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Tumor necrosis factor, alpha-induced protein 2

B94, TNFAIP2, tumor necrosis factor alpha-induced protein 2
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, ACID, CAN, miR, V1a
Papers on B94
Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma.
Vandesompele et al., Gent, Belgium. In Oncotarget, Jan 2016
In total, 5 individual MSP assays (located in CCDC177, NXPH1, lnc-MRPL3-2, lnc-TREX1-1 and one on a region from chromosome 8 with no further annotation) predict event-free survival and 4 additional assays (located in SPRED3, TNFAIP2, NPM2 and CYYR1) also predict overall survival.
Enhancement of bifidobacteria survival by Williopsis saturnus var. saturnus in milk.
Liu et al., Singapore, Singapore. In Benef Microbes, Dec 2015
The B. lactis viable cell count for strains HN019 and BB-12 remained above 6.0 Log cfu/ml, while strain B94 had 5.7 Log cfu/ml after six weeks of incubation in the presence of the co-inoculated yeast.
SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells.
Vyas et al., Iowa City, United States. In Blood, Nov 2015
Consequently, proteins mediating adaptive immunity (IFNG, STAT1, TLR1) are deficient, whereas those mediating auto-inflammation (GM-CSF, TNFAIP2, IL-1β) are paradoxically increased in TH1 cells expressing SUMOylation-deficient WASp.
TNFAIP2 Inhibits Early TNFα-Induced NF-κB Signaling and Decreases Survival in Septic Shock Patients.
Walley et al., Stanford, United States. In J Innate Immun, Oct 2015
Using tag single-nucleotide polymorphisms in the genes common to all data sets, we identified a genetic variant of the TNFAIP2 gene, rs8126, associated with decreased 28-day survival and increased organ dysfunction in an adult cohort in the Vasopressin and Septic Shock Trial.
KLF5 promotes breast cancer proliferation, migration and invasion in part by upregulating the transcription of TNFAIP2.
Chen et al., Kunming, China. In Oncogene, Aug 2015
In this study, we demonstrate that TNFAIP2, a tumor necrosis factor-α (TNFα)-induced gene, is a direct KLF5 target gene.
Bifidobacterium lactis B94 plus inulin for Treatment of Helicobacter pylori infection in children: does it increase eradication rate and patient compliance?
Artan et al., In Acta Gastroenterol Belg, Jul 2015
The aim of this study is to investigate the effects of Bifidobacterium lactis B94 and inulin (synbiotic) treatment on eradication rate and patient compliance in subjects treated for symptomatic H. pylori infection.
MicroRNA-184 inhibits cell proliferation and invasion, and specifically targets TNFAIP2 in Glioma.
Zhou et al., Suzhou, China. In J Exp Clin Cancer Res, 2014
Studies have shown that miR-184 was down-regulated in glioma and TNFα-induced protein 2 (TNFAIP2) was closely related to tumorigenesis.
The role of Bifidobacterium lactis B94 plus inulin in the treatment of acute infectious diarrhea in children.
Artan et al., Antalya, Turkey. In Turk J Gastroenterol, 2014
We investigated the synbiotic effects of B. lactis B94 plus inulin on acute infectious diarrhea.
Differential Expression Profile of Chicken Embryo Fibroblast DF-1 Cells Infected with Cell-Adapted Infectious Bursal Disease Virus.
Leung et al., Hong Kong, Hong Kong. In Plos One, 2014
On the other hand, the caIBDV arrested the host's apoptotic process by inducing the expression of apoptosis inhibitors including NFKBIA/Z, TNFAIP2/3 and ITA at the first 12 hours of infection.
Supplementation of zinc on oocyte in vitro maturation improves preimplatation embryonic development in pigs.
Hyun et al., Ch'ŏngju, South Korea. In Theriogenology, 2014
TNFAIP2 and Bax were decreased in zinc-treated cumulus cells.
DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia.
Brim et al., Washington, D.C., United States. In Epigenetics, 2014
Fifty CpG sites located within CpG islands-in genes ATXN7L1 (2), BMP3 (7), EID3 (15), GAS7 (1), GPR75 (24), and TNFAIP2 (1)-were significantly hypermethylated in tumor vs. normal tissues (P<0.05).
A functional TNFAIP2 3'-UTR rs8126 genetic polymorphism contributes to risk of esophageal squamous cell carcinoma.
Zhou et al., Jinan, China. In Plos One, 2013
There is a TNFAIP2 3'-UTR rs8126 T>C genetic variant which has been proved to be associated with head and neck cancer susceptibility.
[Analysis of disease-pathway by identifying susceptible genes to primary biliary cirrhosis].
Makamura et al., Nagasaki, Japan. In Nihon Rinsho Meneki Gakkai Kaishi, 2011
Among 21 non-HLA susceptibility loci for PBC identified in GWASs of European descent, 10 loci (CD80, IKZF3, IL7R, NFKB1, STAT4, TNFAIP2, CXCR5, MAP3K7IP1, rs6974491, DENND1B) showed significant associations in the Japanese population.
A functional variant at the miR-184 binding site in TNFAIP2 and risk of squamous cell carcinoma of the head and neck.
Wei et al., Houston, United States. In Carcinogenesis, 2011
A functional variant at the miR-184 binding site in TNFAIP2 is associated with squamous cell carcinoma of the head and neck.
The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.
Yaspo et al., Berlin, Germany. In J Biol Chem, 2011
TNFAIP2 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.
A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma.
Hsueh et al., Taiwan. In Mod Pathol, 2011
TNFAIP2 is a cell migration-promoting protein and its expression predicts distant metastasis. Our data suggest that TNFAIP2 may serve as an independent prognostic indicator for nasopharyngeal carcinoma.
M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex.
Ohno et al., Japan. In Nat Cell Biol, 2009
Knockdown of TNFaip2 in Raw264.7 cells inhibited formation of tunneling nanotubes.
Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer.
Rao et al., Oklahoma City, United States. In Curr Mol Med, 2009
In light of existing knowledge on interconnected pathways of pro-inflammatory mediators (leukotrienes, chemokines (IL8, SDF-1 alpha, MIP-1 alpha, MCP-1,2 etc), and cytokines (IL3, IL6, IL12, IL-1 beta, GM-CSF, B94, TNF-alpha etc)), the anti-inflammatory properties of pro-resolving mediators in preventing chronic inflammation which leads to carcinogenesis needs further understanding.
Change in ribosomal DNA intergenic spacer-length composition in maize recurrent selection populations. 1. Analysis of BS13, BSSS, and BSCB1.
Rocheford, Urbana, United States. In Theor Appl Genet, 1994
Hybridization pattern D is present in the elite inbreds B89 and B94, which were derived from different cycles of the BSSS reciprocal recurrent selection program with BSCB1.
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