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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Brain-derived neurotrophic factor

Brain-derived neurotrophic factor, BDNF
Top mentioned proteins: TrkB, CAN, V1a, AGE, HAD
Papers using Brain-derived neurotrophic factor antibodies
Identification of prothymosin-α1, the necrosis–apoptosis switch molecule in cortical neuronal cultures
Ueda Mutsumi et al., In The Journal of Cell Biology, 2005
... The antibodies used in the present study were GULT1 and -4; BDNF; phosphorylated PKCα, -βI, -βII, -γ, -ɛ, and -δ (all from Santa Cruz Biotechnology, Inc.); activated caspase-3 and ...
The effects of acute and long-term lithium treatments on trkB neurotrophin receptor activation in the mouse hippocampus and anterior cingulate cortex.
Gaetani Silvana, In PLoS ONE, 2005
... Chao, Skirball Institute, NY, USA), sc-11-R (1∶2000, Santa Cruz Biotechnology), anti-TrkB (1∶2000, BD Biosciences) or anti-BDNF (N-20/sc-546, Santa Cruz Biotechnology).
Exercise differentially regulates synaptic proteins associated to the function of BDNF
Czarkowska-Bauch Julita et al., In BMC Neuroscience, 2005
... The primary polyclonal antibody against BDNF (N-20; sc-546) and the respective control peptide (N20P 546) were purchased from Santa Cruz Biotechnology, Inc ...
Carnitine protects the molecular chaperone activity of lens a-crystallin and decreases the post-translational protein modifications induced by oxidative stress.
Abraham Edathara, In PLoS ONE, 2000
... 4 h and then incubated for 10 min in the absence or in the presence of BDNF (Alomone Labs, Jerusalem, Israel) at a final ...
Up-regulation of Bcl-xL in response to subtoxic beta-amyloid: role in neuronal resistance against apoptotic and oxidative injury
Ojala Johanna O et al., In Journal of Neuroinflammation, 2000
... MO, USA) treatment, which was followed by 4 days of 50 ng/mL human recombinant brain-derived neurotrophic factor (BDNF; Alomone Labs, Jerusalem, Israel) treatment in ...
Papers on Brain-derived neurotrophic factor
Changes of synapses in experimental autoimmune encephalomyelitis by using Fasudil.
Xiao et al., Datong, China. In Wound Repair Regen, Feb 2016
Neurotrophic factor BDNF and GDNF as well as immunomodulatory cytokine IL-10 in spinal cord were elevated in Fasudil-treated mice, while inflammatory cytokine IL-17, IL-1β, IL-6 and TNF-⟨ were obviously inhibited, accompanied by the decrease of inflammatory M1 iNOS and the increase of anti-inflammatory M2 Arg-1, providing a microenvironment that contributes to synaptic protection.
Baclofen prevents the elevated plus maze behaviour and bdnf expression during naloxone precipitated morphine withdrawal in male and female mice.
Balerio et al., Junín, Argentina. In Synapse, Feb 2016
There are no previous reports regarding sex differences in the elevated plus maze (EPM) and the expression of BDNF in morphine-withdrawn mice.
Brain-derived neurotrophic factor (BDNF) - TrkB signaling in inflammation-related depression and potential therapeutic targets.
Hashimoto et al., Chiba, Japan. In Curr Neuropharmacol, Feb 2016
Signaling via brain-derived neurotrophic factor (BDNF) and its receptor, tropomycin receptor kinase B (TrkB) plays a key role in the pathophysiology of depression and in the therapeutic mechanisms of antidepressants.
Neuropathological relationship between major depression and dementia: A hypothetical model and review.
Lafer et al., Toronto, Canada. In Prog Neuropsychopharmacol Biol Psychiatry, Feb 2016
This may be due to decreased neurogenesis from lower levels of brain-derived neurotrophic factor (BDNF), excitotoxicity from increased glutamate signaling, and lower levels of gamma-aminobutyric acid (GABA) signaling.
Nudging Oligodendrocyte Intrinsic Signaling to Remyelinate and Repair: Estrogen Receptor Ligand Effects.
Tiwari-Woodruff et al., Riverside, United States. In J Steroid Biochem Mol Biol, Feb 2016
Indeed, therapeutic treatment of EAE mice with various ERβ agonists results in increased brain-derived neurotrophic factor (BDNF) and phosphorylated (p) Akt and p-mTOR levels.
Neurobiological actions by three distinct subtypes of brain-derived neurotrophic factor: Multi-ligand model of growth factor signaling.
Kojima et al., Ōsaka, Japan. In Pharmacol Res, Jan 2016
UNASSIGNED: Brain-derived neurotrophic factor (BDNF) is one of the most active members of the neurotrophin family.
Brain-derived neurotrophic factor and its clinical implications.
Das et al., Vishākhapatnam, India. In Arch Med Sci, Jan 2016
Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity, which is essential for learning and memory.
7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders.
Ye et al., Wuhan, China. In Transl Neurodegener, Dec 2015
Brain-derived neurotrophic factor (BDNF) regulates a variety of biological processes predominantly via binding to the transmembrane receptor tyrosine kinase TrkB.
Functional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon Transport.
Rissman et al., San Diego, United States. In Plos One, Dec 2015
Furthermore, while both acute and chronic CRF treatment led to significant reduction in CREB activation and axon transport of brain-derived neurotrophic factor (BDNF), this was not the case with mitochondrial transport.
Connections of the Mouse Orbitofrontal Cortex and Regulation of Goal-Directed Action Selection by Brain-Derived Neurotrophic Factor.
Gourley et al., Atlanta, United States. In Biol Psychiatry, Dec 2015
In particular, we knocked down brain-derived neurotrophic factor (Bdnf) bilaterally in the OFC or generated an OFC-amygdala "disconnection" by pairing unilateral OFC Bdnf knockdown with lesions of the contralateral amygdala.
HMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice.
Pahan et al., Chicago, United States. In Cell Metab, Sep 2015
Accordingly, simvastatin increases CREB and brain-derived neurotrophic factor (BDNF) in the hippocampus of Ppara null mice receiving full-length lentiviral PPARα, but not L331M/Y334D statin-binding domain-mutated lentiviral PPARα.
Discrete BDNF Neurons in the Paraventricular Hypothalamus Control Feeding and Energy Expenditure.
Xu et al., Jupiter, United States. In Cell Metab, Aug 2015
Brain-derived neurotrophic factor (BDNF) is a key regulator of energy balance; however, its underlying mechanism remains unknown.
Elucidating molecular phenotypes caused by the SORL1 Alzheimer's disease genetic risk factor using human induced pluripotent stem cells.
Goldstein et al., San Diego, United States. In Cell Stem Cell, May 2015
We found that human neurons carrying SORL1 variants associated with an increased SAD risk show a reduced response to treatment with BDNF, at the level of both SORL1 expression and APP processing.
The paraventricular thalamus controls a central amygdala fear circuit.
Li et al., New York City, United States. In Nature, Apr 2015
Notably, PVT modulation of SOM(+) CeL neurons was mediated by activation of the brain-derived neurotrophic factor (BDNF) receptor tropomysin-related kinase B (TrkB).
The cellular and molecular basis of direction selectivity of Aδ-LTMRs.
Ginty et al., Baltimore, United States. In Cell, 2015
The neurotrophic factor BDNF is synthesized in epithelial cells on the caudal, but not rostral, side of hair follicles, in close proximity to Aδ-LTMR lanceolate endings, which express TrkB.
Activity-dependent transcription of BDNF enhances visual acuity during development.
Ruthazer et al., Montréal, Canada. In Neuron, 2011
These results indicate that brief sensory stimulation, by initiating nuclear transcription and de novo protein synthesis of BDNF, can facilitate the refinement of response properties in the developing visual system.
Bidirectional remodeling of β1-integrin adhesions during chemotropic regulation of nerve growth.
Henley et al., Rochester, United States. In Bmc Biol, 2010
Findings demonstrate the neurotrophin, BDNF-dependent formation of integrin beta1-based adhesions in the growth cone and reveal how a positive regulator of substrate adhesions can block the negative remodeling and growth inhibitory effects of myelin-associated glycoprotein .
Differential neuroendocrine expression of multiple brain-derived neurotrophic factor transcripts.
Jenks et al., Nijmegen, Netherlands. In Endocrinology, 2009
The upstream open reading frames of BDNF transcripts I and IV markedly decrease BDNF translation efficiency, giving the first indication for a functional role of untranslated BDNF exons.
Pituitary adenylate cyclase-activating polypeptide regulates brain-derived neurotrophic factor exon IV expression through the VPAC1 receptor in the amphibian melanotrope cell.
Jenks et al., Nijmegen, Netherlands. In Endocrinology, 2008
PACAP stimulates the expression of BDNF transcript IV.
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