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Acyl-CoA thioesterase 7

This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, ACID, AGE, HAD, fibrillin-1
Papers on Bach
Pharmacogenetics of isoniazid-induced hepatotoxicity.
Wilffert et al., Yogyakarta, Indonesia. In Drug Metab Rev, May 2015
Some studies of human leukocyte antigen (HLA), Uridine 5'-dipphospho (UDP) glucuronosyltransferase (UGT), nitric oxide synthase (NOS), Broad complex, Tramtrack, Bric-a-brac (BTB) and cap'n'collar type of basic region leucine zipper factor family (CNC) homolog (BACH) and Maf basic leucine zipper protein (MAFK) polymorphisms showed their roles in isoniazid-induced hepatotoxicity by modifying the expression of antioxidant enzymes.
Native fold and docking pose discrimination by the same residue-based scoring function.
Laio et al., Trieste, Italy. In Proteins, Apr 2015
Here, we describe BACH-SixthSense, a single residue-based statistical potential that can be successfully employed in both contexts.
Bach Is the Father of Harmony: Revealed by a 1/f Fluctuation Analysis across Musical Genres.
Yao et al., Beijing, China. In Plos One, 2014
Harmony is a fundamental attribute of music.
Intra- and inter-population polymorphism in Coletinia maggii (Grassi, 1887) (Zygentoma: Nicoletiidae), an inhabitant of soil, mesovoid shallow substratum (MSS) and caves-A challenge for the strict classification of subterranean fauna?
Ortuño et al., Madrid, Spain. In Zootaxa, 2014
Based on the results, Coletinia hernandoi Molero, Bach & Gaju, 2013 is proposed as a new synonym of C. maggii.
Novel biomarkers in acute heart failure: MR-pro-adrenomedullin.
Peacock, In Clin Chem Lab Med, 2014
The prognostic potential of MR-proADM was recently demonstrated in the Biomarkers in Acute Heart Failure (BACH) trial.
Baseline and storm event monitoring of Bacteroidales marker concentrations and enteric pathogen presence in a rural Canadian watershed.
Bezanson et al., Halifax, Canada. In Water Res, 2014
However, the human associated marker (BacH) was only detected once in spite of numerous on-site residential wastewater treatment systems in the watershed, suggesting that this assay is not sensitive enough to detect this type of human sewage source.
Matrix-assisted laser desorption/ionization tandem mass spectrometry of N-glycans derivatized with isonicotinic hydrazide and its biotinylated form.
Kapková et al., Würzburg, Germany. In Rapid Commun Mass Spectrom, 2014
METHODS: Glycans, released from ribonuclease B and ovalbumin, were derivatized with hydrazine labels (isoniazid (INH), biotinylated isonicotinic hydrazide (BINH) and biotinamidocaproylhydrazide (BACH)).
A novel CXCR3-B chemokine receptor-induced growth-inhibitory signal in cancer cells is mediated through the regulation of Bach-1 protein and Nrf2 protein nuclear translocation.
Pal et al., Boston, United States. In J Biol Chem, 2014
There was an increased nuclear localization of Bach-1 and nuclear export of Nrf2, which are important negative and positive transcription factors, respectively, for HO-1 expression.
Sleep related problems and urological symptoms: testing the hypothesis of bidirectionality in a longitudinal, population based study.
Bliwise et al., Boston, United Kingdom. In J Urol, 2014
MATERIALS AND METHODS: Data were obtained from a prospective cohort study of 1,610 men and 2,535 women who completed baseline (2002 to 2005) and followup (2006 to 2010) phases of the BACH (Boston Area Community Health) Survey, a population based random sample survey.
The integrative role of the sigh in psychology, physiology, pathology, and neurobiology.
Ramirez, Seattle, United States. In Prog Brain Res, 2013
"Sighs, tears, grief, distress" expresses Johann Sebastian Bach in a musical example for the relationship between sighs and deep emotions.
Wearing red for signaling: the heme-bach axis in heme metabolism, oxidative stress response and iron immunology.
Watanabe-Matsui et al., In Tohoku J Exp Med, 2013
We discuss future issues regarding the topic of the iron/heme-gene regulation network based on current understanding of the heme-Bach axis, including the concept of "iron immunology" as the synthesis of the iron metabolism and the immune response.
Hepatic HMOX1 expression positively correlates with Bach-1 and miR-122 in patients with HCV mono and HIV/HCV coinfection.
Piekarska et al., Łódź, Poland. In Plos One, 2013
AIM: To analyze the expression of HMOX1 and miR-122 in liver biopsy samples obtained from HCV mono-and HIV/HCV co-infected patients in relation to selected clinical parameters, histological examination and IL-28B polymorphism as well as to determine whether HMOX1 expression is dependent on Bach-1.
Gene knockouts, in vivo site-directed mutagenesis and other modifications using the delitto perfetto system in Saccharomyces cerevisiae.
Storici et al., Atlanta, United States. In Methods Enzymol, 2012
Counterselectable markers, such as URA3, LYS2, LYS5, MET15, and TRP1 (Bach and LaCroute, 1972; Chattoo et al., 1979; Singh and Sherman, 1974; Toyn et al., 2000), are widely utilized in yeast and can be recycled for additional usage in the same yeast strain.
[Alitretinoin in chronic hand eczema: summary of clinical trials].
Richard, Marseille, France. In Ann Dermatol Venereol, 2010
In the second multicenter study (the Bach study), comparing the efficacy of a 12-week alitretinoin treatment (10 mg, 30 mg) to placebo for CHE, a "clear or almost clear" result was observed in 17% (placebo group), 28% (group alitretinoin 10 mg), and 48% (group alitretinoin 30 mg).
Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation.
Kobe et al., Brisbane, Australia. In Proc Natl Acad Sci U S A, 2007
The structural basis for recruitmment of tandem domains in Acot7 is demonstrated and its role in inflammation presented.
Alternative exon usage selectively determines both tissue distribution and subcellular localization of the acyl-CoA thioesterase 7 gene products.
Alexson et al., Huddinge, Sweden. In Cell Mol Life Sci, 2007
Acot7 gene is expressed as multiple isoforms in a tissue-specific manner; expression in tissues other than brain and testis is likely to play important roles in fatty acid metabolism.
Aberrant cytosolic acyl-CoA thioester hydrolase in hippocampus of patients with mesial temporal lobe epilepsy.
Lubec et al., Vienna, Austria. In Amino Acids, 2004
BACH was deranged in hippocampus of mesial temporal lobe epilepsy patients.
Human brain acyl-CoA hydrolase isoforms encoded by a single gene.
Suga et al., Hachiōji, Japan. In Biochem Biophys Res Commun, 2002
the human BACH gene can express long-chain acyl-CoA hydrolase activity in multiple intracellular compartments by generating BACH isoforms with differential localization signals to affect various cellular functions that involve acyl-CoAs
Characterization of mouse homolog of brain acyl-CoA hydrolase: molecular cloning and neuronal localization.
Yamada et al., Hachiōji, Japan. In Brain Res Mol Brain Res, 2002
mBACH cDNA encoded a 338-AA pp >95% identical to human and rat homologs. mBACH was distributed throughboth central and peripheral cell body and neurites. Another 50-kDa pp made from mBACH mRNA used different in-frame ATGs as initiation codon.
The HLA class II genes and products: the HLA-D region.
Bach, Minneapolis, United States. In Immunol Today, 1985
Here Fritz Bach summarizes this understanding, with emphasis on the T-lymphocyte defined LD system.
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