GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Calcineurin B
calcineurin B
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Top mentioned proteins:
Cbl, ACID, CNB, CAN, HAD
Papers on
calcineurin B
Genetic and Phenotypic analyses of Calcineurin A subunit in Arthroderma vanbreuseghemii.
New
Chiba, Japan. In Med Mycol, Mar 2016
Calcineurin is a serine/threonine protein phosphatase that consists of catalytic (calcineurin A) and regulatory (calcineurin B) subunits.
Hypercalcaemia in a Patient with 2p13.2-p16.1 Duplication.
New
Sweden. In Horm Res Paediatr, Jan 2016
CONCLUSION: We conclude that partial duplication of 2p can be associated with hypercalcaemia and hypercalciuria and hypothesise that the underlying mechanism is an increased extra-renal, parathyroid hormone-independent 25-hydroxyvitamin D 1α-hydroxylase activity, leading to raised amounts of 1,25-dihydroxyvitamin D. The increased enzymatic activity could possibly be caused by calcineurin B subunit-related macrophage stimulation.
The CBL-Interacting Protein Kinase CIPK23 Regulates HAK5-Mediated High-Affinity K+ Uptake in Arabidopsis Roots.
New
Murcia, Spain. In Plant Physiol, Dec 2015
Expression in a heterologous system showed that the Ca(2+) sensors calcineurin B-like (CBL1), CBL8, CBL9, and CBL10, together with CBL-interacting protein kinase23 (CIPK23), activated HAK5 in vivo.
Dexamethasone promotes hypertrophy of H9C2 cardiomyocytes through calcineurin B pathway, independent of NFAT activation.
New
Chennai, India. In Mol Cell Biochem, Nov 2015
This leads to the activation of calcineurin B, independent of NFAT involvement, which in coordination with ROS induces the activation of JNK of the MAPK signalling.
Calcineurin B stimulates cytokine production through a CD14-independent Toll-like receptor 4 pathway.
New
Beijing, China. In Immunol Cell Biol, Nov 2015
UNASSIGNED: The calcineurin B subunit (CnB) is the regulatory subunit of Cn, a Ca(2+)/calmodulin-dependent serine/threonine protein phosphatase.
The best and the brightest: exploiting tryptophan-sensitized Tb(3+) luminescence to engineer lanthanide-binding tags.
Review
Asheville, United States. In Methods Mol Biol, 2014
The absence of lanthanide ions in living systems means that background signals are generally a nonissue; however, to exploit the advantageous properties it is necessary to engineer a robust lanthanide-binding sequence that can be appended to any macromolecules of interest.
The CBL-CIPK network mediates different signaling pathways in plants.
Review
Dalian, China. In Plant Cell Rep, 2014
The calcineurin B-like protein-CBL-interacting protein kinase (CBL-CIPK) signaling pathway in plants is a Ca²⁺-related pathway that responds strongly to both abiotic and biotic environmental stimuli.
Calcium signaling and biotic defense responses in plants.
Review
Pullman, United States. In Plant Signal Behav, 2013
Alterations in the Ca(2+) concentration are sensed by Ca(2+)-binding proteins, including calmodulin, calcium-dependent protein kinases and calcineurin B-like proteins, which relay or decode the encoded Ca(2+) signals into specific cellular and physiological responses in order to survive challenges by pathogens.
The multiple faces of calcineurin signaling in Caenorhabditis elegans: development, behaviour and aging.
Review
Seattle, United States. In J Biosci, 2013
The C. elegans counterpart of the catalytic subunit, calcineurin A, cna-1/tax-6, and the regulatory subunit, calcineurin B, cnb-1, are known to express ubiquitously in multiple tissues including neurons.
Inside out: targeting NHE1 as an intracellular and extracellular regulator of cancer progression.
Review
Fargo, United States. In Chem Biol Drug Des, 2013
In particular, we will focus on the ezrin, radixin, moesin family proteins, calcineurin B homologous proteins, Ras/Raf/MEK/ERK signaling, and phosphoinositide signaling as they relate to the regulation of sodium hydrogen exchanger isoform one in cancer progression.
Pan-neuronal knockdown of calcineurin reduces sleep in the fruit fly, Drosophila melanogaster.
GeneRIF
Kumamoto, Japan. In J Neurosci, 2011
results indicate a role for Cn and calcium-dependent signal transduction in sleep and memory regulation.
CIB1 is a regulator of pathological cardiac hypertrophy.
Impact
Cincinnati, United States. In Nat Med, 2010
Yeast two-hybrid screening for CIB1-interacting partners identified a related EF hand domain-containing protein, calcineurin B, the regulatory subunit of the prohypertrophic protein phosphatase calcineurin.
A protein kinase, interacting with two calcineurin B-like proteins, regulates K+ transporter AKT1 in Arabidopsis.
Impact
Beijing, China. In Cell, 2006
We demonstrate that CIPK23 directly phosphorylates the K+ transporter AKT1 and further find that CIPK23 is activated by the binding of two calcineurin B-like proteins, CBL1 and CBL9.
The Ca(2+)-calmodulin-activated protein phosphatase calcineurin negatively regulates EGF receptor signaling in Drosophila development.
GeneRIF
Berkeley, United States. In Genetics, 2002
calcineurin, upon activation by Ca(2+)-calmodulin, cooperates with other factors to negatively regulate Egf receptor signaling at the level of sprouty and the GTPase-activating protein Gap1
Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.
Impact
Stanford, United States. In Cell, 2001
Since calcineurin is thought to control nuclear localization of NFATc proteins, we introduced a mutation into the calcineurin B gene that prevents phosphatase activation by Ca(2+) signals.
Calcineurin: form and function.
Review
Impact
Rochester, United States. In Physiol Rev, 2000
It is a heterodimeric protein consisting of a catalytic subunit calcineurin A, which contains an active site dinuclear metal center, and a tightly associated, myristoylated, Ca(2+)-binding subunit, calcineurin B. The primary sequence of both subunits and heterodimeric quaternary structure is highly conserved from yeast to mammals.
A calcium sensor homolog required for plant salt tolerance.
Impact
Tucson, United States. In Science, 1998
SOS3 encodes a protein that shares significant sequence similarity with the calcineurin B subunit from yeast and neuronal calcium sensors from animals.
