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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Activated leukocyte cell adhesion molecule

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011] (from NCBI)
Top mentioned proteins: CD44, endoglin, CAN, CD45, Thy-1
Papers using CD166 antibodies
gplots: Various R programming tools for plotting data.
Rameshwar Pranela, In PLoS ONE, 2009
... conjugated anti-CD105, -CD29, CD14, -CD31, -CD146, -CD44, -CD90 (Dakocytomation, Copenhagen, Denmark); -CD73, -CD34, -CD45, -CD80, -CD86,-CD166, HLA-I (Becton Dickinson Biosciences Pharmingen, San Jose, ...
Epithelial-mesenchymal transition of ovarian tumor cells induces an angiogenic monocyte cell population.
Câmara Niels Olsen Saraiva, In PLoS ONE, 2008
... anti-CD105, -CD146, -CD90 (Miltenyi Biotech, Bergisch Gladbach, Germany); -CD29, -CD44, -CD73, -CD34, -CD45, -CD80, -CD86, -CD166, HLA-I (Becton Dickinson Biosciences Pharmingen, San Jose, ...
Activated leukocyte cell adhesion molecule (ALCAM) is associated with suppression of breast cancer cells invasion
Andersson Yvonne et al., In Cancer Immunology, Immunotherapy, 2005
... The monoclonal IgG anti-ALCAM antibody MAB656 was purchased from RnD Systems (Abingdon, UK) ...
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells.
Bryk Mary, In PLoS ONE, 1990
... Human FLCN siRNA (siFLCN1, Thermo Scientific, J-009998-05-0005); Non-targeting siRNA pool (sc1, Thermo Scientific, D-001810-10-20); Stealth siRNAs targeting ...
Papers on CD166
Phenotypic and genomic analysis of multiple myeloma minimal residual disease tumor cells: a new model to understand chemoresistance.
San Miguel et al., Pamplona, Spain. In Blood, Feb 2016
The MRD subclone showed significant downregulation of genes related to protein processing in endoplasmic reticulum, as well as novel deregulated genes such as ALCAM that is prognostically relevant in MM and may identify chemoresistant PCs in vitro.
Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease.
Lung GO et al., Boston, United States. In Am J Respir Crit Care Med, Feb 2016
Four genes (DNAH8, ALCAM, RARS and GBF1) also demonstrated an increase in rare non-synonymous, stop and/or splice mutations in cases compared to resistant smokers from the COPDGene study; however, these results were not statistically significant.
Dietary Selenium Supplementation Modulates Growth of Brain Metastatic Tumors and Changes the Expression of Adhesion Molecules in Brain Microvessels.
Toborek et al., Miami, United States. In Biol Trace Elem Res, Jan 2016
While administration of tumor cells resulted in a significant upregulation of adhesion molecules in the early stage of tumor progression, overexpression of VCAM-1 (vascular call adhesion molecule-1) and ALCAM (activated leukocyte cell adhesion molecule) messenger RNA (mRNA) was diminished in SeGP65 supplemented mice.
Predominance of Single Prophage Carrying a CRISPR/cas System in "Candidatus Liberibacter asiaticus" Strains in Southern China.
Deng et al., Guangzhou, China. In Plos One, Dec 2015
Within the two currently known prophage types, Type 1 (SC1-like) and Type 2 (SC2-like), A4 genome contained only a Type 2 prophage, CGdP2, namely.
Exposure to Polycyclic Aromatic Hydrocarbons, Plasma Cytokines, and Heart Rate Variability.
Wu et al., Wuhan, China. In Sci Rep, Dec 2015
Additionally, OH-PAHs were positively associated with activated leukocyte cell adhesion molecule (ALCAM) and C-reactive protein (CRP) (p < 0.05), and IQR increases in OH-PAHs were associated with >20% increases in CRP.
Morpho-chemical characterization and surface properties of carcinogenic zeolite fibers.
Ottaviani et al., Urbino, Italy. In J Hazard Mater, Dec 2015
Mineralogical, morphological, chemical, and surface characterizations were performed on two erionites (GF1, MD8) and one offretite (BV12) fibrous samples and, for comparison, one scolecite (SC1) sample.
CD6 as a cell surface receptor and as a target for regulating immune responses.
Brown, Oxford, United Kingdom. In Curr Drug Targets, Sep 2015
UNASSIGNED: CD6 has been exploited as a drug target as its expression is restricted, primarily to T cells, it has a well characterised cell surface ligand, CD166 and regulates T cell activation through a long cytoplasmic tail.
Lesser-Known Molecules in Ovarian Carcinogenesis.
Căruntu et al., Jászvásár, Romania. In Biomed Res Int, 2014
Within this framework, this review presents three protein molecules: ALCAM, c-FLIP, and caveolin, motivated by the perspectives provided through the current limited knowledge on their role in ovarian carcinogenesis and on their potential as prognosis factors.
Chondrogenic induction of mesenchymal stromal/stem cells from Wharton's jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering.
Huselstein et al., Vandœuvre-lès-Nancy, France. In Stem Cell Res Ther, 2014
From day 14 and up to 28 days, the proportion of WJ-MSC CD73(+), CD90(+), CD105(+) and CD166(+) decreased significantly compared to monolayer marker expression.
Biotechnological and biomedical applications of mesenchymal stem cells as a therapeutic system.
Akbarzadeh et al., Tabrīz, Iran. In Artif Cells Nanomed Biotechnol, 2014
MSCs can express surface molecules like CD13, CD29, CD44, CD73, CD90, CD166, CXCL12 and toll-like receptors (TLRs).
Colon cancer: cancer stem cells markers, drug resistance and treatment.
Kucerova et al., Bratislava, Slovakia. In Biomed Pharmacother, 2014
There are several key stem cells markers specified for colon cancer: CD133, CD44, ALDH1, ALCAM.
Stem cells, colorectal cancer and cancer stem cell markers correlations.
Săftoiu et al., Craiova, Romania. In Curr Health Sci J, 2014
Isolation of CR-CSCs can be achieved by targeting and selecting subpopulation of tumor cells based on expression of one or multiple cell surface markers associated with cancer self-renewal, markers as: CD133, CD166, CD44, CD24, beta1 integrin-CD29, Lgr5, EpCAM (ESA), ALDH-1, Msi-1, DCAMLK1 or EphB receptors.
Activated leukocyte cell adhesion molecule (CD166)--its prognostic power for colorectal cancer patients.
Bockhorn et al., Hamburg, Germany. In J Surg Res, 2012
positive prognostic marker for overall survival of colorectal cancer patients
Distinct roles of neuroligin-1 and SynCAM1 in synapse formation and function in primary hippocampal neuronal cultures.
Meriney et al., Pittsburgh, United States. In Neuroscience, 2012
This study presented evidence that combined NL1 and SC1 overexpression triggers excitotoxic neurodegeneration through SC1 signaling at synaptic connections initiated by NL1.
SC1/hevin identifies early white matter injury after ischemia and intracerebral hemorrhage in young and aged rats.
Schlichter et al., Toronto, Canada. In J Neuropathol Exp Neurol, 2012
SC1 appears to characterize damaged striatal white matter damage after multiple types of injury
Activated leukocyte cell-adhesion molecule (ALCAM) promotes malignant phenotypes of malignant mesothelioma.
Sekido et al., Nagoya, Japan. In J Thorac Oncol, 2012
High ALCAM expression is associated with malignant mesothelioma.
Detection of activated leukocyte cell adhesion molecule in the serum of breast cancer patients and implications for prognosis.
Milde-Langosch et al., Hamburg, Germany. In Oncology, 2011
sALCAM levels differed between patients and healthy controls (median 24.2 vs. 18.9 ng/ml, p < 0.001).
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system.
Prat et al., Montréal, Canada. In Nat Immunol, 2008
These findings indicate an important function for ALCAM in the recruitment of leukocytes into the brain.
Cloning from purified high endothelial venule cells of hevin, a close relative of the antiadhesive extracellular matrix protein SPARC.
Springer et al., Boston, United States. In Immunity, 1995
The primary structure and sequence of hevin and similar to SPARC-like proteins from rat and quail, called SC1 or QR1.
Yeast and mammalian ras proteins have conserved biochemical properties.
Scolnick et al., In Nature, 1985
RASsc1 and RASsc2 encode proteins of 309 (SC1) and 322 (SC2) residues which are 62% homologous to mammalian p21 in their 172-amino acid N-terminal sequences.
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