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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

CD33 molecule

Top mentioned proteins: CD34, CD13, CAN, HAD, CD14
Papers on CD33
CD33 Expression and Its Association With Gemtuzumab Ozogamicin Response: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531.
Meshinchi et al., Portland, United States. In J Clin Oncol, Feb 2016
PURPOSE: CD33 is variably expressed on acute myeloid leukemia (AML) blasts and is targeted by gemtuzumab ozogamicin (GO).
Antigen-specific immunotherapy for acute myeloid leukemia: where are we now, and where do we go from here?
Walter et al., Saint Louis, United States. In Expert Rev Hematol, Feb 2016
Only the CD33 antibody-drug conjugate gemtuzumab ozogamicin provided benefit in randomized studies.
The influence of myeloid derived suppressor cells on angiogenesis and tumor growth after cancer surgery.
Hong et al., Kunming, China. In Int J Cancer, Feb 2016
Here, we demonstrated that human MDSCs expressing CD11b(+) , CD33(+) and HLA-DR(-) significantly increased in lung cancer patients after thoractomy.
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
Webb et al., Baltimore, United States. In J Immunol, Feb 2016
CD33(+) cells cultured in HNSCC cell line-derived conditioned medium differentiated into myeloid derived suppressor cells (MDSC) (CD33(+)CD11b(+)HLA-DR(-/low)).
Dose-related efficacy and toxicity of gemtuzumab ozogamicin in pediatric acute myeloid leukemia.
Kaspers et al., Amsterdam, Netherlands. In Expert Rev Anticancer Ther, Jan 2016
UNASSIGNED: Gemtuzumab ozogamicin, an anti-tumour antibiotic linked to an anti-CD33 antibody (Mylotarg®), has been well studied in AML in adults but to a lesser extent in children.
Relationship between Alzheimer's disease GWAS-linked top hits and risk of Parkinson's disease with or without cognitive decline: a Chinese population-based study.
Guo et al., Changsha, China. In Neurobiol Aging, Jan 2016
To examine whether there is a genetic link for these diseases, we performed a case-control study in Chinese population to evaluate the association of AD genome-wide association studies top hits with both PD and cognitive function in PD, investigating 13 single-nucleotide polymorphisms in 9 genes (BIN1, CLU, ABCA7, CR1, PICALM, MS4A6A, CD33, MS4A4E, and CD2AP).
Antigen-specific immunotherapies for acute myeloid leukemia.
Walter et al., Seattle, United States. In Hematology Am Soc Hematol Educ Program, Jan 2016
Nonetheless, among the few drugs shown to improve survival in recent randomized trials is the CD33 antibody-drug conjugate gemtuzumab ozogamicin.
[Isolation and Identification of Human Umbilical Cord and Placenta-derived Stem Cells and Their Component Analysis].
Si et al., Dongtai, China. In Zhongguo Shi Yan Xue Ye Xue Za Zhi, Dec 2015
Furthermore, the UPB contained more early precursor of hematopoietic stem cells (CD33(+) CD34(-)) (6.2 ± 13.5) × 10(5), (0.2 ± 0.8) × 10(5) ; and high proportion of MSC to NC (25.21 ± 18.69, 0.05 ± 0.10)%, respectively in 62 samples.
An unusual tumour of the lung.
Sellami-Boudawara et al., In Pathologica, Mar 2015
The neoplastic mast cells stained strongly with tryptase, CD117, CD68 and CD45, CD14 and CD33; whereas the undifferentiated cells lacked all these markers and expressed EMA and cytokeratin.
Polygenic Analysis of Late-Onset Alzheimer's Disease from Mainland China.
Shen et al., Changsha, China. In Plos One, 2014
Finally, we found rs6656401-rs3865444 (CR1-CD33) pairs were significantly associated with decreasing LOAD risk, while rs28834970-rs6656401 (PTK2B-CR1), and rs28834970-rs6656401 (PTK2B-CD33) were associated with increasing LOAD risk.
Coexistent t(8;21)(q22;q22) Translocation and 5q Deletion in Acute Myeloid Leukemia.
Minami et al., In J Clin Exp Hematop, 2014
Myeloblasts were positive for CD19 and CD56 as well as CD13, CD33, CD34 and HLA-DR.
Gemtuzumab ozogamicin in children and adolescents with de novo acute myeloid leukemia improves event-free survival by reducing relapse risk: results from the randomized phase III Children’s Oncology Group trial AAML0531.
Aplenc et al., In J Clin Oncol, 2014
PURPOSE: To improve survival rates in children with acute myeloid leukemia (AML), we evaluated gemtuzumab-ozogamicin (GO), a humanized immunoconjugate targeted against CD33, as an alternative to further chemotherapy dose escalation.
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.
Alzheimer Disease Genetics Consortium et al., New York City, United States. In Jama, 2013
Several loci previously associated with Alzheimer disease but not reaching significance in genome-wide analyses were replicated in gene-based analyses accounting for linkage disequilibrium between markers and correcting for number of tests performed per gene (CR1, BIN1, EPHA1, CD33; 0.0005 < empirical P < .001).
Acute myeloid leukemia in first remission: to choose transplantation or not?
Stone, Boston, United States. In J Clin Oncol, 2013
Bone marrow examination revealed 90% infiltration with myeloid-appearing blasts, and flow cytometry analysis confirmed the diagnosis of acute myeloid leukemia (AML) with expression of CD33, CD13, and CD117.
Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma.
Seeger et al., Los Angeles, United States. In J Clin Oncol, 2012
Expression of genes representing TAMs (CD33/CD16/IL6R/IL10/FCGR3) contributed to 25% of the accuracy of a novel 14-gene tumor classification score.
The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease.
Chen et al., Shanghai, China. In Hum Genet, 2012
data revealed the allele (T) of the rs3865444 polymorphism of the CD33 gene and the allele (C) of the rs610932 polymorphism of the MS4A6A gene may contribute to Alzheimer's disease risk in the Chinese Han population
CD34(+)/CD38(-) stem cells in chronic myeloid leukemia express Siglec-3 (CD33) and are responsive to the CD33-targeting drug gemtuzumab/ozogamicin.
Valent et al., Vienna, Austria. In Haematologica, 2012
CD33 is expressed abundantly on immature CD34(+)/CD38(-) stem cells and may serve as a stem cell target in chronic myeloid leukemia.
Flow cytometric study of potential target antigens (CD19, CD20, CD22, CD33) for antibody-based immunotherapy in acute lymphoblastic leukemia: analysis of 552 cases.
Guarini et al., Roma, Italy. In Leuk Lymphoma, 2011
Studies showed the qualitative and quantitative expression of four target surface antigens, CD19, CD20, CD22, and CD33, for which MoAbs are currently available for clinical use, in ALL.
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
Williams et al., Cardiff, United Kingdom. In Nat Genet, 2011
found independent evidence for association for Alzheimer's disease susceptibility loci at EPHA1, CD33 and CD2AP
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Schellenberg et al., Miami, United States. In Nat Genet, 2011
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
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