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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Bone morphogenetic protein 1

Bone morphogenetic protein, BMP-1, procollagen C-proteinase, bone morphogenetic protein-1
This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008] (from NCBI)
Top mentioned proteins: CAN, BMP4, V1a, HAD, Smad1
Papers on Bone morphogenetic protein
Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2.
Soo et al., Los Angeles, United States. In Am J Pathol, Feb 2016
Bone morphogenetic protein (BMP)-2 is used clinically for skeletal repair, but in vivo administration can induce abnormal, adipose-filled, poor-quality bone.
Pax8 plays a pivotal role in regulation of cardiomyocyte growth and senescence.
Geng et al., Wenzhou, China. In J Cell Mol Med, Feb 2016
Bone morphogenetic protein receptor IA (ALK3) mediates the development of ventricular septal defect (VSD).
BMP Sustains Embryonic Stem Cell Self-Renewal through Distinct Functions of Different Krüppel-like Factors.
Miyazono et al., Uppsala, Sweden. In Stem Cell Reports, Feb 2016
Bone morphogenetic protein (BMP) signaling exerts paradoxical roles in pluripotent stem cells (PSCs); it sustains self-renewal of mouse embryonic stem cells (ESCs), while it induces differentiation in other PSCs, including human ESCs.
Altered Expression of Bone Morphogenetic Protein Accessory Proteins in Murine and Human Pulmonary Fibrosis.
McLoughlin et al., Dublin, Ireland. In Am J Pathol, Feb 2016
The balance between transforming growth factor β1 and bone morphogenetic protein (BMP) signaling plays an important role in tissue homeostasis, and alterations can result in pulmonary fibrosis.
Bone morphogenetic protein-2 and bone therapy: successes and pitfalls.
Dass et al., Australia. In J Pharm Pharmacol, Feb 2016
OBJECTIVES: Bone morphogenetic proteins (BMPs), more specifically BMP-2, are being increasingly used in orthopaedic surgery due to advanced research into osteoinductive factors that may enhance and improve bone therapy.
Tuning cellular responses to BMP-2 with material surfaces.
Cavalcanti-Adam et al., Stuttgart, Germany. In Cytokine Growth Factor Rev, Jan 2016
UNASSIGNED: Bone morphogenetic protein 2 (BMP-2) has been known for decades as a strong osteoinductive factor and for clinical applications is combined solely with collagen as carrier material.
Systematic Review and Meta-Analysis of Recombinant Human Bone Morphogenetic Protein-2 in Localized Alveolar Ridge and Maxillary Sinus Augmentation.
Anderson et al., Madison, United States. In J Oral Maxillofac Surg, Dec 2015
PURPOSE: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is approved by the Food and Drug Administration as a viable alternative to bone graft in spinal fusion and maxillary sinus lift.
BMP-1 participates in the selection and dominance of buffalo follicles by regulating the proliferation and apoptosis of granulosa cells.
Shi et al., Nanning, China. In Theriogenology, Dec 2015
UNASSIGNED: BMP1/TLD-related metalloproteinases play a key role in morphogenesis via the proteolytic maturation of a number of extracellular matrix proteins and the activation of a subset of growth factors of the transforming growth factor beta superfamily.
Extracellular signaling molecules to promote fracture healing and bone regeneration.
Shaughnessy et al., East Lansing, United States. In Adv Drug Deliv Rev, Dec 2015
The first commercialized growth factors approved for bone regeneration, Bone Morphogenetic Protein 2 and 7 (BMP2 and BMP7), are direct inducers of osteoblast differentiation.
An emerging role for prdm family genes in dorsoventral patterning of the vertebrate nervous system.
Sagerström et al., Worcester, United States. In Neural Dev, 2014
This DV pattern is initiated by two morphogens-Sonic Hedgehog released from notochord and floor plate and Bone Morphogenetic Protein produced in the roof plate-that act in concentration gradients to induce expression of genes along the DV axis.
Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish.
Carney et al., Singapore, Singapore. In Am J Hum Genet, 2012
The molecular and cellular bases of BMP1-dependent osteogenesis were defined. The importance of BMP1 for bone formation and stability were shown in humans and zebrafish.
Identification of a mutation causing deficient BMP1/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta.
Ruiz-Perez et al., Madrid, Spain. In Hum Mutat, 2012
We conclude that BMP1 is an additional gene mutated in autosomal recessive osteogenesis imperfecta (AR-OI).
High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival.
Foreman et al., Aurora, United States. In Neuro Oncol, 2011
High expression of BMP pathway genes are associated with atypical teratoid/rhabdoid tumors.
Does bone morphogenetic protein increase the incidence of perioperative complications in spinal fusion? A comparison of 55,862 cases of spinal fusion with and without bone morphogenetic protein.
Scoliosis Research Society Morbidity and Mortality Committee et al., Charlottesville, United States. In Spine (phila Pa 1976), 2011
Excluding anterior cervical fusions, there are no significant differences between spinal fusion procedures with and without BMP-associated overall complications.
Bone morphogenetic protein-1 processes insulin-like growth factor-binding protein 3.
Greenspan et al., Madison, United States. In J Biol Chem, 2011
Bone morphogenetic protein-1 processes insulin-like growth factor-binding protein 3.
Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis.
Mullins et al., Philadelphia, United States. In Nat Cell Biol, 2009
Patterning the embryonic dorsoventral axis of both vertebrates and invertebrates requires signalling through bone morphogenetic proteins (BMPs).
Robust stability of the embryonic axial pattern requires a secreted scaffold for chordin degradation.
Sasai et al., Kōbe, Japan. In Cell, 2008
ONT1 binds Chordin and BMP1/Tolloid-class proteinases (B1TP) via distinct domains and acts as a secreted scaffold that enhances B1TP-mediated Chordin degradation by facilitating enzyme-substrate association.
Residual disease monitoring in childhood acute myeloid leukemia by multiparameter flow cytometry: the MRD-AML-BFM Study Group.
Reinhardt et al., Hannover, Germany. In J Clin Oncol, 2006
In a multivariate analysis, using a combined risk classification based on morphologically determined blasts at BMP1 and BMP2, French-American-British classification, and cytogenetics, the influence of immunologically determined RD was no longer statistically significant.
Sizzled controls dorso-ventral polarity by repressing cleavage of the Chordin protein.
Hibi et al., Kōbe, Japan. In Nat Cell Biol, 2006
The Bone morphogenetic protein (Bmp) signalling gradient has a major function in the formation of the dorso-ventral axis.
Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases.
De Robertis et al., Los Angeles, United States. In Cell, 2006
Sizzled is also a natural inhibitor of BMP1, a Tolloid metalloproteinase of medical interest.
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