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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Melanoma cell adhesion molecule

CD146, MUC18, MCAM
may act as a cell adhesion molecule; may play a role in tumor growth and invasion [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, CD45, CD34, endoglin, CD31
Papers using CD146 antibodies
Escherichia coli K-1 interaction with human brain micro-vascular endothelial cells triggers phospholipase C-gamma1 activation downstream of phosphatidylinositol 3-kinase.
Jeyaseelan Samithamby, In PLoS ONE, 2002
... (sc-7210), and a rabbit anti-GGT Ab (sc-20638) from Santa Cruz Biotechnology (Santa Cruz, CA); an anti-mouse CD146 Ab FITC-conjugated from Biolegend (San Diego, CA), a rabbit ...
Papers on CD146
Expression of pro-angiogenic genes in mesenchymal stem cells derived from dermis of patients with psoriasis.
Zhang et al., Taiyuan, China. In Int J Dermatol, Feb 2016
Our microarray analysis suggested that the pro-angiogenic genes platelet endothelial cell adhesion molecule-1 (PECAM1), facio-genital dysplasia-5 (FGD5), prostaglandin-endoperoxide synthase-1 (PTGS1), melanoma cell adhesion molecule (MCAM), vasohibin-2 (VASH2), and stabilin-1 (STAB1) are differentially expressed in dermal mesenchymal stem cells in psoriasis.
Use of Anti-Noxa Antibody for Differential Diagnosis between Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia.
Takeshima et al., Hiroshima, Japan. In Pathobiology, Feb 2016
Immunohistochemical staining and statistical analysis of Noxa expression in 81 cases of EM and 55 cases of RMH were performed and compared with the utility of other previously reported antibodies such as Desmin, EMA, GLUT-1, IMP-3 and CD146.
Toll-like Receptor Expression Profile of Human Dental Pulp Stem/Progenitor Cells.
Dörfer et al., Kiel, Germany. In J Endod, Feb 2016
DPSCs were characterized for CD14, CD34, CD45, CD73, CD90, CD105, and CD146 expression and for their multilineage differentiation potential.
Peritoneal malignant mesothelioma (PMM), and primary peritoneal serous carcinoma (PPSC) and reactive mesothelial hyperplasia (RMH) of the peritoneum. Immunohistochemical and fluorescence in situ hybridisation (FISH) analyses.
Hiroshima et al., Tokorozawa, Japan. In J Clin Pathol, Feb 2016
METHODS: To help differentiate PMM from PPSC and RMH, we used immunohistochemistry to examine mesothelial-associated markers (calretinin, AE1/AE3, CK5/6, CAM5.2, D2-40, WT-1, HBME1, thrombomodulin), adenocarcinoma-associated markers (CEA, BerEP4, MOC31, ER (estrogen receptor), PgR, TTF-1, Claudin-4, Pax8), and malignant-related and benign-related markers (epithelial membrane antigen (EMA), desmin, GLUT-1, CD146 and IMP3), and FISH to examine for homozygous deletion of 9p21.
CD146/MCAM defines functionality of human bone marrow stromal stem cell populations.
Kassem et al., Odense, Denmark. In Stem Cell Res Ther, Dec 2015
Thus, we examined the possible use of CD146 to subtype a heterogeneous hMSC population.
Endometrial stem/progenitor cells: the first 10 years.
Deane et al., Australia. In Hum Reprod Update, Dec 2015
Specific markers for their enrichment have been identified, CD146(+)PDGFRβ(+) (platelet-derived growth factor receptor beta) and SUSD2(+) (sushi domain containing-2), which detected their perivascular location and likely pericyte identity in endometrial basalis and functionalis vessels.
Endothelial-binding, proinflammatory T cells identified by MCAM (CD146) expression: Characterization and role in human autoimmune diseases.
McCoy et al., Bethesda, United States. In Autoimmun Rev, May 2015
A subset of T cells defined by the cell surface expression of MCAM (CD146) has been identified in the peripheral circulation of healthy individuals.
Tooth-derived stem cells: Update and perspectives.
Nociti et al., Piracicaba, Brazil. In World J Stem Cells, Apr 2015
Although they present some common markers, such as cluster of differentiation (CD)105, CD146 and STRO-1, SCs derived from various tissues have different patterns in relation to proliferation, clonogenicity, and differentiation abilities in vitro and in vivo.
Concise review: the surface markers and identity of human mesenchymal stem cells.
Leung et al., Hong Kong, Hong Kong. In Stem Cells, 2014
A number of candidate MSC surface markers or markers possibly related to their stemness have been brought forward so far, including Stro-1, SSEA-4, CD271, and CD146, yet there is a large difference in their expression in various sources of MSCs.
Placental site trophoblastic tumor in the pelvic wall: a case report and review of the literature.
Yang et al., Chengdu, China. In Indian J Pathol Microbiol, 2013
Immunohistochemical staining demonstrated that tumor cells were positive for human placental lactogen, CD146, cytokeratin, placental alkaline phosphatase, human chorionic gonadotropin were positive, the Ki-67 proliferative index was about 80%.
Soluble form of the endothelial adhesion molecule CD146 binds preferentially CD16+ monocytes.
Brunelli et al., Genova, Italy. In Mol Biol Rep, 2012
The preferential interaction between soluble CD146 and CD16 positive monocytes may contribute to activation and homing of monocytes into inflamed vascular beds.
Soluble CD146 and APS: a potential biomarker of obstetrical complications?
Bardin et al., Marseille, France. In Lupus, 2012
sCD146 levels are significantly higher in women presenting a history of recurrent fetal losses.
The expression of CD146 predicts a poor overall survival in patients with adenocarcinoma of the lung.
Tanaka et al., Kitakyūshū, Japan. In Anticancer Res, 2012
positive expression of CD146 was associated with a poorer OS according to the survival analysis. CD146 may be a useful marker for predicting poor prognosis in patients with NSCLC following complete resection
CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer.
Yan et al., Beijing, China. In Proc Natl Acad Sci U S A, 2012
CD146 expression was significantly associated with high tumor stage, poor prognosis, and triple-negative breast cancer.
Clinical significance of plasma CD146 and P-selectin in patients with type 2 diabetic nephropathy.
Liu et al., Shanghai, China. In Cytokine, 2012
Expression of CD146 and P-selectin in patients with type 2 diabetes is elevated, and they are positively correlated with severity of diabetic nephropathy.
A perivascular origin for mesenchymal stem cells in multiple human organs.
Péault et al., Pittsburgh, United States. In Cell Stem Cell, 2008
We have prospectively identified perivascular cells, principally pericytes, in multiple human organs including skeletal muscle, pancreas, adipose tissue, and placenta, on CD146, NG2, and PDGF-Rbeta expression and absence of hematopoietic, endothelial, and myogenic cell markers.
Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment.
Bianco et al., Roma, Italy. In Cell, 2007
We show that MCAM/CD146-expressing, subendothelial cells in human BM stroma are capable of transferring, upon transplantation, the HME to heterotopic sites, coincident with the establishment of identical subendothelial cells within a miniature bone organ.
Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.
Jain et al., Boston, United States. In J Clin Oncol, 2006
CD146 is considered a panendothelial-specific marker, but its utility as a CEC marker in cancer patients remains unclear.
Investigation of multipotent postnatal stem cells from human periodontal ligament.
Shi et al., Bethesda, United States. In Lancet, 2004
Findings PDLSCs expressed the mesenchymal stem-cell markers STRO-1 and CD146/MUC18.
Circulating endothelial cells as markers for ANCA-associated small-vessel vasculitis.
Haubitz et al., Hannover, Germany. In Lancet, 2003
Endothelial cells were isolated from peripheral blood by use of Dynabeads coated with antibodies against CD146, and were stained for von Willebrand factor (vWF), CD31, and Ulex Europaeus lectin 1 (UEA-1).
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