Grabbing the genome by the NADs.
Worcester, United States. In Chromosoma, Aug 2015
Recently published studies from several multicellular eukaryotes have begun to reveal the trans-acting factors involved in NAD localization, including the insulator protein CCCTC-binding factor (CTCF), chromatin assembly factor (CAF)-1 subunit p150, several nucleolar proteins, and two long non-coding RNAs (lncRNAs).
Hepatocellular Carcinoma: Basic and Transitional Research.
Shanghai, China. In Gastrointest Tumors, 2014
CSC-based therapies are still in the earlier stages of development and include a neutralizing anti-CD44 antibody, small interfering RNA to suppress epithelial cell adhesion molecular levels, a neutralizing anti-CD13 antibody and a CD13 inhibitor.