GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
BDKRB1 bradykinin receptor B1
BDKRB1, bradykinin receptor B1
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Top mentioned proteins:
bradykinin receptor, HAD, B2 receptor, ACID, Kallikrein
Papers on
BDKRB1
Analgesic and anti-inflammatory effects of UP1304, a botanical composite containing standardized extracts of Curcuma longa and Morus alba.
New
Seattle, United States. In J Integr Med, Jan 2016
CONCLUSION: Data presented here suggest that UP1304, analgesic and anti-inflammatory agent of botanical origin, acted as a bradykinin receptor B1 and B2 antagonist, and inhibited COX and LOX enzyme activities.
Association of the bradykinin receptors genes variants with hypertension: a case-control study and meta-analysis.
New
Beijing, China. In Clin Exp Hypertens, Jan 2016
For the case-control study, we identified the genotypes of -58T/C and 1098A/G polymorphism in BDKRB2 and BDKRB1 genes, respectively, by TaqMan PCR method.
The landscape of copy number variations in Finnish families with autism spectrum disorders.
New
Helsinki, Finland. In Autism Res, Jul 2015
Additionally, several novel candidate genes (BDKRB1, BDKRB2, AP2M1, SPTA1, PTH1R, CYP2E1, PLCD3, F2RL1, UQCRC2, LILRB3, RPS9, and COL11A2) were identified through gene prioritization.
Pharmacogenetic Risk Stratification in Angiotensin-Converting Enzyme Inhibitor-Treated Patients with Congestive Heart Failure: A Retrospective Cohort Study.
Denmark. In Plos One, 2014
Score A combined single nucleotide polymorphisms (SNPs) of the angiotensin II receptor type 1 gene (rs275651 and rs5182) and the bradykinin receptor B1 gene (rs12050217).
Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation.
Würzburg, Germany. In J Cereb Blood Flow Metab, 2012
The two bradykinin receptors B1R and B2R are central components of the kallikrein-kinin system with different expression kinetics and binding characteristics.
Genome-wide analysis of pain-, nerve- and neurotrophin -related gene expression in the degenerating human annulus.
Charlotte, United States. In Mol Pain, 2011
Analyses of more degenerated vs. less degenerated discs identified significant upregulation of well-recognized pain-related genes (bradykinin receptor B1, calcitonin gene-related peptide and catechol-0-methyltransferase).
Pharmacogenetics of new analgesics.
Review
Frankfurt am Main, Germany. In Br J Pharmacol, 2011
Among G protein coupled receptors, δ-opioid receptors (coded by OPRD1), cannabinoid receptors (CNR1 and CNR2), metabotropic glutamate receptors (mGluR5 coded by GRM5), bradykinin B(1) (BDKRB1) and 5-HT(1A) (HTR1A) receptors are targeted by new analgesic substances.
Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis.
Montréal, Canada. In Arthritis Res Ther, 2010
Along with the inflammatory nonapeptide vasodilator bradykinin (BK), which acts via bradykinin receptor B1 (BKB1) in chronic inflammatory conditions, these vasoactive factors potentiate joint pain and inflammation.
Effects of the demethylating agent, 5-azacytidine, on expression of the kallikrein-kinin genes in carcinoma cells of the lung and pleura.
Perth, Australia. In Patholog Res Int, 2010
Tissue kallikrein (KLK1) and plasma kallikrein (KLKB1) may regulate the growth and proliferation of tumours of the lung and pleura, through the generation of kinin peptides that signal through the kinin B(1) (BDKRB1) and B(2) (BDKRB2) receptors.
Genomic phenotype of non-cultured pulmonary fibroblasts in idiopathic pulmonary fibrosis.
Manassas, United States. In Genomics, 2010
Specifically, FBXO32, CXCL14, BDKRB1 and NMNAT1 were up-regulated, while RARA and CDKN2D were down-regulated.
Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation.
Würzburg, Germany. In J Cereb Blood Flow Metab, 2010
Kinins are proinflammatory and vasoactive peptides that are released during tissue damage and may contribute to neuronal degeneration, inflammation, and edema formation after brain injury by acting on discrete bradykinin receptors, B1R and B2R.
Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema.
Würzburg, Germany. In Stroke, 2009
BACKGROUND AND PURPOSE: Brain edema is detrimental in ischemic stroke and its treatment options are limited.
Study of candidate genes affecting the progression of renal disease in autosomal dominant polycystic kidney disease type 1.
Barcelona, Spain. In Nephrol Dial Transplant, 2007
The candidate genes (and polymorphisms) studied were the following: NOS3 (T-786C and E298D), BDKRB1 (-699 G > C), BDKRB2 (R14C), TGFB1 (-509 C > T, R25P and L10P), ACE (I/D), EGFR (IVS1CA) and PKD2 (-9780 G > A, -718 A > G and 83 C > G).
Identification of the critical residues of bradykinin receptor B1 for interaction with the kinins guided by site-directed mutagenesis and molecular modeling.
Rahway, United States. In Biochemistry, 2007
We report the critical residues for the interaction of the kinins with human bradykinin receptor 1 (B1) using site-directed mutagenesis in conjunction with molecular modeling of the binding modes of the kinins in the homology model of the B1 receptor.
Molecular identification and pharmacological profile of the bovine kinin B1 receptor.
GeneRIF
Québec, Canada. In Biol Chem, 2006
kinin B1 receptor (B1R) gene ortholog(BDKRB1)was confirmed; putative Zn2+-binding motif HEXXH is not present (replaced by HDAWP); receptor binds [3H]Lys-des-Arg9-bradykinin (K(d) 0.36 nM) and exhibits a pharmacological profile like human B(1)R
Regulation of the kinin receptors after induction of myocardial infarction: a mini-review.
Review
Berlin, Germany. In Braz J Med Biol Res, 2000
It is well known that the responses to vasoactive kinin peptides are mediated through the activation of two receptors termed bradykinin receptor B1 (B1R) and B2 (B2R).
