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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Neuronal cell adhesion molecule

Bravo, NrCAM
Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, ACID, CAN, AGE, CaM
Papers using Bravo antibodies
AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity
Rasband Matthew N. et al., In The Journal of Cell Biology, 2006
... NrCAM antibodies were obtained from Abcam.
Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments
Bennett Vann et al., In The Journal of Cell Biology, 1997
... ), NrCAM (Davis et al., 1996) and the peptide CIANHTGVDIHRNGDFQKNG corresponding to residues 1042–1061 of mouse or rat Nav1.6 (Alomone Labs); a goat polyclonal antibody against ...
Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development
Grumet Martin et al., In The Journal of Cell Biology, 1994
... Mouse Nr-CAM cDNA clones, which cover the entire Nr-CAM coding sequence, were cloned from λgt11 mouse embryo library (CLONTECH Laboratories, Inc.), and RNA ...
Papers on Bravo
Evaluation of Gastroesophageal Reflux Disease Using the Bravo Capsule pH System.
Lee et al., Cavite, Philippines. In J Neurogastroenterol Motil, Mar 2016
The Bravo pH wireless system is designed to be user-friendly and has an added advantage of prolonged pH monitoring.
The Role of the Acid Pocket in Gastroesophageal Reflux Disease.
McColl et al., Glasgow, United Kingdom. In J Clin Gastroenterol, Feb 2016
The presence of the acid pocket has been confirmed in other studies using different techniques including high-resolution pHmetry, Bravo capsule, magnetic resonance imaging, and scintigraphy.
Cost-Effectiveness of Ranibizumab Versus Aflibercept for Macular Edema Secondary to Branch Retinal Vein Occlusion: A UK Healthcare Perspective.
Burke et al., Dublin, Ireland. In Adv Ther, Feb 2016
Patient baseline characteristics and efficacy data for ranibizumab were obtained from the BRAVO trial.
Low Esophageal Mucosal Blood Flow in Patients with Nutcracker Esophagus.
Mittal et al., San Diego, United States. In Am J Physiol Gastrointest Liver Physiol, Jan 2016
The EWBP was measured continuously using a custom designed laser Doppler probe tethered to a Bravo capsule, which anchored it to the esophageal wall.
Pre-deployment Heat Acclimatization Guidelines for Disaster Responders.
Brearley, Darwin, Australia. In Prehosp Disaster Med, Jan 2016
The guidelines were implemented for Team Bravo (2nd rotation) of the Australian Medical Assistance Team (AusMAT) deployed to Tacloban, Philippines following Typhoon Haiyan in November 2013.
Stress response of Salmo salar (Linnaeus 1758) facing low abundance infestation of Caligus rogercresseyi (Boxshall & Bravo 2000), an object in the tank, and handling.
Vargas-Chacoff et al., Puerto Montt, Chile. In J Fish Dis, Jan 2016
UNASSIGNED: This study looks at how low infestation loads of adult Caligus rogercresseyi and other stressors affect the physiology of Salmo salar.
Changes in D-dimer and inflammatory biomarkers before ischemic events in patients with peripheral artery disease: The BRAVO Study.
Lloyd Jones et al., Chicago, United States. In Vasc Med, Jan 2016
UNASSIGNED: Whether circulating biomarker levels increase shortly before an ischemic heart disease (IHD) event is unknown.
[New insights on the organization of the nodes of Ranvier].
Devaux, Marseille, France. In Rev Neurol (paris), 2014
The axo-glial contact at nodes implicates adhesion molecules expressed by the Schwann cell (gliomedin and NrCAM), which binds a partner, neurofascin-186, on the axonal side.
Evidence for Association of Cell Adhesion Molecules Pathway and NLGN1 Polymorphisms with Schizophrenia in Chinese Han Population.
Yue et al., Beijing, China. In Plos One, 2014
Moreover, 12 genes (HLA-A, HLA-C, HLA-DOB, HLA-DPB1, HLA-DQA2, HLA-DRB1, MPZ, CD276, NLGN1, NRCAM, CLDN1 and ICAM3) were modestly significantly associated with schizophrenia (P<0.01).
Erratum: Generation of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells.
In J Vis Exp, 2014
The author's name was corrected from: Veronica Rodriquez-Bravo to: Veronica Rodriguez-Bravo.
Laquinimod therapy in multiple sclerosis: a comprehensive review.
Weinstock-Guttman et al., Buffalo, United States. In Neurol Ther, 2014
#NCT00509145) and BRAVO (
Nuclear pores set the speed limit for mitosis.
Hetzer et al., Los Angeles, United States. In Cell, 2014
Rodriguez-Bravo et al.
[From scientific evidence to clinical practice: treatment regimens for macular edema secondary to retinal vein occlusion].
García-Arumí et al., In Arch Soc Esp Oftalmol, 2012
As a result of the BRAVO, CRUISE and GENEVA trials, ranibizumab and the intravitreal biodegradable implants of dexamethasone has recently been approved by the US Food and Drug Administration and the European Medicines Agency for the treatment of RVO secondary edema.
[BRAVO and CRUISE: ranibizumab for the treatment of macular edema secondary to retinal vein occlusion].
Ruiz Moreno et al., In Arch Soc Esp Oftalmol, 2012
This article summarizes the results of the BRAVO and CRUISE trials, two randomized multicenter studies in patients with macular edema secondary to branch and central retinal vein occlusion, respectively.
Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.
Mason et al., New York City, United States. In Neuron, 2012
These findings suggest a mechanism by which a complex of Sema6D, Nr-CAM, and Plexin-A1 at the chiasm midline alters the sign of Sema6D and signals Nr-CAM/Plexin-A1 receptors on retinal ganglion cells to implement the contralateral retinal cell projection.
The role of NrCAM in neural development and disorders--beyond a simple glue in the brain.
Sakurai, Kyoto, Japan. In Mol Cell Neurosci, 2012
mechanisms of NrCAM participation in development and how these might be perturbed in disorders are reviewed. [review]
Overexpression of neurone glial-related cell adhesion molecule is an independent predictor of poor prognosis in advanced colorectal cancer.
Salto-Tellez et al., Singapore, Singapore. In Cancer Sci, 2011
Nr-CAM protein expression is upregulated in colorectal cancer tissues; Nr-CAM overexpression is an independent marker of poor prognosis among advanced CRC patients, and a possible predictive marker for non-beneficence to 5-fluorouracil-based chemotherapy
NrCAM deletion causes topographic mistargeting of thalamocortical axons to the visual cortex and disrupts visual acuity.
Maness et al., Chapel Hill, United States. In J Neurosci, 2011
NrCAM is required for normal maturation of cortical visual acuity. The aberrant projection of thalamic motor and somatosensory axons to the visual cortex in NrCAM-null mutant mice impairs cortical functions.
A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier.
Peles et al., Israel. In Neuron, 2010
Here, we show that initial clustering of Na(+) channels at heminodes requires glial NrCAM and gliomedin, as well as their axonal receptor neurofascin 186 (NF186).
Thyroid neoplasia in Marshall Islanders exposed to nuclear fallout.
LoGerfo et al., In Jama, 1987
We studied the risk of thyroid neoplasia in Marshall Islanders exposed to radioiodines in nuclear fallout from the 1954 BRAVO thermonuclear test.
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