zhengqi, In PLoS ONE, 2011
... cells were sorted from BMMNCs of patients with AML using the Diamond CD34 Isolation kit (Miltenyi Biotec, Bergisch Gladbach, Germany) according ...
SOCS-3 antagonises the proliferative and migratory effects of FGF-1 2 in prostate cancer by inhibition of p44/p42 MAPK signaling
Oueslati Ridha et al., In Journal of Experimental & Clinical Cancer Research : CR, 2009
... primary antibodies used were: mouse anti-human PSMA (3E6), mouse anti-human PSA (ER-PR8) and mouse anti-human CD34 (QBend10) (Dako, Glostrup, Denmark) ...
A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells.
Covas Dimas, In PLoS ONE, 2008
... fractions was assessed by flow-cytometric analysis with an antibody recognizing a different CD34 epitope (BD Biosciences, San Jose, CA) ...
mRNA-Seq whole-transcriptome analysis of a single cell.
Tjwa Marc, In PLoS ONE, 2008
... hFL CD34+ cells were isolated using EasySep CD34 Selection Kit (StemCell Technologies, Vancouver, Canada) according to ...
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Papers on CD34
Residual disease detected by multidimensional flow cytometry shows prognostic significance in childhood acute myeloid leukemia with intermediate cytogenetics and negative FLT3-ITD: a report from the Tokyo Children's Cancer Study Group.
Ohara et al., Kawasaki, Japan. In Int J Hematol, Feb 2016
RD was evaluated by detecting the immature cells showing abnormal antigen expression pattern; CD34(+), CD15(+), CD7(+).
Distinct routes of lineage development reshape the human blood hierarchy across ontogeny.
Dick et al., Toronto, Canada. In Science, Feb 2016
We developed a cell-sorting scheme to resolve myeloid (My), erythroid (Er), and megakaryocytic (Mk) fates from single CD34(+) cells and then mapped the progenitor hierarchy across human development.
'Papillary' solitary fibrous tumor/hemangiopericytoma with nuclear STAT6 expression and NAB2-STAT6 fusion.
Sasaki et al., Saitama, Japan. In Brain Tumor Pathol, Feb 2016
By immunohistochemistry, CD34 was strongly positive in the tumor cells, and STAT6 was localized in their nuclei.
How to approach the many faces of endometrioid carcinoma.
Malpica, Houston, United States. In Mod Pathol, Jan 2016
Variants with distinct architectural and cytologic features include the following: (1) ECa with a villoglandular pattern (tumor with finger-like papillae lined by bland cells with a tendency for vascular/lymphatic invasion and lymph node metastasis once this pattern is seen within the myoinvasive component); (2) papillary ECa of intermediate grade (grade 2) (tumor that can be mistaken for serous carcinoma, as it contains papillae showing slightly irregular contours, moderately atypical cells, and it is associated with vascular/lymphatic invasion/lymph node metastasis, but with common association with mucinous metaplasia, MELF (microcystic, elongated, and fragmented) pattern of invasion, and wild p53 expression); (3) ECa with non-villous papillae (tumor containing pseudopapillae within glands with bland-appearing cytology commonly associated with abortive squamous differentiation and otherwise not different from usual ECa); (4) ECa with microglandular-like pattern (tumor that mimics microglandular hyperplasia of the cervix, often lacking the typical appearance of microglandular hyperplasia and showing Ki-67 index >10%, strong CD10 expression, and negative PAX-2, p63, and CD34); and (5) ECa with sex cord-like formations and hyalinization (tumor with interconnected cords and nests of bland epithelioid and spindled cells that merge with a typical component of low-grade ECa, usually associated with squamous differentiation and hyalinization).
Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.
Cannon et al., Richmond, United States. In Nat Biotechnol, Dec 2015
Here we report that combining electroporation of zinc finger nuclease (ZFN) mRNA with donor template delivery by adeno-associated virus (AAV) serotype 6 vectors directs efficient genome editing in HSPCs, achieving site-specific insertion of a GFP cassette at the CCR5 and AAVS1 loci in mobilized peripheral blood CD34(+) HSPCs at mean frequencies of 17% and 26%, respectively, and in fetal liver HSPCs at 19% and 43%, respectively.
HMB-45 negative angiomyolipoma of the orbit: a case report and review of the literature.
Liu et al., Taipei, Taiwan. In Bmc Ophthalmol, Dec 2015
Immunohistochemically, tumor cells were positive for CD34 and HHF-35, but negative for cytokeratin, HMB-45 and Melan-A.
Hhex Is Necessary for the Hepatic Differentiation of Mouse ES Cells and Acts via Vegf Signaling.
Bogue et al., New Haven, United States. In Plos One, Dec 2015
Furthermore, we identified VEGFR2+/ALB+/CD34- in early Hhex+/+ hepatic cultures.
Maggot debridement therapy promotes diabetic foot wound healing by up-regulating endothelial cell activity.
Wang et al., Nanjing, China. In J Diabetes Complications, Dec 2015
Moreover, significant elevation in CD34 and CD68 levels was also observed in treated wounds.
HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 Acetylation.
Kuo et al., Duarte, United States. In Cell Stem Cell, Dec 2015
Importantly, HDAC8 inhibition induces apoptosis in inv(16)(+) AML CD34(+) cells, while sparing the normal hematopoietic stem cells.
[Treatment of Gaucher disease with allogeneic hematopoietic stem cell transplantation: report of three cases and review of literatures].
Xu et al., Beijing, China. In Zhonghua Er Ke Za Zhi, Nov 2015
The dose of cord blood stem cell CD34(+) cell counts was 5.4×10(5)/kg , 3.5×10(5)/kg and 3.2×10(5)/kg respectively.
CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.
Cleary et al., Stanford, United States. In Cell Stem Cell, Nov 2015
Although human CD34(+)CD38(-) LSCs are generally highly quiescent, the C-type lectin CD93 is expressed on a subset of actively cycling, non-quiescent AML cells enriched for LSC activity.
Effect of platelet-rich plasma on healing tissues in acute ruptured Achilles tendon: a human immunohistochemistry study.
Franklin et al., Birmingham, United Kingdom. In Lancet, Mar 2015
Immunohistochemistry markers were used to identify collagen I and III, lymphocytes (CD45), proliferation (KI67), and blood vessels (CD34).
Coexistent t(8;21)(q22;q22) Translocation and 5q Deletion in Acute Myeloid Leukemia.
Minami et al., In J Clin Exp Hematop, 2014
Myeloblasts were positive for CD19 and CD56 as well as CD13, CD33, CD34 and HLA-DR.
Saw Palmetto Extract Inhibits Metastasis and Antiangiogenesis through STAT3 Signal Pathway in Glioma Cell.
Che et al., Shenyang, China. In Evid Based Complement Alternat Med, 2014
Meanwhile pSTAT3 is lower in the experimental group and CD34 is also inhibited in the saw palmetto treated group.
Research Note Mesenchymal stem cells from skin lesions of psoriasis patients promote proliferation and inhibit apoptosis of HaCaT cells.
Zhang et al., Taiyuan, China. In Genet Mol Res, 2014
Cell morphologies and multipotencies of skin MSCs were similar between the psoriasis group and healthy control group, with high levels of CD29, CD44, CD73, CD90, and CD105 and limited expression of CD34, CD45, and HLA-DR.
In vitro expanded bone marrow-derived murine (C57Bl/KaLwRij) mesenchymal stem cells can acquire CD34 expression and induce sarcoma formation in vivo.
Van Riet et al., Tianjin, China. In Biochem Biophys Res Commun, 2012
murine in vitro expanded bone marrow-derived murine mesenchymal stem cells can transform into CD34 expressing cells that induce sarcoma formation in vivo.
Sonic hedgehog-modified human CD34+ cells preserve cardiac function after acute myocardial infarction.
Losordo et al., Chicago, United States. In Circ Res, 2012
Sonic hedgehog (Shh)-modified human CD34-positive cells protect against ventricular dilation and cardiac functional decline associated with experimental acute myocardial infarction.
Immunohistochemical study of osteopontin, Ki-67, and CD34 of psoriasis in Mansoura, Egypt.
Azim et al., Al Manşūrah, Egypt. In Indian J Pathol Microbiol, 2012
Osteopontin expression seems to be related to Ki-67 (proliferation index) and CD34 expression (angiogenesis marker) confirming its role in the pathogenesis of psoriasis.
Nestin and caveolin-1 in the diagnosis of GISTs.
Ardeleanu et al., Bucureşti, Romania. In Rom J Morphol Embryol, 2011
nestin and caveolin-1 could have a role in GISTs, together with CD117 and CD34
Mobilization of CD34+CXCR4+ stem/progenitor cells and the parameters of left ventricular function and remodeling in 1-year follow-up of patients with acute myocardial infarction.
Tendera et al., Katowice, Poland. In Mediators Inflamm, 2011
Mobilization of CD34+CXCR4+ cells in acute MI shows significant positive correlation with improvement of LVEF after 1 year
More papers using CD34 antibodies
Role of CD34 antigen in myeloid differentiation of human hematopoietic progenitor cells
Ferrari S et al., In Cell Death & Disease, 2007
... Mononuclear cells were isolated using the EasySep Human Whole Blood/Buffy Coat CD34-Positive Selection Kit (StemCell Technologies, Vancouver, Canada) following the ...
Osteochemonecrosis of the jaws due to bisphosphonate treatments. Update.
Bauer Joseph Alan, In PLoS ONE, 2007
... Primary rat anti-murine CD34 antibody (MEC 14.7) was from Abcam, (Cambridge, MA) ...
Kallikrein-binding protein inhibits growth of gastric carcinoma by reducing vascular endothelial growth factor production and angiogenesis
Guenther T et al., In British Journal of Cancer, 2006
... The antibodies used were for identification of CD34 blood vessels (Novus Biologicals, LLC, Littleton, CO, USA, ...
The pediatric preclinical testing program: description of models and early testing results.
Srivastava Rakesh K., In PLoS ONE, 2006
... Anti-CD34 antibody (ab27448) was from Abcam (Cambridge, MA, USA) ...
Global and Local Architecture of the Mammalian microRNA-Transcription Factor Regulatory Network
Laitala-Leinonen Tiina et al., In Gene Regulation and Systems Biology, 2006
... Cells were incubated for 1 hour with primary antibodies against Sca-1 (1:100), CD45 (1:100) and CD34 (1:400) diluted in DAKO ChemMate Antibody Diluent (Dako, ...
Hemoglobin depletion from red blood cell cytosol reveals new proteins in 2-D gel-based proteomics study
Banerjee S et al., In Cell Death & Disease, 2006
... Purity of the isolated cells was determined using anti-CD34 antibody (BD Biosciences, San Jose, CA, USA) ...
Follicular dendritic cell sarcoma in the lymph nodes of the neck
Adam Patrick et al., In Diagnostic Pathology, 2006
... CD34DAKO ...
Profile of histone lysine methylation across transcribed mammalian chromatin.
Bunting Kevin D., In PLoS ONE, 2005
... cells were then resuspended in PBS and incubated with fluorescent dye conjugated antibodies CD10-APC, CD11b-APC-Cy7, CD34-Pe-Cy7 and CD117-PE (Becton Dickinson, NJ) dead cells were ...
Microvessel density is a prognostic marker of human gastric cancer
Rustin G et al., In British Journal of Cancer, 2005
... CD34 and αSMA double stainingDako's Cytomation Envision double stain system (K5361) (Dako Ltd., Cambridgeshire, UK), was ...
Embryonic stem cell-derived hematopoietic stem cells.
Unutmaz Derya, In PLoS ONE, 2004
... Biotinylated anti-CD34 (RAM34), and IL-7Rα (A7R34) mAbs were purchased from eBioscience (San Diego, CA) ...
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.
Alberola-Ila Jose, In PLoS ONE, 2003
... Antibodies against c-Kit (APC-conjugated, 2B8, eBioscience), Sca-1 (PE-conjugated, D7, eBioscience) and CD34 (Pacific Blue conjugated, RAM34, eBioscience) were also used ...
DAVID: Database for Annotation, Visualization, and Integrated Discovery
Paramio Jesús M. et al., In Stem Cell Reviews, 2002
... Antibodies used were anti-K15 (Neomarkers, Lab Vision, Fremont, CA), anti-CD34 (clone RAM 34, eBioscience, San Diego, CA), anti ...
Prognostic significance of microvessel density and vascular endothelial growth factor (VEGF) expression in non Hodgkin’s lymphomas
Singh Sompal et al., In ISRN Hematology, 2002
... Angiogenesis was assessed using immunohistochemistry for CD34 (Class II, Clone QBEnd 10, DAKO, Denmark) in all the ...
Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis
Rouhi Arefeh et al., In Molecular Cancer, 2002
... cells were stained with allophycoerythrin (APC)-conjugated anti-human CD34 antibody (8G12, Becton Dickinson, San Jose, CA,) and ...
Expression of CC chemokine receptor-7 and regional lymph node metastasis of B16 murine melanoma
Wiesner C et al., In British Journal of Cancer, 2000
... FITC-conjugated anti-CXCR3 mAb and biotinylated goat IgG anti-human CD144 were purchased from R&D Systems, PE-conjugated anti-CD34 from BD Biosciences (San Jose, CA, USA) ...
SOCS proteins: negative regulators of cytokine signaling.
Hartl Dominik, In PLoS ONE, 2000
... 612599, 20 µl per sample), CD34-FITC (BD Biosciences, Cat ...
A role for cell sex in stem cell–mediated skeletal muscle regeneration: female cells have higher muscle regeneration efficiency
Huard Johnny et al., In The Journal of Cell Biology, 2000
... MDSCs were labeled with rat anti–mouse Sca-1 (phycoerythrin) and CD34 (biotin) mAbs (BD Biosciences).
Rapid and simple phenotypic assay for drug susceptibility of human immunodeficiency virus type 1 using CCR5-expressing HeLa/CD4+ cell clone 1–10 (MAGIC-5)
Speck Roberto F., In PLoS ONE, 2000
... HSCs were purified from hCB by using a Direct CD34 Progenitor Cell Isolation Kit and an LS Column (Miltenyi Biotec, Gladbach, Germany) ...
Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31
Brand Marjorie et al., In The EMBO Journal, 2000
... CD34+ cells were enriched through positive immunomagnetic selection using the CD34 MicroBead Kit (Miltenyi Biotec Inc.) (purity >95±3%) and ...
Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor
Nakamura Yukio et al., In Advances in Hematology, 1999
... hematopoietic stem/progenitor cells were collected from human umbilical cord blood using a magnetic cell sorting system, MACS CD34 Isolation kit (Miltenyi Biotec Inc., Sunnyvale, Calif, USA), ...
Sustained Activation of Cell Adhesion Is a Differentially Regulated Process in B Lymphopoiesis
Silberstein Leslie E. et al., In The Journal of Experimental Medicine, 1998
... used for cell staining: FITC-labeled anti-κ light chain, FITC-labeled anti-λ light chain, PE-labeled anti-IgD, PECy5-labeled anti-CD34 (BD Biosciences), and APC-labeled anti-CD19 (Caltag ...
Prox1 function is required for the development of the murine lymphatic system
Maurer Dieter et al., In The Journal of Experimental Medicine, 1998
... FITC-conjugated Abs included anti-CD34 (Becton Dickinson), sheep anti-von Willebrand factor ...
Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin
Gussoni Emanuela et al., In The Journal of Cell Biology, 1998
... cells/ml, and incubated with the following antibodies: anti-human CD34-FITC (BD Biosciences), anti-human CD133-PE (Miltenyi Biotec), ...
CD34+AC133+ cells isolated from cord blood are highly enriched in long-term culture-initiating cells, NOD/SCID-repopulating cells and dendritic cell progenitors
King Michael R et al., In British Journal of Haematology, 1997
... Similarly, separate tubes were prepared with a 2-h incubation of CD34 antibody (100 μg/ml, Santa Cruz Biotechnology, Santa Cruz, CA, USA) ...
Silencing of B Cell Receptor Signals in Human Naive B Cells
Müschen Markus et al., In The Journal of Experimental Medicine, 1996
... Cord blood HSC were isolated using anti-CD34 immunomagnetic beads (Miltenyi Biotec).
Targeted interleukin-2 therapy for spontaneous neuroblastoma metastases to bone marrow
Lesniak Maciej S., In PLoS ONE, 1996
... The purity of hMSC suspensions was assessed by flow cytometry utilizing the following monoclonal antibodies: anti-CD34 fluorescein isothiocyanate (FITC) (BD Biosciences Pharmingen, Franklin Lake, NJ, ...
Gene expression profiles in normal and cancer cells
Brismar K et al., In British Journal of Cancer, 1996
... subunit of IGF-IR (2C8), used for immunohistochemistry, and mouse monoclonal-anti-CD34 (endothelial antigen) were from Santa Cruz Biotechnology, Inc ...
Skeletal, cardiac, and smooth muscle failure in Duchenne muscular dystrophy
Clementi Emilio et al., In Pharmacological Research, 1995
... Fluorescein isothiocyanate-conjugated CD34 antibody was purchased from AbD Serotec (Oxford, UK) and phycoerythrin-conjugated ...
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
Maurer Dieter et al., In The Journal of Experimental Medicine, 1995
... The peridinin chlorophyll protein (PerCP)-conjugated anti-CD34 and anti-CD3 mAbs were from Becton Dickinson, and anti-CD1a CyChrome was ...
An invariant Vα24–JαQ/Vβ11 T cell receptor is expressed in all individual by clonally expanded CD4−8−T cells
Spits Hergen et al., In The Journal of Experimental Medicine, 1993
... mouse anti–human mAbs: phycoerythrin-conjugated (R-PE)–CD4, fluorescein-conjugated FITC–CD3, FITC–CD14, R-PE–CD5, biotin–CD10, R-PE–CD33, biotinylated HLA-DR, and RPE– CD34 (Becton Dickinson ...
Induction of human IgE synthesis in B cells by mast cells and basophils
Banchereau Jacques et al., In The Journal of Experimental Medicine, 1992
... obtained by centrifugation on Ficoll–HyPaque were sequentially labeled with a sterile endotoxin-free murine mAb to CD34 (IOM34; Immunotech, Marseille, France) and with filtered magnetic microbeads (MiniMacs; Miltenyi Biotec, Bergish-Gladbach, Germany) ...
In vitro stimulatory effect of substance P on hematopoiesis.
Rameshwar Pranela et al., In Biological Procedures Online, 1992
... PE-anti-CD34 was purchased from Becton Dickinson, San Jose, CA and ...
Helix-loop-helix proteins as regulators of muscle-specific transcription
Zatz Mayana et al., In Journal of Translational Medicine, 1992
... Firstly, the immunomagnetically selected cells were incubated with the conjugated antibody anti-CD34-PerCP (BD Biosciences), in phosphate-buffered saline (PBS) ...
Interaction of human malignant melanoma (ST-ML-12) tumor spheroids with endothelial cell monolayers. Damage to endothelium by oxygen-derived free radicals.
Gullberg Donald, In PLoS ONE, 1991
... Antibodies for immunostaining were as follows: monoclonal mouse anti-human tenascin, polyclonal rabbit anti-human CD34, polyclonal rabbit anti-human pan-laminin (Abcam, UK), monoclonal mouse anti-human ...
Development of a bone marrow culture for maintenance and growth of normal human B cell precursors.
Unutmaz Derya, In PLoS ONE, 1990
... cells was performed using Direct human CD34 Progenitor Cell Isolation Kit (Miltenyi Biotec, Auburn, CA) ...
Production of human cells expressing individual transferred HLA-A,-B,-C genes using an HLA-A,-B,-C null human cell line
Unutmaz Derya, In PLoS ONE, 1988
... cells were isolated from human CB by using a Direct CD34 Progenitor Cell Isolation Kit and an MS Column (Miltenyi Biotec, Gladbach, Germany) ...
Susceptibility to rheumatoid arthritis maps to a T-cell epitope shared by the HLA-Dw4 DR beta-1 chain and the Epstein-Barr virus glycoprotein gp110.
von Herrath Matthias G., In PLoS ONE, 1988
... HSCs from cord blood using the MACS Direct CD34 Progenitor Cell Isolation Kit (Miltenyi Biotec, Bergisch Gladbach, Germany), their ...
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