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Calcium channel, voltage-dependent, gamma subunit 7

CACNG7, voltage-dependent calcium channel gamma-7 subunit
The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010] (from NCBI)
Top mentioned proteins: WAG, AMH, PAX3, CAN, en-2
Papers on CACNG7
Systematic analysis of gene expression pattern in has-miR-197 over-expressed human uterine leiomyoma cells.
Xu et al., Jiangyin, China. In Biomed Pharmacother, Oct 2015
The qRT-PCR results confirmed that 17 of the 66 selected genes, which were up- or down-regulated more than 10-fold by miR-197, were consistent with the microarray results, including tumorigenesis-related genes, such as DRT7, SLC549, SFMBT2, FLJ37956, FBLN2, C10orf35, HOXD12, CACNG7, and LOC100134279.
Differences among brain tumor stem cell types and fetal neural stem cells in focal regions of histone modifications and DNA methylation, broad regions of modifications, and bivalent promoters.
Bieda et al., Calgary, Canada. In Bmc Genomics, 2013
We verified that a change in a broad modification affected gene expression of CACNG7.
DNA methylation profiling distinguishes histological subtypes of renal cell carcinoma.
Latif et al., Birmingham, United Kingdom. In Epigenetics, 2013
Pathway analysis identified some of the differentially hypermethylated genes to be involved in Wnt (EN2), MAPK (CACNG7) and TGFβ (AMH) signaling, Hippo pathway (NPHP4), and cell death and apoptosis (SPG20, NKX6-2, PAX3 and BAG2).
Molecular remodeling of ion channels, exchangers and pumps in atrial and ventricular myocytes in ischemic cardiomyopathy.
Soldatov et al., Baltimore, United States. In Channels (austin), 2010
(4) In both atrial and ventricular myocytes ischemic cardiomyopathy reduced expression of CACNG7 and induced overexpression of FXYD1, the gene crucial for Na(+) and K(+) homeostasis.
Changes in the proteome of human bronchial epithelial cells following stimulation with leucotriene E4 and transforming growth factor-beta1.
Altraja et al., Tartu, Estonia. In Respirology, 2009
TGF-beta(1) downregulated 18 intracellular proteins, including lamin A/C, glyceraldehyde-3-phosphate dehydrogenase, protein DJ-1, voltage-dependent calcium channel gamma-7 subunit, heterogeneous nuclear ribonucleoprotein A2/B1 and stress-70 protein.
The novel product of a five-exon stargazin-related gene abolishes Ca(V)2.2 calcium channel expression.
Dolphin et al., London, United Kingdom. In Embo J, 2002
Unlike the genes of other potential gamma subunits identified by their homology to the stargazin gene, CACNG7 is a five-, and not four-exon gene whose mRNA encodes a protein we have designated gamma(7).
A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.
Noebels et al., Houston, United States. In Genomics, 2001
In this study, we describe a cluster of three novel gamma subunit genes, CACNG6, CACNG7, and CACNG8, located in a tandem array on 19q13.4.
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